Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Adipose tissue browning"'
Autor:
Melanie Modder, Claudia P. Coomans, Dirk-Jan Saaltink, Mayke M. H. Tersteeg, Janna Hoogduin, Leonie Scholten, Amanda C. M. Pronk, Reshma A. Lalai, Anita Boelen, Andries Kalsbeek, Patrick C. N. Rensen, Erno Vreugdenhil, Sander Kooijman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Crosstalk between peripheral metabolic organs and the central nervous system is essential for body weight control. At the base of the hypothalamus, β-tanycytes surround the portal capillaries and function as gatekeepers to facilitate transf
Externí odkaz:
https://doaj.org/article/dfe49dbfc38e4ce386cd77ee4e307ebf
Autor:
Shieh-Yang Huang, Ming-Ting Chung, Ching-Wen Kung, Shu-Ying Chen, Yi-Wen Chen, Tong Pan, Pao-Yun Cheng, Hsin-Hsueh Shen, Yen-Mei Lee
Publikováno v:
Journal of Obesity & Metabolic Syndrome, Vol 33, Iss 2, Pp 177-188 (2024)
Background : AMP-activated protein kinase (AMPK) is a key enzyme for cellular energy homeostasis and improves metabolic disorders. Brown and beige adipose tissues exert thermogenesis capacities to dissipate energy in the form of heat. Here, we invest
Externí odkaz:
https://doaj.org/article/d4b5a6e3db3d413f96a5229e58304255
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 951-68 (2024)
This study investigated how Metformin (Met) combined with L-carnitine (L-car) modulates brown adipose tissue (BAT) to affect obesity. High-fat-induced obese rats received daily oral gavage with Met and/or L-car, followed by serum biochemical analysis
Externí odkaz:
https://doaj.org/article/72c1559544ff472383e452ce54a21ca9
Autor:
Qinhao Wang, Yuanyuan Su, Ruiqi Sun, Xin Xiong, Kai Guo, Mengying Wei, Guodong Yang, Yi Ru, Zhengxiang Zhang, Jing Li, Jing Zhang, Qing Qiao, Xia Li
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Background The enrichment of peri-cancerous adipose tissue is a distinctive feature of colorectal cancer (CRC), accelerating disease progression and worsening prognosis. The communication between tumor cells and adjacent adipocytes plays a c
Externí odkaz:
https://doaj.org/article/c6c9723a741d47ae815822ef335e3410
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10514 (2024)
Sirtuin 5 (SIRT5) plays an important role in the maintenance of lipid metabolism and in white adipose tissue browning. In this study, we established a mouse model for diet-induced obesity and the browning of white fat; combined with gene expression i
Externí odkaz:
https://doaj.org/article/54bf600fc4df4dd395b23f5c9fd90aea
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3330 (2024)
Background/Objectives: The global prevalence of obesity and its associated health complications represent significant public health concerns. Plant polysaccharides have been demonstrated to possess a range of beneficial pharmacological effects. This
Externí odkaz:
https://doaj.org/article/3e37f5dd60d747a5bd3c5ed3a7156fbc
Publikováno v:
Cells, Vol 13, Iss 17, p 1485 (2024)
Lung cancer and cachexia are the leading causes of cancer-related deaths worldwide. Cachexia is manifested by weight loss and white adipose tissue (WAT) atrophy. Limited nutritional supplements are conducive to lung cancer patients, whereas the under
Externí odkaz:
https://doaj.org/article/20128341886c4f6884165b19621738af
Autor:
Xiaojie Liu, Xi Jiang, Jing Hu, Mingxing Ding, Sang Ki Lee, Mallikarjuna Korivi, Yongdong Qian, Ting Li, Lifeng Wang, Wei Li
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundPerivascular adipose tissue (PVAT) dysfunction impairs vascular homeostasis. Impaired inflammation and bone morphogenetic protein-4 (BMP4) signaling are involved in thoracic PVAT dysfunction by regulating adipokine secretion and adipocyte p
Externí odkaz:
https://doaj.org/article/26bc25955db04dd2aca035113df5bdc9
Autor:
Yuhan Meng, Weili Li, Chenxing Hu, Si Chen, Haiyang Li, Feifei Bai, Lujuan Zheng, Ye Yuan, Yuying Fan, Yifa Zhou
Publikováno v:
Food Science and Human Wellness, Vol 12, Iss 6, Pp 2061-2072 (2023)
Obesity-induced type 2 diabetes is mainly due to excessive free fatty acids leading to insulin resistance. Increasing thermogenesis is regarded as an effective strategy for hypolipidemia and hypoglycemia. Ginsenoside is a natural active component in
Externí odkaz:
https://doaj.org/article/e97002b356ec407a93f6642afaa74f82
Autor:
Magdalena Kotańska, Monika Zadrożna, Monika Kubacka, Kamil Mika, Katarzyna Szczepańska, Barbara Nowak, Alessio Alesci, Anthea Miller, Eugenia Rita Lauriano, Katarzyna Kieć-Kononowicz
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 858 (2024)
Background: Numerous studies highlight the critical role that neural histamine plays in feeding behavior, which is controlled by central histamine H3 and H1 receptors. This is the fundamental motivation for the increased interest in creating histamin
Externí odkaz:
https://doaj.org/article/a89f1fff18ba46f69f8f2291d9821f40