Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Adil J. Nazarali"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 5, Pp 832-850 (2019)
Externí odkaz:
https://doaj.org/article/b2584b484b924f83b2b976729aca03b9
Autor:
Paul P. R. Iyyanar, Adil J. Nazarali
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Cleft palate is one of the most common congenital birth defects worldwide. The homeobox (Hox) family of genes are key regulators of embryogenesis, with Hoxa2 having a direct role in secondary palate development. Hoxa2−/− mice exhibit cleft palate
Externí odkaz:
https://doaj.org/article/b18692dd8ee646c0b23ca230e347f973
Autor:
Dennis O. Okello, Paul P. R. Iyyanar, William M. Kulyk, Tara M. Smith, Scott Lozanoff, Shaoping Ji, Adil J. Nazarali
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Cleft palate is a common congenital abnormality that results from defective secondary palate (SP) formation. The Sine oculis-related homeobox 2 (Six2) gene has been linked to abnormalities of craniofacial and kidney development. Our current study exa
Externí odkaz:
https://doaj.org/article/ebcb3005b86949b2aa14106f185aaa79
Publikováno v:
Journal of Cellular and Molecular Medicine
SIRT2 is a NAD+‐dependent deacetylase that deacetylates a diverse array of protein substrates and is involved in many cellular processes, including regulation of inflammation. However, its precise role in the inflammatory process has not completely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc0e76f5eba9c9dde555550a1c1609a
http://europepmc.org/articles/PMC7339210
http://europepmc.org/articles/PMC7339210
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 5, Pp 832-850 (2019)
Background/aims Runt-related transcription factor 2 (Runx2) is a master regulator of osteogenic differentiation, but most of the direct downstream targets of RUNX2 during osteogenesis are unknown. Likewise, High-temperature requirement factor A1 (HTR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2323e8a8fa318585baf498c470f5a8d3
https://doi.org/10.33594/000000176
https://doi.org/10.33594/000000176
Autor:
Chu Zhang, Zichao Hu, Chen-Yu Zhang, Merlin P. Thangaraj, Ran Bi, Keyuan Chen, Kendra L Furber, Junjun Cheng, Na Fang, Adil J. Nazarali, Shaoping Ji
Publikováno v:
Cell Cycle
We have previously found that Sirt2 enhanced the outgrowth of cellular processes and MBP expression in CG4 cells, where Sirt2 expression is suppressed by transcription factor Nkx2.2. However, the detailed mechanism of Sirt2 facilitating oligodendrogl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f5b8ea7c500db5df22f6c2d3ff75e7
https://doi.org/10.1080/15384101.2019.1609818
https://doi.org/10.1080/15384101.2019.1609818
Autor:
Stuart Read, Merlin P. Thangaraj, Bogdan F. Gh. Popescu, Sally Caine, Richard P. Bazinet, Scott M. Rosendahl, Kendra L Furber, R.J. Scott Lacombe, Adil J. Nazarali
Publikováno v:
Neurochemical research. 47(3)
White matter degeneration in the central nervous system (CNS) has been correlated with a decline in cognitive function during aging. Ultrastructural examination of the aging human brain shows a loss of myelin, yet little is known about molecular and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4ad12dad9e19d7b061ad5e9908399f
https://pubmed.ncbi.nlm.nih.gov/34820737
https://pubmed.ncbi.nlm.nih.gov/34820737
Autor:
Yahui Wang, Adil J. Nazarali, Yang An, Fengling Wang, Wenqiang Wei, Weijuan Zhang, Shuzhen Wang, Xiangqian Guo, Shaoping Ji, Tingxuan Gu, Na Fang
Publikováno v:
Journal of Cellular and Molecular Medicine
PTEN is a tumour suppressor that is frequently mutated in a variety of cancers. Hence, PTEN has significant potential as a therapeutic molecule. PTEN‐long is an alternative translation variant, with an additional 173 amino acids added to the N‐te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3dacd35bd6ed1b239d4651123f98aa
https://doi.org/10.1111/jcmm.13236
https://doi.org/10.1111/jcmm.13236
Autor:
Shaoping Ji, Kendra L Furber, LaRhonda Sobchishin, Adil J. Nazarali, Merlin P. Thangaraj, Jotham K. Gan, J. Ronald Doucette
Publikováno v:
Journal of Biological Chemistry. 292:5166-5182
Myelination is controlled by timely expression of genes involved in the differentiation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes (OLs). Sirtuin 2 (SIRT2), a NAD+-dependent deacetylase, plays a critical role in OL di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc4c8f5cb6506d63fec9c021f2b81f9
https://doi.org/10.1074/jbc.m117.775544
https://doi.org/10.1074/jbc.m117.775544
Publikováno v:
The Open Biochemistry Journal. 9:37-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::155038a7963cf344b01f1c0c1fa9e0e4
https://doi.org/10.2174/1874091x20150609e001
https://doi.org/10.2174/1874091x20150609e001