Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Adina, Heinberg"'
Autor:
Sandra Völs, Naomi Kaisar-Iluz, Merav E. Shaul, Arik Ryvkin, Haim Ashkenazy, Avishag Yehuda, Ronza Atamneh, Adina Heinberg, Meital Ben-David-Naim, Menucha Nadav, Shira Hirsch, Vera Mitesser, Seth J. Salpeter, Ron Dzikowski, Zvi Hayouka, Jonathan M. Gershoni, Zvi G. Fridlender, Zvi Granot
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neutrophils play critical roles in a broad spectrum of clinical conditions. Accordingly, manipulation of neutrophil function may provide a powerful immunotherapeutic approach. However, due to neutrophils characteristic short half-life and their large
Externí odkaz:
https://doaj.org/article/215320c31c0b4edbb720d0fc23fc1890
Autor:
Manish Goyal, Adina Heinberg, Vera Mitesser, Sofiya Kandelis-Shalev, Brajesh Kumar Singh, Ron Dzikowski
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Plasmodium falciparum
Externí odkaz:
https://doaj.org/article/26440e9cd0994e80a988e827e40f5227
Autor:
Odelia Tepper, Itamar Peled, Yair Fastman, Adina Heinberg, Vera Mitesser, Ron Dzikowski, Eylon Yavin
Publikováno v:
ACS Sensors. 7:50-59
Autor:
Adina, Heinberg, Inbar, Amit-Avraham, Vera, Mitesser, Karina, Simantov, Manish, Goyal, Yuval, Nevo, Sofia, Kandelis-Shalev, Emilie, Thompson, Ron, Dzikowski
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(33)
The virulence of
Autor:
Adina Heinberg, Inbar Amit-Avraham, Vera Mitesser, Karina Simantov, Manish Goyal, Yuval Nevo, Sofia Kandelis-Shalev, Emilie Thompson, Ron Dzikowski
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The virulence of Plasmodium falciparum , which causes the deadliest form of human malaria, is attributed to its ability to evade the human immune response. These parasites “choose” to express a single variant from a repertoire of surface antigens
Autor:
Adina, Heinberg, Zvi, Granot
Publikováno v:
Nature Cancer. 3:136-137
Autor:
Brajesh Kumar Singh, Adina Heinberg, Ron Dzikowski, Manish Goyal, Sofiya Kandelis-Shalev, Vera Mitesser
Publikováno v:
mSphere
mSphere, Vol 6, Iss 1 (2021)
mSphere, Vol 6, Iss 1 (2021)
Plasmodium falciparum is the deadliest human parasite that causes malaria when it reaches the bloodstream and begins proliferating inside red blood cells, where the parasites are particularly prone to DNA damage. The molecular mechanisms that allow t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063263055099029671402f5364a6d145
https://doi.org/10.1101/2020.11.06.372391
https://doi.org/10.1101/2020.11.06.372391
The molecular basis of antifolate resistance inPlasmodium falciparum: looking beyond point mutations
Autor:
Laura A. Kirkman, Adina Heinberg
Publikováno v:
Annals of the New York Academy of Sciences. 1342:10-18
Drugs that target the folate synthesis pathway have a long history of effectiveness against a variety of pathogens. As antimalarials, the antifolates were safe and well tolerated, but resistance emerged quickly and has persisted even with decreased d
Autor:
Nattida Suwanakitti, Sastra Chaotheing, Adina Heinberg, Prapon Wilairat, Eric H. Ekland, Yongyuth Yuthavong, Laura A. Kirkman, Piyaporn Jirawatcharadech, Thanat Chookajorn, Kirk W. Deitsch, Pornpimol Chobson, Krittikorn Kümpornsin, David A. Fidock, Charin Modchang, Sumalee Kamchonwongpaisan
Publikováno v:
Molecular Biology and Evolution. 31:1649-1660
Biological robustness allows mutations to accumulate while maintaining functional phenotypes. Despite its crucial role in evolutionary processes, the mechanistic details of how robustness originates remain elusive. Using an evolutionary trajectory an
Autor:
Adina Heinberg, Laura A. Kirkman, Chaya D. Stern, Edwin Siu, Kirk W. Deitsch, Michael T. Ferdig, Elizabeth A. Lawrence
Publikováno v:
Molecular Microbiology. 88:702-712
Summary Resistance to antimalarials targeting the folate pathway is widespread. GTP-cyclohydrolase (gch1), the first enzyme in this pathway, exhibits extensive copy number variation (CN) in parasite isolates from areas with a history of longstanding