Výsledky vyhledávání - "Adipocytes

Parathyroid hormone receptor stimulation induces human adipocyte lipolysis and browning

Autor: Niels Jessen, Bjørn Richelsen, Steen B. Pedersen, Peter Breining, Jacob B. Hansen, Mads Kjolby

Publikováno v: Breining, P, Pedersen, S B, Kjolby, M, Hansen, J B, Jessen, N & Richelsen, B 2021, ' Parathyroid hormone receptor stimulation induces human adipocyte lipolysis and browning ', European Journal of Endocrinology, vol. 184, no. 5, pp. 687-697 . https://doi.org/10.1530/EJE-20-0713

Objective Activation of brown adipose tissue is a promising strategy to treat and prevent obesity and obesity-related disorders. Activation of uncoupling protein 1 (UCP1) leads to uncoupled respiration and dissipation of stored energy as heat. Induct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9393d6212f2abdcb21a7db48ea58f29
https://doi.org/10.1530/eje-20-0713

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Gene Expression Pattern in Response to Cholecalciferol Supplementation Highlights Cubilin as a Major Protein of 25(OH)D Uptake in Adipocytes and Male Mice White Adipose Tissue

Autor: Catherine Defoort, Esma Karkeni, Lauriane Bonnet, Jean-François Landrier, Jean-Charles Martin, Charlène Couturier, Julie Dalifard, Franck Tourniaire, Ljubica Svilar, Julien Astier

Publikováno v: Endocrinology
Endocrinology, 2018, 159 (2), pp.957-966. ⟨10.1210/en.2017-00650⟩
Endocrinology, Endocrine Society, 2018, 159 (2), pp.957-966. ⟨10.1210/en.2017-00650⟩

International audience; It is well established that the active form of vitamin D (i.e., 1,25-dihydroxyvitamin D [1,25(OH)2D]) regulates the expression of genes involved in its own metabolism and transport in the kidney and possibly in the liver. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b72d54a4233ab33c63bda0d37451eb
https://amu.hal.science/hal-01998528

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ENDOCRINE DISRUPTORS AND OBESITY

Autor: Ćurić, Melany, Klobučar Majanović, Sanja, Detel, Dijana, Ružić, Alen, Štimac, Davor

Publikováno v: Liječnički vjesnik
Volume 139
Issue 7-8

Porast prevalencije debljine postaje ozbiljan globalni javnozdravstveni problem. Osim nezdrave prehrane i smanjene tjelesne aktivnosti, razni kemijski spojevi koji se nalaze svuda oko nas mogu biti jedan od etioloških čimbenika razvoja debljine i n

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https://urn.nsk.hr/urn:nbn:hr:184:762954

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The effect of pH-neutral peritoneal dialysis fluids on adipokine secretion from cultured adipocytes

Autor: Daniel Teta, Marc Maillard, Andrée Tedjani, Michel Burnier, Jutta Passlick-Deetjen

Publikováno v: Nephrology, Dialysis, Transplantation, vol. 22, no. 3, pp. 862-9

BACKGROUND: Adipokines are a group of fat-secreted hormones and cytokines, including leptin and adiponectin, with important functions in humans. Peritoneal dialysis (PD) is associated with markedly raised plasma adipokines, suggesting increased produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519f11c40391e66fae4a4443fdbdc278
http://doc.rero.ch/record/302208/files/gfl698.pdf

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ENDOKRINI DISRUPTORI I DEBLJINA

Autor: Melany Ćurić, Sanja Klobučar Majanović, Dijana Detel, Alen Ružić, Davor Štimac

Publikováno v: Liječnički vjesnik
Volume 139
Issue 7-8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______951::128a8f2c06764c5d08eaa4daf2ebdff2
https://hrcak.srce.hr/file/279555

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Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

Autor: Nehad M. Alajez, Musaed Alfayez, Moustapha Kassem, Rimi Hamam, Dalia Ali, Abdullah Aldahmash

Publikováno v: Ali, D, Hamam, R, Alfayez, M, Kassem, M, Aldahmash, A & Alajez, N M 2016, ' Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells ', Stem Cells Translational Medicine, vol. 5, no. 8, pp. 1036-1047 . https://doi.org/10.5966/sctm.2015-0331
Stem Cells Translational Medicine, Vol 5, Iss 8, Pp 1036-1047 (2016)

The epigenetic mechanisms promoting lineage-specific commitment of human skeletal (mesenchymal or stromal) stem cells (hMSCs) into adipocytes or osteoblasts are still not fully understood. Herein, we performed an epigenetic library functional screen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a0470d79cc6be8aed62e38f8746b4a
https://europepmc.org/articles/PMC4954455/

