Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Adina F Turcu"'
Autor:
Mônica Gadelha, Peter J. Snyder, Przemysław Witek, Marie Bex, Zhanna Belaya, Adina F. Turcu, Richard A. Feelders, Anthony P. Heaney, Michaela Paul, Alberto M. Pedroncelli, Richard J. Auchus
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectiveTo evaluate the long-term efficacy and safety of osilodrostat in patients with Cushing’s disease.MethodsThe multicenter, 48-week, Phase III LINC 4 clinical trial had an optional extension period that was initially intended to continue to w
Externí odkaz:
https://doaj.org/article/372be9dc61a0418b932676d46aae10b2
Autor:
Adina F. Turcu, Winnie Nhan, Seda Grigoryan, Lei Zhang, Caitlin Urban, Haiping Liu, Lynn Holevinski, Lili Zhao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 14 (2022)
Background Primary aldosteronism (PA) is a common but under‐recognized cause of secondary hypertension. Data directly comparing screening rates across single and overlapping indications are lacking. Methods and Results We conducted a retrospective
Externí odkaz:
https://doaj.org/article/48efe3c07ce14097bd05ce06ab435c66
Autor:
Adina F. Turcu, Ashwini Mallappa, Aikaterini A. Nella, Xuan Chen, Lili Zhao, Aya T. Nanba, James Brian Byrd, Richard J. Auchus, Deborah P. Merke
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundOptimal management of androgen excess in 21-hydroxylase deficiency (21OHD) remains challenging. 11-oxygenated-C19 steroids (11-oxyandrogens) have emerged as promising biomarkers of disease control, but data regarding their response to treat
Externí odkaz:
https://doaj.org/article/e678b04d9d664e889f9b3bec448def53
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundSomatic gene mutations that facilitate inappropriate intracellular calcium entrance have been identified in most aldosterone-producing adenomas (APAs). Studies suggest that angiotensin II and adrenocorticotropic hormone (ACTH) augment aldos
Externí odkaz:
https://doaj.org/article/ac4d57a521834026b6421b68ad4db9eb
Autor:
Yuta Tezuka, Adina F. Turcu
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ObjectiveTo investigate how often target renin is pursued and achieved in patients with primary aldosteronism (PA) and other low renin hypertension (LRH) treated with mineralocorticoid receptor antagonists (MRAs), as reversal of renin suppression was
Externí odkaz:
https://doaj.org/article/92bf4667b98e48529eb0bc1eea072ec2
Publikováno v:
Nature Reviews Endocrinology. 18:665-682
Primary aldosteronism is a common cause of hypertension and is a risk factor for cardiovascular and renal morbidity and mortality, via mechanisms mediated by both hypertension and direct insults to target organs. Despite its high prevalence and assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c816f3e47f97a86701c85c565773b10
https://doi.org/10.1038/s41574-022-00730-2
https://doi.org/10.1038/s41574-022-00730-2
Autor:
Suranut Charoensri, Adina F. Turcu
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes.
Primary aldosteronism (PA) is characterized by dysregulated, renin-independent aldosterone excess. Long perceived as rare, PA has emerged as one of the most common causes of secondary hypertension. Failure to recognize and treat PA results in cardiov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7111b32da49c5519e10780fe9b0a95c5
https://doi.org/10.1055/a-2066-2696
https://doi.org/10.1055/a-2066-2696
Publikováno v:
Current Hypertension Reports. 24:123-132
Primary aldosteronism (PA) affects millions of individuals worldwide. When unrecognized, PA leads to cardiovascular and renal complications via mechanisms independent from those mediated by hypertension. In this review, we emphasize the importance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15c21539f631fa794686be58d4d80a2
https://doi.org/10.1007/s11906-022-01176-7
https://doi.org/10.1007/s11906-022-01176-7
Autor:
Morgan N Cash, James M. Luther, Adina F. Turcu, Chia Jen Liu, Thomas J. Giordano, Jessie Hoxie, Kazutaka Nanba, Lan L. Gellert, Aaron M. Udager, William E. Rainey, Tobias Else, Juilee Rege
Publikováno v:
J Clin Endocrinol Metab
ContextSomatic gene mutations have been identified in only about half of cortisol-producing adenomas (CPAs). Affected genes include PRKACA, GNAS, PRKAR1A, and CTNNB1.ObjectiveThis work aims to expand our understanding of the prevalence of somatic mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0c6b03a15f5d9cc2f57493472b00a3
https://doi.org/10.1210/clinem/dgab682
https://doi.org/10.1210/clinem/dgab682
Autor:
Jordana B. Cohen, Irina Bancos, Jenifer M. Brown, Harini Sarathy, Adina F. Turcu, Debbie L. Cohen
Publikováno v:
Annual review of medicine.
Primary aldosteronism (PA) is the most common cause of secondary hypertension but is frequently underrecognized and undertreated. Patients with PA are at a markedly increased risk for target organ damage to the heart and kidneys. While patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1316e96b67bba104fbb8965737f4f69c
https://pubmed.ncbi.nlm.nih.gov/36375469
https://pubmed.ncbi.nlm.nih.gov/36375469