Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Adin Kugelmass"'
Autor:
Xun Ma, Sandy W. Wong, Ping Zhou, Chakra P. Chaulagain, Parul Doshi, Andreas K. Klein, Kellie Sprague, Adin Kugelmass, Denis Toskic, Melissa Warner, Kenneth B. Miller, Lisa Lee, Cindy Varga, Raymond L. Comenzo
Publikováno v:
Experimental Hematology & Oncology, Vol 7, Iss 1, Pp 1-10 (2018)
Abstract Background The monoclonal antibody daratumumab, approved for treating myeloma, targets CD38, a protein on myeloma and also on CD34+ hematopoietic progenitor cells. Because mobilized CD34+ cells are critical for stem cell transplant, we inves
Externí odkaz:
https://doaj.org/article/364a62290fbf4b409d7bc9bdc5e061ec
Autor:
Adin Kugelmass, Yamin Li, Denis Toskic, Qiaobing Xu, Ping Zhou, Ming Wang, Raymond Comenzo, Liu Yang, Xun Ma, Terry Fogaren, Melissa Warner, Lisa Lee, Amandeep Godara
Publikováno v:
Gene Therapy. 26:187-197
Patients with immunoglobulin (Ig) light-chain (LC) diseases such as LC light-chain amyloidosis die with organ failure and need new therapies. We sought a model to test anti-LC siRNA delivery to human plasma cells, requiring circulating LC, in vivo in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9869e2af4b247dff0e164436b146abf8
https://doi.org/10.1038/s41434-019-0070-y
https://doi.org/10.1038/s41434-019-0070-y
Autor:
Raymond L. Comenzo, Denis Toskic, Amandeep Godara, Heather Landau, Adin Kugelmass, Jack Albanese, Benjamin Rosenthal, Teresa Fogaren, Ping Zhou, Cindy Varga, Nauman S Siddiqui
Publikováno v:
Am J Hematol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae92c72c4f70303a5d3e218892f281f
https://doi.org/10.1002/ajh.26025
https://doi.org/10.1002/ajh.26025
Autor:
Teresa Fogaren, Ping Zhou, Benjamin Rosenthal, Adin Kugelmass, Amandeep Godara, Cindy Varga, Raymond L. Comenzo, Xun Ma, Denis Toskic
Publikováno v:
American journal of hematologyREFERENCES. 95(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac4135d06127066ecb83a6cfd1ffc22
https://pubmed.ncbi.nlm.nih.gov/31951032
https://pubmed.ncbi.nlm.nih.gov/31951032
Autor:
Kenneth B. Miller, Melissa Warner, Kellie Sprague, Andreas K. Klein, Sandy W. Wong, Xun Ma, Denis Toskic, Chakra P Chaulagain, Lisa Lee, Adin Kugelmass, Parul Doshi, Cindy Varga, Ping Zhou, Raymond Comenzo
Publikováno v:
Experimental Hematology & Oncology
Experimental Hematology & Oncology, Vol 7, Iss 1, Pp 1-10 (2018)
Experimental Hematology & Oncology, Vol 7, Iss 1, Pp 1-10 (2018)
Background The monoclonal antibody daratumumab, approved for treating myeloma, targets CD38, a protein on myeloma and also on CD34+ hematopoietic progenitor cells. Because mobilized CD34+ cells are critical for stem cell transplant, we investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22143d980b0b35f352b8b672698f2ba6
https://doi.org/10.1186/s40164-018-0119-4
https://doi.org/10.1186/s40164-018-0119-4
Autor:
Cindy Varga, Katelynn Ho, Raymond Comenzo, Teresa Fogaren, Lisa Xingguang Lee, Ping Zhou, Denis Toskic, Adin Kugelmass, Xun Ma, Melissa Warner
Publikováno v:
Amyloid. 26:101-102
In systemic AL amyloidosis treatment targeting the clonal plasma cells that produce the pathologic free light chain (FLC) can achieve FLC normalization, organ responses and improved survival. Howev...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ecb2cf8683e3942e745d4f4c5d83c8
https://doi.org/10.1080/13506129.2019.1600498
https://doi.org/10.1080/13506129.2019.1600498
Autor:
Ping Zhou, Cindy Varga, Benjamin Rosenthal, Teresa Fogaren, Adin Kugelmass, Raymond L. Comenzo, Denis Toskic, Amandeep Godara
Publikováno v:
Blood. 134:4409-4409
Introduction: Systemic light-chain (AL) amyloidosis results from clonal plasma cells that secrete toxic fibril-forming free light chains. Therapies directed at the plasma cell clone form the backbone of its management. Identification of cell-surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bea1da251228377bf71f707e6f384692
https://doi.org/10.1182/blood-2019-126988
https://doi.org/10.1182/blood-2019-126988
Autor:
Ping Zhou, Denis Toskic, Benjamin Rosenthal, Teresa Fogaren, Cindy Varga, Adin Kugelmass, Amandeep Godara, Raymond L. Comenzo
Publikováno v:
Blood. 134:4369-4369
Introduction: Response criteria in light-chain (AL) amyloidosis, revised in 2012, did not specify a depth of change in the pathologic involved FLC (iFLC) for either an amyloid complete response (aCR) or a very good partial response (VGPR) (JCO 2012;3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bfe10f214c852db97732b6ac0c9f92
https://doi.org/10.1182/blood-2019-127004
https://doi.org/10.1182/blood-2019-127004
Autor:
Denis Toskic, Amandeep Godara, Teresa Fogaren, Raymond L. Comenzo, Adin Kugelmass, Ping Zhou, Cindy Varga
Publikováno v:
Journal of Clinical Oncology. 37:8010-8010
8010 Background: In systemic AL amyloidosis (AL), caused by clonal Ig free light chains (LC) produced in 75% of cases by λ clones, patients often present with advanced organ damage, making earlier diagnosis a critical unmet need. Five λ IGLV germli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56a1ca583e4559eedc850b1f8e0cdeae
https://doi.org/10.1200/jco.2019.37.15_suppl.8010
https://doi.org/10.1200/jco.2019.37.15_suppl.8010
Autor:
Denis Toskic, Cindy Varga, Melissa Warner, Teresa Fogaren, Raymond L. Comenzo, Lisa X. Lee, Adin Kugelmass, Ping Zhou
Publikováno v:
Blood. 132:1903-1903
INTRODUCTION : Currently patients with systemic AL amyloidosis (AL) are not identified until they are sick due to end-organ damage, usually a result of elevated clonal Ig free light chains (FLC) produced by λ clones in 75% of cases. Delays in diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90937c7eaba1ff3b57a65738371031b3
https://doi.org/10.1182/blood-2018-99-112902
https://doi.org/10.1182/blood-2018-99-112902