A review on the biology and management of potato tuber moth

Autor: Adhikari Aakash, Oli Dipiza, Pokhrel Ashim, Dhungana Babita, Paudel Bipul, Pandit Shishir, Bigyan G C, Dhakal Apurba

Publikováno v: Agriculture, Vol 68, Iss 3, Pp 97-109 (2022)

The potato tuber moth (PTM; caused by Phthorimaea operculella) is one of the most serious insect pests that causes damage to crop production and storage of potatoes. It causes damage to the potato, while larvae of P. operculella feed on and grow in t

Externí odkaz: https://doaj.org/article/85181f8ec6da4abba0786aded02a5b8b

N1 -Benzyl Tryptamine Pan-SHIP1/2 Inhibitors: Synthesis and Preliminary Biological Evaluation as Anti-Tumor Agents.

Autor: Fernandes S; Department of Microbiology & Immunology, SUNY Upstate Medical University, Syracuse, NY 13210, USA., Meyer ST; Department of Chemistry, Syracuse University, Syracuse, NY 13244, USA., Shah JP; Department of Chemistry, Syracuse University, Syracuse, NY 13244, USA., Adhikari AA; Department of Chemistry, Syracuse University, Syracuse, NY 13244, USA., Kerr WG; Department of Microbiology & Immunology, SUNY Upstate Medical University, Syracuse, NY 13210, USA., Chisholm JD; Department of Chemistry, Syracuse University, Syracuse, NY 13244, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 02; Vol. 27 (23). Date of Electronic Publication: 2022 Dec 02.

Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury.

Autor: Li DK; Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Chaudhari SN; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Lee Y; Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Sojoodi M; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Adhikari AA; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Zukerberg L; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Shroff S; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Barrett SC; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Tanabe K; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Chung RT; Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Devlin AS; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.

Publikováno v: Science advances [Sci Adv] 2022 Aug 26; Vol. 8 (34), pp. eabo2794. Date of Electronic Publication: 2022 Aug 26.

A microbial metabolite remodels the gut-liver axis following bariatric surgery.

Autor: Chaudhari SN; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Luo JN; Laboratory for Surgical and Metabolic Research, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Harris DA; Laboratory for Surgical and Metabolic Research, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Aliakbarian H; Laboratory for Surgical and Metabolic Research, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Yao L; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Paik D; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Subramaniam R; Laboratory for Surgical and Metabolic Research, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Adhikari AA; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Vernon AH; Laboratory for Surgical and Metabolic Research, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Kiliç A; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Program in Molecular Integrative Physiological Sciences, Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA., Huh JR; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Sheu EG; Laboratory for Surgical and Metabolic Research, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: esheu@bwh.harvard.edu., Devlin AS; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address: sloan_devlin@hms.harvard.edu.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2021 Mar 10; Vol. 29 (3), pp. 408-424.e7. Date of Electronic Publication: 2021 Jan 11.

Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis.

Autor: Pedicone C; Department of Microbiology & Immunology, SUNY Upstate Medical University, Syracuse, NY 13210, USA., Fernandes S; Department of Microbiology & Immunology, SUNY Upstate Medical University, Syracuse, NY 13210, USA., Dungan OM; Department of Chemistry, Syracuse University, Syracuse, NY 13210, USA., Dormann SM; Department of Chemistry, Syracuse University, Syracuse, NY 13210, USA., Viernes DR; Department of Chemistry, Syracuse University, Syracuse, NY 13210, USA., Adhikari AA; Department of Chemistry, Syracuse University, Syracuse, NY 13210, USA., Choi LB; Department of Chemistry, Syracuse University, Syracuse, NY 13210, USA., De Jong EP; Proteomics and Mass Spectrometry Core Facility, SUNY Upstate Medical University, Syracuse, NY, 13210, USA., Chisholm JD; Department of Chemistry, Syracuse University, Syracuse, NY 13210, USA., Kerr WG; Department of Microbiology & Immunology, SUNY Upstate Medical University, Syracuse, NY 13210, USA kerrw@upstate.edu.; Department of Chemistry, Syracuse University, Syracuse, NY 13210, USA.; Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY 13210, USA.

Publikováno v: Journal of cell science [J Cell Sci] 2020 Jan 10; Vol. 133 (5). Date of Electronic Publication: 2020 Jan 10.