Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Adi D. Sabag"'
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The semaphorin guidance factors receptor plexin-A2 transduces sema6A and sema6B signals and may mediate, along with plexin-A4, the anti-angiogenic effects of sema6A. When associated with neuropilins plexin-A2 also transduces the anti-angioge
Externí odkaz:
https://doaj.org/article/332a7cf8a9764c0d81fb1e487d8adc0f
Autor:
Zufit Hexner-Erlichman, Maria Veiga-da-Cunha, Yoav Zehavi, Zahava Vadasz, Adi D. Sabag, Sameh Tatour, Ronen Spiegel
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundGlycogen storage disease type 1b (GSD1b) is an ultra-rare autosomal recessive disorder, caused by mutations in SLC37A4 gene. Affected patients present with episodes of fasting hypoglycemia and lactic acidosis, hepatomegaly, growth retardati
Externí odkaz:
https://doaj.org/article/9ddd4db544c94b418be2850a58e52445
Autor:
Jacob Bejar, Ofra Kessler, Adi D. Sabag, Edmond Sabo, Ofer Ben Itzhak, Gera Neufeld, Zahava Vadasz
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
BackgroundThe immune regulatory properties of semaphorin3A (sema3A) (both innate and adaptive) are well established in many in vitro studies. The injection of sema3A into a mice model of rheumatoid arthritis was proven to be highly beneficial, both i
Externí odkaz:
https://doaj.org/article/257c8c6c4a37417f8b106d933e88f25d
Publikováno v:
Journal of autoimmunity. 134
CD72 is a regulatory co-receptor on B cells, with a role in the pathogenesis of systemic lupus erythematosus (SLE) in both human and animal models. Semaphorin3A (sema3A) is a secreted member of the semaphorin family that can reconstruct B cells' regu
Autor:
Zufit, Hexner-Erlichman, Maria, Veiga-da-Cunha, Yoav, Zehavi, Zahava, Vadasz, Adi D, Sabag, Sameh, Tatour, Ronen, Spiegel
Publikováno v:
Frontiers in pediatrics, Vol. 10, no.-, p. 1071464 (2022)
BackgroundGlycogen storage disease type 1b (GSD1b) is an ultra-rare autosomal recessive disorder, caused by mutations in SLC37A4 gene. Affected patients present with episodes of fasting hypoglycemia and lactic acidosis, hepatomegaly, growth retardati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5d744dd6060518bd2c28546860b3ec
https://hdl.handle.net/2078.1/271398
https://hdl.handle.net/2078.1/271398
Semaphorin3A (sema3A) inhibits the activity of B and T cells in autoimmune diseases such as Systemic Lupus Erythematosus (SLE). We have now found that CD72 functions as a novel sema3A binding and signal-transducing receptor. These functions of CD72 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::befae90bca4afec526ae104aa0efeb1d
https://doi.org/10.1101/2021.08.24.457482
https://doi.org/10.1101/2021.08.24.457482
SUMMARYThe semaphorin guidance factors receptor Plexin-A2 transduces sema6A and sema6B signals and when associated with neuropilins can also transduce sema3C signals. Inhibition of plexin-A2 expression in U87MG glioblastoma cells resulted in strong i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc028445f008b347fb7bb6e845929270
https://doi.org/10.1101/2021.07.12.452132
https://doi.org/10.1101/2021.07.12.452132
Publikováno v:
Immunologic Research. 66:649-654
The presence of T regulatory cells (Tregs) is highly required in normal skin in order to maintain immune tolerance to commensal microbes and to prevent the development of immune-mediated inflammation. Psoriasis is a chronic inflammatory skin disease
Autor:
Ofra Kessler, Edmond Sabo, Jacob Bejar, Adi D. Sabag, Gera Neufeld, Zahava Vadasz, Ofer Ben Itzhak
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Background: The immune regulatory properties of semaphorin3A (sema3A) (both innate and adaptive) are well established in many in-vitro studies. The injection of sema3A into a mice model of rheumatoid arthritis was proven to be highly beneficial, both
Publikováno v:
Semaphorins ISBN: 9784431543848
The semaphorins constitute a large family of secreted and membrane-bound proteins that were initially characterized as axon-guidance factors. In addition, several semaphorins, such as sema3B, sema3E, sema3F, sema4D, and a few additional less studied,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fdbafb54009500ee32eaddda4e3f285
https://doi.org/10.1007/978-4-431-54385-5_6
https://doi.org/10.1007/978-4-431-54385-5_6