Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Adi Millman"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 4, p e1010694 (2023)
It has become clear in recent years that anti-phage defense systems cluster non-randomly within bacterial genomes in so-called "defense islands". Despite serving as a valuable tool for the discovery of novel defense systems, the nature and distributi
Externí odkaz:
https://doaj.org/article/b69e8a5627704c2fbe2399eed206f7c1
Autor:
Jeremy Garb, Anna Lopatina, Aude Bernheim, Mindaugas Zaremba, Virginijus Siksnys, Sarah Melamed, Azita Leavitt, Adi Millman, Gil Amitai, Rotem Sorek
Publikováno v:
Nature Microbiology. 7:1849-1856
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffafdb595dd52803c109a4bc8f1ef356
https://doi.org/10.1038/s41564-022-01207-8
https://doi.org/10.1038/s41564-022-01207-8
Autor:
Francois Rousset, Erez Yirmiya, Shahar Nesher, Alexander Brandis, Tevie Mehlman, Maxim Itkin, Sergey Malitsky, Adi Millman, Sarah Melamed, Rotem Sorek
SummaryDuring viral infection, cells can deploy immune strategies that deprive viruses of molecules essential for their replication. In this study, we report a family of immune effectors in bacteria which, in response to phage infection, degrade cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b69114cf8e4968d06e7faa16538f37b9
https://doi.org/10.1101/2023.01.24.525353
https://doi.org/10.1101/2023.01.24.525353
Autor:
Maya Baroz, Shany Doron, Daniel B. A. Malheiro, Adi Millman, Ehud Herbst, Nitzan Tal, Gal Ofir, Daniel Cohen, Sergey Malitsky, Gil Amitai, Rotem Sorek
Publikováno v:
Nature. 600:116-120
The Toll/interleukin-1 receptor (TIR) domain is a canonical component of animal and plant immune systems1,2. In plants, intracellular pathogen sensing by immune receptors triggers their TIR domains to generate a molecule that is a variant of cyclic A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341be98e1e62e9fcaa64595915227cb9
https://doi.org/10.1038/s41586-021-04098-7
https://doi.org/10.1038/s41586-021-04098-7
Autor:
Avigail Stokar-Avihail, Taya Fedorenko, Jeremy Garb, Azita Leavitt, Adi Millman, Gabriela Shulman, Nicole Wojtania, Sarah Melamed, Gil Amitai, Rotem Sorek
Over the past few years, numerous anti-phage defense systems have been discovered in bacteria. While the mechanism of defense for some of these systems is understood, a major unanswered question is how these systems sense phage infection. To systemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e652f2e651139376317b50422c9467fe
https://doi.org/10.1101/2022.08.27.505566
https://doi.org/10.1101/2022.08.27.505566
Autor:
Brianna Duncan-Lowey, Nitzan Tal, Alex G. Johnson, Shaun Rawson, Megan L. Mayer, Shany Doron, Adi Millman, Sarah Melamed, Taya Fedorenko, Assaf Kacen, Gil Amitai, Rotem Sorek, Philip J. Kranzusch
SummaryRADAR is a two-protein bacterial defense system which was reported to defend against phage by ‘editing’ messenger RNA. Here we determine cryo-EM structures of the RADAR defense complex, revealing RdrA as a heptameric, two-layered AAA+ ATPa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::517163ced1057ca0d47f415f233c25c2
https://doi.org/10.1101/2022.08.17.504323
https://doi.org/10.1101/2022.08.17.504323
In recent years it has become clear that anti-phage defence systems cluster non-randomly within bacterial genomes in so-called “defence islands”. Despite serving as a valuable tool for the discovery of novel defence systems, the nature and distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::646ae1fdef3f94a786898a344461e722
https://doi.org/10.1101/2022.06.09.495481
https://doi.org/10.1101/2022.06.09.495481
Autor:
Avigail Stokar-Avihail, Taya Fedorenko, Jens Hör, Jeremy Garb, Azita Leavitt, Adi Millman, Gabriela Shulman, Nicole Wojtania, Sarah Melamed, Gil Amitai, Rotem Sorek
Publikováno v:
Cell. 186:1863-1876.e16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d096cc8bcb425fc9409ca64911ae0f0
https://doi.org/10.1016/j.cell.2023.02.029
https://doi.org/10.1016/j.cell.2023.02.029
Autor:
Brianna Duncan-Lowey, Nitzan Tal, Alex G. Johnson, Shaun Rawson, Megan L. Mayer, Shany Doron, Adi Millman, Sarah Melamed, Taya Fedorenko, Assaf Kacen, Alexander Brandis, Tevie Mehlman, Gil Amitai, Rotem Sorek, Philip J. Kranzusch
Publikováno v:
Cell. 186:987-998.e15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a64619e4c067911c17a1a2b22b26cb
https://doi.org/10.1016/j.cell.2023.01.012
https://doi.org/10.1016/j.cell.2023.01.012
Autor:
Adi Millman, Sarah Melamed, Azita Leavitt, Shany Doron, Aude Bernheim, Jens Hör, Jeremy Garb, Nathalie Bechon, Alexander Brandis, Anna Lopatina, Gal Ofir, Dina Hochhauser, Avigail Stokar-Avihail, Nitzan Tal, Saar Sharir, Maya Voichek, Zohar Erez, Jose Lorenzo M. Ferrer, Daniel Dar, Assaf Kacen, Gil Amitai, Rotem Sorek
Publikováno v:
Cell hostmicrobe. 30(11)
Bacterial anti-phage systems are frequently clustered in microbial genomes, forming defense islands. This property enabled the recent discovery of multiple defense systems based on their genomic co-localization with known systems, but the full arsena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0988127990418605f7389097b5f3f8
https://pubmed.ncbi.nlm.nih.gov/36302390
https://pubmed.ncbi.nlm.nih.gov/36302390