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Activation of Peroxisome Proliferator–Activated Receptor-β/-δ (PPAR-β/-δ) Ameliorates Insulin Signaling and Reduces SOCS3 Levels by Inhibiting STAT3 in Interleukin-6–Stimulated Adipocytes

Autor: Walter Wahli, Liliane Michalik, Lucía Serrano-Marco, Xavier Palomer, Manuel Vázquez-Carrera, Ilhem El Kochairi, Ricardo Rodríguez-Calvo

Publikováno v: Diabetes
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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Diabetes, vol. 60, no. 7, pp. 1990-1999

OBJECTIVE It has been suggested that interleukin (IL)-6 is one of the mediators linking obesity-derived chronic inflammation with insulin resistance through activation of STAT3, with subsequent upregulation of suppressor of cytokine signaling 3 (SOCS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd092aca90dd0fa90905d0243bd5a3e
https://doi.org/10.2337/db10-0704

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Glucose-containing peritoneal dialysis fluids regulate leptin secretion from 3T3-L1 adipocytes

Autor: Andrée Tedjani, Alan Bevington, Jeremy M. C. Brown, Kevin P.G. Harris, Michel Burnier, Daniel Teta

Publikováno v: Nephrology, Dialysis, Transplantation, vol. 20, no. 7, pp. 1329-35

BACKGROUND: A marked elevation of serum leptin is observed soon after the start of peritoneal dialysis (PD), suggesting that leptin production may be stimulated by this treatment. Glucose metabolism is the major factor regulating leptin. The current

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cbf1507d7359f2c2af0492c8951601
https://doi.org/10.1093/ndt/gfh812

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Mitochondrial DNA Levels in Fat and Blood Cells from Patients with Lipodystrophy or Peripheral Neuropathy and the Effect of 90 Days of High-Dose Coenzyme Q Treatment: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

Autor: Eva Rabing Christensen, Søren Jensen-Fangel, Lars Østergaard, Marc Stegger, Alex Lund Laursen

Publikováno v: Rabing Christensen, E, Stegger, M, Jensen-Fangel, S, Laursen, A L & Ostergaard, L 2004, ' Mitochondrial DNA levels in fat and blood cells from patients with lipodystrophy or peripheral neuropathy and the effect of 90 days of high-dose coenzyme Q treatment : a randomized, double-blind, placebo-controlled pilot study ', Clinical Infectious Diseases, vol. 39, no. 9, pp. 1371-1379 . https://doi.org/10.1086/424881

BACKGROUND: Mitochondrial toxicity can be induced by reverse-transcriptase inhibitors, and an association between levels of mitochondrial DNA (mtDNA) per cell and lipodystrophy, peripheral neuropathy, and HIV infection per se has been suggested. Stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1743df2b63e76139a0f0559f7c3fd03
https://doi.org/10.1086/424881

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Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor

Autor: Graeme Milligan, Sunil K. Pandey, Brian D. Hudson, Amanda E. Mackenzie, Irina G. Tikhonova, Elisabeth Christiansen, Hannah Murdoch, Maria E Due-Hansen, Trond Ulven, Anna Mette Hansen, Richard J. Ward, Rudi Marquez

Publikováno v: The Journal of Biological Chemistry
Hudson, B D, Due-Hansen, M E, Christiansen, E, Hansen, A M, Mackenzie, A E, Murdoch, H, Pandey, S K, Ward, R J, Marquez, R, Tikhonova, I G, Ulven, T & Milligan, G 2013, ' Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor ', Journal of Biological Chemistry, vol. 288, no. 24, pp. 17296-17312 . https://doi.org/10.1074/jbc.M113.455337
Hudson, B D, Due-Hansen, M E, Christiansen, E, Hansen, A, Mackenzie, A E, Murdoch, H, Pandey, S K, Ward, R J, Marquez, R, Tikhonova, I G, Ulven, T & Milligan, G 2013, ' Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor ', Journal of Biological Chemistry, vol. 288, pp. 17296-17312 . https://doi.org/10.1074/jbc.M113.455337

Background: Understanding the function of FFA2 has been slowed by a lack of selective orthosteric ligands. Results: Residues within FFA2 that dictate the recognition and function of potent and selective orthosteric agonists are described. Conclusion:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc95593b410c8497ec6ceed8e3f6d972
https://pubmed.ncbi.nlm.nih.gov/23589301

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