Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Adil R. Sarhan"'
Publikováno v:
Biochemistry Research International, Vol 2021 (2021)
Several studies have demonstrated that age, comorbidities, and abnormalities in different clinical biomarkers can be important to understand disease severity. Although clinical features of COVID-19 have been widely described, the assessment of altera
Externí odkaz:
https://doaj.org/article/d03eda06c1ca4d8a98cb0a7da84cd7c0
Autor:
Adil R. Sarhan, Justyna Szyroka, Shabana Begum, Michael G. Tomlinson, Neil A. Hotchin, John K. Heath, Debbie L. Cunningham
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The Platelet Derived Growth Factor (PDGF) family of ligands have well established functions in the induction of cell proliferation and migration during development, tissue homeostasis and interactions between tumours and stroma. However, the
Externí odkaz:
https://doaj.org/article/0b0dbe9723e34b89ad5ea75b59b2f907
Publikováno v:
Biochemistry Research International, Vol 2021 (2021)
Biochemistry Research International
Biochemistry Research International
Several studies have demonstrated that age, comorbidities, and abnormalities in different clinical biomarkers can be important to understand disease severity. Although clinical features of COVID-19 have been widely described, the assessment of altera
Publikováno v:
SSRN Electronic Journal.
Several studies have demonstrated that age, comorbidities and abnormalities in different clinical biomarkers can be important to understand disease severity. Although clinical features of COVID-19 have been widely described, the assessment of alterat
The first patient with COVID-19 was reported in Iraq on 24 February 2020 for the Iranian student came from Iran. As of 24 May 2020, the confirmed cases of COVID-19 infections reached 4469, with 160 deaths and 2738 patients were recovered from the inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea3a5a9fba72fcc85d95d651a52bc91
https://doi.org/10.1101/2020.06.23.20138370
https://doi.org/10.1101/2020.06.23.20138370
Autor:
Helen J. Cooper, Katie Brookes, Andrew J. Creese, Harriet R. Ferguson, Hongyan Zhao, John K. Heath, Katherine P. B. Larkins, Anna A. Marusiak, Debbie L. Cunningham, Adil R. Sarhan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Fibroblast Growth Factor (FGF) dependent signalling is frequently activated in cancer by a variety of different mechanisms. However, the downstream signal transduction pathways involved are poorly characterised. Here a quantitative differential phosp
Autor:
Ying, Fan, Andrew J M, Howden, Adil R, Sarhan, Pawel, Lis, Genta, Ito, Terina N, Martinez, Kathrin, Brockmann, Thomas, Gasser, Dario R, Alessi, Esther M, Sammler
Publikováno v:
Biochemical Journal
Biochemical journal 475(1), 23-44 (2017). doi:10.1042/BCJ20170803
Biochemical journal 475(1), 23-44 (2017). doi:10.1042/BCJ20170803
The addition of phosphate groups to substrates allows protein kinases to regulate a myriad of biological processes, and contextual analysis of protein-bound phosphate is important for understanding how kinases contribute to physiology and disease. Le
Autor:
Herschel S. Dhekne, Elena Purlyte, Rachel C Gomez, Pawel Lis, Melanie Wightman, Adil R. Sarhan, Suzanne R. Pfeffer, Francesca Tonelli, Dario R. Alessi, Terina N. Martinez
Publikováno v:
The EMBO Journal
Parkinson's disease predisposing LRRK2 kinase phosphorylates a group of Rab GTPase proteins including Rab29, within the effector‐binding switch II motif. Previous work indicated that Rab29, located within the PARK16 locus mutated in Parkinson's pat
Autor:
Adil R, Sarhan, Justyna, Szyroka, Shabana, Begum, Michael G, Tomlinson, Neil A, Hotchin, John K, Heath, Debbie L, Cunningham
Publikováno v:
Scientific Reports
The Platelet Derived Growth Factor (PDGF) family of ligands have well established functions in the induction of cell proliferation and migration during development, tissue homeostasis and interactions between tumours and stroma. However, the mechanis