Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Adina M. Bailey"'
Autor:
Karen E. Knudsen, Nupam P. Mahajan, Housheng Hansen He, Martin Sjöström, Kathleen E. Houlahan, Jianhua Luo, S. Laura Chang, Meng Zhang, Kim N. Chi, Paul C. Boutros, Joseph F. Costello, Adam Foye, Denise Playdle, Lawrence Fong, M. Yvonne Kim, Serafim Batzoglou, Martin E. Gleave, Rahul Aggarwal, Li Zhang, Eric D. Chow, Scott A. Tomlins, Felix Y. Feng, Jiaoti Huang, Franklin W. Huang, Hui Li, Haolong Li, George Thomas, Junjie Tony Hua, Irfan A. Asangani, Marc D. Perry, Ha X. Dang, Todd M. Morgan, Robert E. Reiter, Alexander W. Wyatt, Shahneen Sandhu, Amina Zoubeidi, Christopher G. Maher, Daniel E. Spratt, Tanushree R. Shenoy, Luke A. Gilbert, Arul M. Chinnaiyan, Joshi J. Alumkal, Scott M. Dehm, Phillip G. Febbo, Primo N. Lara, Tomasz M. Beer, Adina M. Bailey, Rajdeep Das, Owen N. Witte, Alan Ashworth, Lisa N. Chesner, Joshua M. Lang, Mohammed Alshalalfa, Eric J. Small, Rohit Bose, Wilbert Zwart, David A. Quigley, Christopher P. Evans, Arnold Liao, Shuang G. Zhao, Yu Jia Shiah, Kyle Kai-How Farh, Hani Goodarzi, Travis J. Barnard, William S. Chen, Rendong Yang, Jonathan Chou, Ruhollah Moussavi-Baygi, Matthew Rettig
Publikováno v:
Nature genetics
Nature genetics, vol 52, iss 8
Nature genetics, vol 52, iss 8
Although DNA methylation is a key regulator of gene expression, the comprehensive methylation landscape of metastatic cancer has never been defined. Through whole-genome bisulfite sequencing paired with deep whole-genome and transcriptome sequencing
Autor:
Eric J. Small, Robert E. Reiter, Alana S. Weinstein, Verena Friedl, Felix Y. Feng, Kim N. Chi, Martin E. Gleave, George Thomas, Rahul Aggarwal, Josh Stuart, Joshi J. Alumkal, Jiaoti Huang, Adam Foye, Lawrence D. True, Tomasz M. Beer, Primo N. Lara, Matthew Rettig, Christopher P. Evans, Adina M. Bailey
Publikováno v:
Journal of Clinical Oncology. 38:158-158
158 Background: A subset of mCRPC patients (pts) that develop resistance to next-gen androgen signaling inhibitors are subsequently found to harbor t-SCNC. We have undertaken a longitudinal prospective biopsy (bx) study to clinically and molecularly
Autor:
Eric J. Small, William S. Chen, Matthew Rettig, Patricia Li, Verena Friedl, Felix Y. Feng, Josh Stuart, Tomasz M. Beer, Martin E. Gleave, Joshi J. Alumkal, Alana S. Weinstein, Daniel Kwon, Adina M. Bailey, Li Zhang, Jiaoti Huang, Rahul Aggarwal, Adam Foye, Primo N. Lara, David A. Quigley, Austin Lui
Publikováno v:
Journal of Clinical Oncology. 38:145-145
145 Background: The net oncogenic effect of the G protein-coupled receptor β2 adrenergic receptor ADRB2, which may induce neuroendocrine differentiation via cyclic AMP and protein kinase A and whose expression is epigenetically regulated by EZH2, is
Autor:
Eric J. Small, Lawrence Fong, Karen E. Knudsen, Brad Sickler, Robert E. Reiter, Charles J. Ryan, Theodore C. Goldstein, Tomasz M. Beer, Martin E. Gleave, Rahul Aggarwal, Julian S. Gehring, Rajdeep Das, John Shon, Scott M. Dehm, Alan Ashworth, David A. Quigley, Ha X. Dang, Terence W. Friedlander, R. Keira Cheetham, Denise Playdle, Paul Lloyd, Serafim Batzoglou, Jack F. Youngren, Jin Zhang, Nathan A. Lack, Adam Foye, Felix Y. Feng, Jörg Hakenberg, Adina M. Bailey, Owen N. Witte, Abhijit Parolia, Scott A. Tomlins, Travis J. Barnard, Donavan T. Cheng, Jiaoti Huang, Li Zhang, P. G. Febbo, Alexander W. Wyatt, Kim N. Chi, Matthew Rettig, Vishal Kothari, Daniel E. Spratt, Housheng Hansen He, Haolong Li, George Thomas, Arnold Liao, Shuang G. Zhao, Hui Li, Joshua M. Stuart, Won Kim, Primo N. Lara, Christopher G. Maher, Jonathan Chou, Joshi J. Alumkal, Amina Zoubeidi, Marc D. Perry, Ruhollah Moussavi-Baygi, Luke A. Gilbert, Arul M. Chinnaiyan, Christopher P. Evans, Hani Goodarzi, Marcin Cieslik, Kyle Kai-How Farh
