Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Adi Vaknin"'
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Multiple sclerosis (MS) therapeutic goals have traditionally been dichotomized into two distinct avenues: immune-modulatory-centric interventions and pro-regenerative strategies. Oligodendrocyte progenitor cells (OPCs) were regard
Externí odkaz:
https://doaj.org/article/f3b0a8dabcaa40e0a58c3f1e48382179
Autor:
Ayal Rozenberg, Shahar Shelly, Adi Vaknin-Dembinsky, Tal Friedman-Korn, Tal Benoliel-Berman, Polina Spector, Natalya Yarovinsky, Diana Guber, Lilach Gutter Kapon, Yair Wexler, Esther Ganelin-Cohen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe presence of oligoclonal bands (OCBs) in cerebrospinal fluid (CSF) is a pivotal diagnostic marker for multiple sclerosis (MS). These bands play a crucial role in the diagnosis and understanding of a wide array of immune diseases. In th
Externí odkaz:
https://doaj.org/article/d10eac74c8594bdea077b87cae8dfe65
Autor:
Esther Ganelin‐Cohen, Chen Buxbaum, Noam Bosak, Shani Sobol, Adi Vaknin‐Dembinsky, Mark A Hellmann, Adi Wilf‐Yarkoni, Keren Regev, Elizaveta Pustovoyt, Alla Shifrin, Yair Wexler, Ayal Rozenberg
Publikováno v:
Brain and Behavior, Vol 14, Iss 7, Pp n/a-n/a (2024)
Abstract Introduction Examining the safety of theBNT162b2 mRNA vaccine in multiple sclerosis (MS) patients remains inconclusive, particularly regarding the potential for disease exacerbations. This study aims to assess the effects of BNT162b2 COVID
Externí odkaz:
https://doaj.org/article/83f6312cb48b48198f138f5ff81dad63
Autor:
Susanna Asseyer, Nasrin Asgari, Jeffrey Bennett, Omer Bialer, Yolanda Blanco, Francesca Bosello, Anna Camos-Carreras, Edgar Carnero Contentti, Sara Carta, John Chen, Claudia Chien, Mashina Chomba, Russell C. Dale, Josep Dalmau, Kristina Feldmann, Eoin P. Flanagan, Caroline Froment Tilikete, Carolina Garcia-Alfonso, Joachim Havla, Mark Hellmann, Ho Jin Kim, Philipp Klyscz, Frank Konietschke, Chiara La Morgia, Marco Lana-Peixoto, Maria Isabel Leite, Netta Levin, Michael Levy, Sara Llufriu, Pablo Lopez, Itay Lotan, Alessandra Lugaresi, Romain Marignier, Sara Mariotto, Susan P. Mollan, Cassandra Ocampo, Frederike Cosima Oertel, Maja Olszewska, Jacqueline Palace, Lekha Pandit, José Luis Peralta Uribe, Sean Pittock, Sudarshini Ramanathan, Natthapon Rattanathamsakul, Albert Saiz, Sara Samadzadeh, Bernardo Sanchez-Dalmau, Deanna Saylor, Michael Scheel, Tanja Schmitz-Hübsch, Jemal Shifa, Sasitorn Siritho, Pia S. Sperber, Prem S. Subramanian, Alon Tiosano, Adi Vaknin-Dembinsky, Alvaro Jose Mejia Vergara, Adi Wilf-Yarkoni, Luis Alfonso Zarco, Hanna G. Zimmermann, Friedemann Paul, Hadas Stiebel-Kalish
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Optic neuritis (ON) often occurs at the presentation of multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD). The recommended treatment of high-dos
Externí odkaz:
https://doaj.org/article/5f9ad39795f54fbf9171a0e0c490d165
Autor:
Tehila Mizrachi, Oshrit Marsha, Karen Brusin, Yael Ben-David, Ganesh A. Thakur, Adi Vaknin-Dembinsky, Millet Treinin, Talma Brenner
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background The α7 nicotinic acetylcholine receptor (α7 nAChR) negatively regulates the synthesis and release of pro-inflammatory cytokines by immune cells. Our previous studies showed that in encephalitogenic T cells, α7 nAChR expression
Externí odkaz:
https://doaj.org/article/6d24ca967cc946cb86c9711a2f608157
Autor:
Ariel Rechtman, Livnat Brill, Omri Zveik, Benjamin Uliel, Nitzan Haham, Atira S. Bick, Netta Levin, Adi Vaknin-Dembinsky
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundMyelin oligodendrocyte glycoprotein antibody disorders (MOGAD) have evolved as a distinct group of inflammatory, demyelinating diseases of the CNS. MOGAD can present with a monophasic or relapsing disease course with distinct clinical manif
Externí odkaz:
https://doaj.org/article/6979490d0ccf422fb81e1ba11ce97988
Autor:
Omri Zveik, Ariel Rechtman, Nitzan Haham, Irit Adini, Tamar Canello, Iris Lavon, Livnat Brill, Adi Vaknin-Dembinsky
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7117 (2022)
Neuromyelitis optica (NMO) is a rare disease usually presenting with bilateral or unilateral optic neuritis with simultaneous or sequential transverse myelitis. Autoantibodies directed against aquaporin-4 (AQP4-IgG) are found in most patients. They a
Externí odkaz:
https://doaj.org/article/52382768ea7e4809bd0cdb41968ab640
Autor:
Livnat Brill, Esther Ganelin-Cohen, Ron Dabby, Shira Rabinowicz, Efrat Zohar-Dayan, Netaniel Rein, Eyal Aloni, Yuval Karmon, Adi Vaknin-Dembinsky
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Introduction: Myelin oligodendrocyte glycoprotein (MOG) antibody associated disorders (MOGAD) have been recognized over the past 10 years as distinct inflammatory, demyelinating diseases of the central nervous system (CNS). Antibodies against MOG are
Externí odkaz:
https://doaj.org/article/330033f5252344aeb6bc32a4e5ac672c
Publikováno v:
Molecules, Vol 26, Iss 20, p 6139 (2021)
Nicotinic acetylcholine receptors (nAChRs) are widely expressed in or on various cell types and have diverse functions. In immune cells nAChRs regulate proliferation, differentiation and cytokine release. Specifically, activation of the α7 nAChR red
Externí odkaz:
https://doaj.org/article/8283b4285a7445dd8db25cd8efceef55
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: The clinical course of multiple sclerosis ranges from benign with little disease progression and minimal disability, to severe disease requiring intensive medical treatment. There are no reliable circulating biomarkers for predicting dise
Externí odkaz:
https://doaj.org/article/6db9b2d5bd5d4edc9fafcc75addeb1b7