Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adiam W. Bahta"'
Autor:
Muy-Teck Teh, Emilios Gemenetzidis, Deeviyaben Patel, Rameez Tariq, Ayesha Nadir, Adiam W Bahta, Ahmad Waseem, Iain L Hutchison
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34329 (2012)
The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regula
Externí odkaz:
https://doaj.org/article/482d49f1c0f34ebeb3d2ca3ea7b0f61d
Autor:
Markus M. Nöthen, Bryan Siu Yin Ho, Michael P. Philpott, Axel M. Hillmer, Yee Yen Sia, Paul L. Bigliardi, Elaine G.Y. Chew, Stefanie Heilmann, Joanna H.J. Tan, Xingliang Liu, Andrew C.A. Wan, Tze Chiun Lim, Adiam W. Bahta
Publikováno v:
Journal of Investigative Dermatology. 136:1559-1567
Androgenetic alopecia (AGA) is a common heritable and androgen-dependent hair loss condition in men. Twelve genetic risk loci are known to date, but it is unclear which genes at these loci are relevant for AGA. Dermal papilla cells (DPCs) located in
Autor:
Adiam W. Bahta, James H Upton, Rosalind F. Hannen, Bessam Farjo, Michael P. Philpott, Nilofer Farjo
Publikováno v:
Journal of Investigative Dermatology. 135:1244-1252
Dermal papilla cells (DPCs) taken from male androgenetic alopecia (AGA) patients undergo premature senescence in vitro in association with the expression of p16(INK4a), suggesting that DPCs from balding scalp are more sensitive to environmental stres
Autor:
Claudio Raimondi, Adiam W. Bahta, Danielle L. Lavery, C Ghimenti, Baki Akgül, Daniele Bergamaschi, Martin Hufbauer, Michael P. Philpott, Catherine A. Harwood, Sahira Khalaf, Kristin M. Braun, Rubeta N Matin, Anissa Chikh, Giovanna Chiorino, Paola Ostano, Valentina Senatore, Maurizia Mello-Grand
Publikováno v:
The EMBO Journal. 30:4261-4273
iASPP, an inhibitory member of the ASPP (apoptosis stimulating protein of p53) family, is an evolutionarily conserved inhibitor of p53 which is frequently upregulated in human cancers. However, little is known about the role of iASPP under physiologi
Autor:
Emilios Gemenetzidis, Iain Hutchison, Ahmad Waseem, Muy-Teck Teh, Adiam W. Bahta, Deeviyaben Patel, Rameez Tariq, Ayesha Nadir
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e34329 (2012)
PLoS ONE, Vol 7, Iss 3, p e34329 (2012)
The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regula
Autor:
Christos C. Zouboulis, Jacky M. Burrin, Wesley J. Harrison, Adiam W. Bahta, Louise E. Russell, Michael P. Philpott
Publikováno v:
Experimental dermatology. 16(10)
The nuclear receptors liver X receptor alpha (LXRalpha) and liver X-receptor beta (LXRbeta) have a well documented role in cholesterol homeostasis and lipid metabolism within tissues and cells including the liver, small intestine and macrophages. In
Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression
Publikováno v:
Journal of Investigative Dermatology. (5):1088-1094
Androgenetic alopecia (AGA), a hereditary disorder that involves the progressive thinning of hair in a defined pattern, is driven by androgens. The hair follicle dermal papilla (DP) expresses androgen receptors (AR) and plays an important role in the