Publikováno v:
Cell, vol 174, iss 3
Quigley, DA; Dang, HX; Zhao, SG; Lloyd, P; Aggarwal, R; Alumkal, JJ; et al.(2018). Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell, 174(3), 758-769.e9. doi: 10.1016/j.cell.2018.06.039. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/796124qb
Quigley, DA; Dang, HX; Zhao, SG; Lloyd, P; Aggarwal, R; Alumkal, JJ; et al.(2018). Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell, 174(3), 758-769.e9. doi: 10.1016/j.cell.2018.06.039. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/796124qb
© 2018 Elsevier Inc. While mutations affecting protein-coding regions have been examined across many cancers, structural variants at the genome-wide level are still poorly defined. Through integrative deep whole-genome and -transcriptome analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1928a409b1341bcafb393804416865b5
https://escholarship.org/uc/item/796124qb
https://escholarship.org/uc/item/796124qb
Autor:
Alemu Belachew, Leslie Edwards, Roger D. Canales, Peter P. Repetti, Luc Adam, Andreah D. Wallace, Hans E. Holtan, Colleen M. Marion, Adina M. Bailey, Jeffrey K. Stone, Oliver J. Ratcliffe, Yu Shen, Shiv B. Tiwari, Melinda Young, Jules Ade, Siu Fong Ma
Publikováno v:
The Plant Journal. 70:855-865
Summary In plants, the ERF/EREBP family of transcriptional regulators plays a key role in adaptation to various biotic and abiotic stresses. These proteins contain a conserved AP2 DNA-binding domain and several uncharacterized motifs. Here, we descri
Autor:
Sima Misra, Martha Evans-Holm, Susan E. Celniker, Gina Dailey, Jonathan L. Tupy, Christian W. Siebel, Gerald M. Rubin, Adina M. Bailey
Publikováno v:
Proceedings of the National Academy of Sciences. 102:5495-5500
Analysis of EST and cDNA collections from a number of metazoan species has identified genes encoding long polyadenylated transcripts that do not contain ORFs of lengths typical for protein-encoding mRNAs. Noncoding functions of such polyadenylated tr
Autor:
Mark Yandell, Sima Misra, Adina M. Bailey, Martha Evans-Holm, Gerald M. Rubin, ShengQiang Shu, Susan E. Celniker, Colin Wiel
Publikováno v:
Proceedings of the National Academy of Sciences. 102:1566-1571
Five years after the completion of the sequence of the Drosophila melanogaster genome, the number of protein-coding genes it contains remains a matter of debate; the number of computational gene predictions greatly exceeds the number of validated gen
Autor:
Yong Q. Zhang, Robert Renden, Sean D. Speese, Mark A. Smith, Adina M. Bailey, Gerald M. Rubin, Heinrich J.G. Matthies, Kendal Broadie
Publikováno v:
Cell. 107:591-603
Fragile X mental retardation gene (FMR1) encodes an RNA binding protein that acts as a negative translational regulator. We have developed a Drosophila fragile X syndrome model using loss-of-function mutants and overexpression of the FMR1 homolog (df
Publikováno v:
Mechanisms of Development. 40:25-36
The pro-neural achaete-scute complex (ASC) of Drosophila encodes four homologous proteins, each containing a basic helix-loop-helix (bHLH) domain, characteristic of a large family of transcription factors. We have isolated XASH1 , a Xenopus homolog o
Autor:
Kornélia Szabó, Marco Milán, Todd R. Laverty, Wilhelm Ansorge, Jay Rehm, Gerald M. Rubin, Katrin Weigmann, Pernille Rørth, Stephen M. Cohen, Vladimir Benes, Adina M. Bailey
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
A modular misexpression system was used to carry out systematic gain-of-function genetic screens in Drosophila. The system is based on inducible expression of genes tagged by insertion of a P-element vector carrying a GAL4-regulated promoter oriented