Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Adina Borbély"'
Autor:
Balázs Vári, Levente Dókus, Adina Borbély, Anikó Gaál, Diána Vári-Mező, Ivan Ranđelović, Anna Sólyom-Tisza, Zoltán Varga, Norbert Szoboszlai, Gábor Mező, József Tóvári
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractChemotherapy is still a leading therapeutic approach in various tumor types that is often accompanied by a poor prognosis because of metastases. PEGylated liposomes with CREKA targeting moiety are well-known therapeutic agents, especially in
Externí odkaz:
https://doaj.org/article/20072f91186a426695d8bc4c72c657cf
Autor:
Dávid Virág, Gitta Schlosser, Adina Borbély, Gabriella Gellén, Dávid Papp, Zoltán Kaleta, Borbála Dalmadi-Kiss, István Antal, Krisztina Ludányi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4656 (2024)
Mass spectrometry has become the most prominent yet evolving technology in quantitative proteomics. Today, a number of label-free and label-based approaches are available for the relative and absolute quantification of proteins and peptides. However,
Externí odkaz:
https://doaj.org/article/5648af4aa119427487ecb9979c4dbc1a
Autor:
Marco Zambra, Ivan Ranđelović, Francesco Talarico, Adina Borbély, Laura Svajda, József Tóvári, Gábor Mező, Lizeth Bodero, Sveva Colombo, Federico Arrigoni, Elettra Fasola, Silvia Gazzola, Umberto Piarulli
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Antibody-Drug Conjugates (ADCs) and Small Molecule-Drug Conjugates (SMDCs) represent successful examples of targeted drug-delivery technologies for overcoming unwanted side effects of conventional chemotherapy in cancer treatment. In both strategies,
Externí odkaz:
https://doaj.org/article/8398d4cb126548328281d797762b4133
Autor:
Dóra Nagy-Fazekas, Pál Stráner, Péter Ecsédi, Nóra Taricska, Adina Borbély, László Nyitray, András Perczel
Publikováno v:
Bioengineering, Vol 10, Iss 3, p 389 (2023)
Antibodies are key proteins of the immune system, and they are widely used for both research and theragnostic applications. Among them, camelid immunoglobulins (IgG) differ from the canonical human IgG molecules, as their light chains are completely
Externí odkaz:
https://doaj.org/article/532fcbcce04c4c5eaab7d71a9c0ff521
Autor:
Jacopo Gomena, Balázs Vári, Rita Oláh-Szabó, Beáta Biri-Kovács, Szilvia Bősze, Adina Borbély, Ádám Soós, Ivan Ranđelović, József Tóvári, Gábor Mező
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3400 (2023)
Targeted tumour therapy has proved to be an efficient alternative to overcome the limitations of conventional chemotherapy. Among several receptors upregulated in cancer cells, the gastrin-releasing peptide receptor (GRP-R) has recently emerged as a
Externí odkaz:
https://doaj.org/article/9ca8224a45fb4ab5be03320a2344d728
Autor:
Adina Borbély, Dr. Eduard Figueras, Ana Martins, Dr. Lizeth Bodero, Dr. André Raposo Moreira Dias, Dr. Paula López Rivas, Dr. Arianna Pina, Dr. Daniela Arosio, Dr. Paola Gallinari, Dr. Marcel Frese, Dr. Christian Steinkühler, Prof. Dr. Cesare Gennari, Prof. Dr. Umberto Piarulli, Prof. Dr. Norbert Sewald
Publikováno v:
ChemistryOpen, Vol 8, Iss 6, Pp 737-742 (2019)
Abstract RGD‐cryptophycin and isoDGR‐cryptophycin conjugates were synthetized by combining peptidomimetic integrin ligands and cryptophycin, a highly potent tubulin‐binding antimitotic agent across lysosomally cleavable Val‐Ala or uncleavable
Externí odkaz:
https://doaj.org/article/d3a79dc0bab74335b6cc1b9cbbeb2934
Autor:
Tamás Czuczi, József Murányi, Péter Bárány, István Móra, Adina Borbély, Miklós Csala, Antal Csámpai
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 468 (2022)
Imipridones, including ONC201, ONC206 and ONC212 (which are emblematic members of this class of compounds developed by Oncoceutics) constitute a novel class of anticancer agents, with promising results in clinical trials. With the aim of increasing t
Externí odkaz:
https://doaj.org/article/754deb64b98c4fbcb5d62e61c85c104d
Autor:
Samuele Cazzamalli, Eduard Figueras, Lilla Pethő, Adina Borbély, Christian Steinkühler, Dario Neri, Norbert Sewald
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 14726-14731 (2018)
Externí odkaz:
https://doaj.org/article/1dbd508179914e53a63876afc1a200a8
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 1281-1286 (2018)
Cryptophycins are naturally occurring cytotoxins with great potential for chemotherapy. Since targeted therapy provides new perspectives for treatment of cancer, new potent analogues of cytotoxic agents containing functional groups for conjugation to
Externí odkaz:
https://doaj.org/article/59ad3118b19f41c584589f601ebe3945
Autor:
Dávid Virág, Tibor Kremmer, Kende Lőrincz, Norbert Kiss, Antal Jobbágy, Szabolcs Bozsányi, Lili Gulyás, Norbert Wikonkál, Gitta Schlosser, Adina Borbély, Zsófia Huba, Borbála Dalmadi Kiss, István Antal, Krisztina Ludányi
Publikováno v:
Molecules, Vol 26, Iss 19, p 6003 (2021)
A high-resolution HILIC-MS/MS method was developed to analyze anthranilic acid derivatives of N-glycans released from human serum alpha-1-acid glycoprotein (AGP). The method was applied to samples obtained from 18 patients suffering from high-risk ma
Externí odkaz:
https://doaj.org/article/17a20330ee6c4b21bfbab4d3a0fe5f3c