Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Adi Moseri"'
Publikováno v:
The FEBS journalReferences. 289(11)
The N-terminal segment of CCR5 contains four tyrosine residues, sulphation of two of which is essential for high-affinity binding to gp120. In the present study, the interactions of gp120
Publikováno v:
The FEBS Journal. 285:4296-4310
Infection by HIV-1 requires protein-protein interactions involving gp120, CD4 and CCR5. We have previously demonstrated that the transferred nuclear Overhauser effect (TRNOE), in combination with asymmetric deuteration of a protein and a peptide liga
Autor:
Lewis E. Kay, Jacob Anglister, Brandon Fridman, Naama Kessler, Fred Naider, Leah S. Cohen, Adi Moseri, Damir Sakhapov, David Bolton, Sabine R. Akabayov
Publikováno v:
The FEBS journalReferences. 288(5)
The N-terminal segment of the chemokine receptor Human CC chemokine receptor 5 (CCR5), Nt-CCR5, contains four tyrosine residues, Y3, Y10, Y14, and Y15. Sulfation of at least two of these tyrosine residues was found to be essential for high-affinity b
Autor:
Gautam Srivastava, Sabine R. Akabayov, Fred Naider, Naama Kessler, Jacob Anglister, Adi Moseri, Boris Arshava
Publikováno v:
The FEBS Journal. 283:4084-4096
Weak protein-protein and protein-ligand interactions play important roles in biological recognition. In many cases, simplification of structural studies of large protein complexes is achieved by investigation of the interaction between the protein an
Autor:
Meital Abayev, Oren Tchaicheeyan, Jacob Anglister, Naama Kessler, Adi Moseri, Fred Naider, Tali Scherf, Boris Arshava
Publikováno v:
FEBS Journal. 282:1906-1921
C-C chemokine receptor 5 (CCR5) serves as a co-receptor for HIV-1. The CCR5 N-terminal segment, the second extracellular loop (ECL2) and the transmembrane helices have been implicated in binding the envelope glycoprotein gp120. Peptides corresponding
Publikováno v:
AIDS Research and Human Retroviruses. 29:718-724
Due to the different mechanisms HIV-1 has evolved to escape from a neutralizing antibody response it has been extremely challenging to develop an effective anti-HIV-1 vaccine. The V3 region of the gp120 HIV-1 envelope glycoprotein has been considered
Publikováno v:
Vaccine. 35(2)
V3-directed antibodies are present in practically all HIV-1 infected patients and in individuals vaccinated with gp120. The levels of maternal V3-directed antibodies were recently shown to correlate with reduced mother to child transmission, and V3 I
The peptide T20, which corresponds to a sequence in the C-terminal segment of the HIV-1 transmembrane glycoprotein gp41, is a strong entry inhibitor of HIV-1. It has been assumed that T20 inhibits HIV-1 infection by binding to the trimer formed by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351163db55944b8562537d5f0fd7047c
https://europepmc.org/articles/PMC4715528/
https://europepmc.org/articles/PMC4715528/
Publikováno v:
Journal of Virology. 78:4730-4743
The composite amplicon-6 vectors, which are derived from human herpesvirus 6 (HHV-6), can target hematopoietic cells. In the presence of the respective helper viruses, the amplicons are replicated by the rolling circle mechanism, yielding defective g