Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Adhikarimayum Lakhikumar Sharma"'
Autor:
Joseph Hokello, Kratika Tyagi, Richard Oriko Owor, Adhikarimayum Lakhikumar Sharma, Alok Bhushan, Rene Daniel, Mudit Tyagi
Publikováno v:
Life, Vol 14, Iss 1, p 104 (2024)
The theory of immune regulation involves a homeostatic balance between T-helper 1 (Th1) and T-helper 2 (Th2) responses. The Th1 and Th2 theories were introduced in 1986 as a result of studies in mice, whereby T-helper cell subsets were found to direc
Externí odkaz:
https://doaj.org/article/b41ca3bb00774d4da081ae9df16a110e
Autor:
Adhikarimayum Lakhikumar Sharma, Puyam Milan Meitei, Takhellambam Chanu Machathoibi, Naorem Tarundas Singh, Thiyam Ramsing Singh, Lisam Shanjukumar Singh
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background We have previously reported that a new intronless gene for casein kinase 2α (CK2α), CSNK2A3, is expressed in human cells. The promoter of the well-known CK2α, CSNK2A1, displays characteristics of a housekeeping gene, whereas CS
Externí odkaz:
https://doaj.org/article/2a46272d81f84795bc38ad9a2c65b1bd
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105651- (2022)
Summary: The productive infection of HIV, which generates new viral progeny, depends on the activation status of the cell. In this study, we found cocaine exposure sensitizes partially active CD4+ T cells and makes them poised for productive HIV infe
Externí odkaz:
https://doaj.org/article/9d15fb7a40c64b3f825b78bbbaaffba5
Publikováno v:
Viruses, Vol 15, Iss 6, p 1362 (2023)
HIV-exposed seronegative individuals (HESIs) are a small fraction of persons who are multiply exposed to human immunodeficiency virus (HIV), but do not exhibit serological or clinical evidence of HIV infection. In other words, they are groups of peop
Externí odkaz:
https://doaj.org/article/aa40887604544d23a8cb1a27ec706aad
Autor:
Shilpa Sonti, Kratika Tyagi, Amit Pande, Rene Daniel, Adhikarimayum Lakhikumar Sharma, Mudit Tyagi
Publikováno v:
Vaccines, Vol 10, Iss 2, p 202 (2022)
Drug abuse is a common comorbidity in people infected with HIV. HIV-infected individuals who abuse drugs are a key population who frequently experience suboptimal outcomes along the HIV continuum of care. A modest proportion of HIV-infected individua
Externí odkaz:
https://doaj.org/article/3f2e007f24544a29a0eef54981a31250
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1272 (2021)
The central nervous system (CNS) is highly compartmentalized and serves as a specific site of human immunodeficiency virus (HIV) infection. Therefore, an understanding of the cellular populations that are infected by HIV or that harbor latent HIV pro
Externí odkaz:
https://doaj.org/article/4fb52a8409f74b18b4d04eb47c5caf09
Publikováno v:
Pathogens, Vol 10, Iss 7, p 806 (2021)
Unsafe sex with HIV-infected individuals remains a major route for HIV transmission, and protective strategies, such as the distribution of free condoms and pre-or post-prophylaxis medication, have failed to control the spread of HIV, particularly in
Externí odkaz:
https://doaj.org/article/2a7498fc058547dfab22390a9a9dc988
Publikováno v:
Vaccines, Vol 9, Iss 6, p 605 (2021)
In 2020, the global prevalence of human immunodeficiency virus (HIV) infection was estimated to be 38 million, and a total of 690,000 people died from acquired immunodeficiency syndrome (AIDS)–related complications. Notably, around 12.6 million peo
Externí odkaz:
https://doaj.org/article/9539e6a4ab7149cdbcc0053c456ce460
Autor:
Adhikarimayum Lakhikumar Sharma, Joseph Hokello, Shilpa Sonti, Sonia Zicari, Lin Sun, Aseel Alqatawni, Michael Bukrinsky, Gary Simon, Ashok Chauhan, Rene Daniel, Mudit Tyagi
Publikováno v:
Viruses, Vol 12, Iss 9, p 1040 (2020)
The C-promoter binding factor-1 (CBF-1) is a potent and specific inhibitor of the human immunodeficiency virus (HIV)-1 LTR promoter. Here, we demonstrate that the knockdown of endogenous CBF-1 in latently infected primary CD4+ T cells, using specific
Externí odkaz:
https://doaj.org/article/fcd19571f2874c4a9971417e4a521764
Publikováno v:
Viruses, Vol 12, Iss 8, p 868 (2020)
Human immunodeficiency virus type-1 (HIV-1) can either undergo a lytic pathway to cause productive systemic infections or enter a latent state in which the integrated provirus remains transcriptionally silent for decades. The ability to latently infe
Externí odkaz:
https://doaj.org/article/8d684489923e416abfa5e25dcabcc702