Výsledky vyhledávání - "Adhiambo M. A. Witlox"

Impairment of Cyclo-oxygenase-2 Function Results in Abnormal Growth Plate Development and Bone Microarchitecture but Does Not Affect Longitudinal Growth of the Long Bones in Skeletally Immature Mice

Autor: Tim J. M. Welting, Tessy M. R. Castermans, Lodewijk W. van Rhijn, Adhiambo M. A. Witlox, M.M. Caron, Bert van Rietbergen, Mirella J. J. Haartmans

Publikováno v: Cartilage
Cartilage, 12(3), 387-398. SAGE Publications Inc.
Cartilage, 12(3), 387-398. SAGE Publications Ltd

Objective Despite the general awareness that cyclo-oxygenase-2 (COX-2) is crucial for endochondral ossification, the role of COX-2 in skeletal development is largely unknown. We hypothesized that inhibition or genetic loss of COX-2 leads to impaired

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb109d994ef3e6b2d4fae69455ede2b1
https://doi.org/10.1177/1947603519833149

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Evaluation of impaired growth plate development of long bones in skeletally immature mice by antirheumatic agents

Autor: Mirella J. J. Haartmans, Lodewijk W. van Rhijn, Tim J. M. Welting, Bert van Rietbergen, M.M. Caron, Adhiambo M. A. Witlox, Tessy M. R. Castermans

Publikováno v: Journal of Orthopaedic Research, 39(3), 553-564. Wiley
Journal of Orthopaedic Research

Restriction of physical growth and development is a known problem in patients with juvenile idiopathic arthritis (JIA). However, the effect of medical treatment for JIA on skeletal growth in affected children has not been properly investigated. We, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b60e1a019d84f82797da3bb47280d0
https://research.tue.nl/nl/publications/8cbdeddf-3c06-4cc0-a127-2f624cbffa81

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Caron_et_al._Supplemental_data_Revision – Supplemental material for Impairment of Cyclo-oxygenase-2 Function Results in Abnormal Growth Plate Development and Bone Microarchitecture but Does Not Affect Longitudinal Growth of the Long Bones in Skeletally Immature Mice

Autor: Caron, Marjolein M. J., Castermans, Tessy M. R., Rietbergen, Bert Van, Haartmans, Mirella J. J., Rhijn, Lodewijk W. Van, Adhiambo M. A. Witlox, Welting, Tim J. M.

Supplemental material, Caron_et_al._Supplemental_data_Revision for Impairment of Cyclo-oxygenase-2 Function Results in Abnormal Growth Plate Development and Bone Microarchitecture but Does Not Affect Longitudinal Growth of the Long Bones in Skeletall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05fa7ddb2c2bb5bb074a6c7cd0cabc5

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Anti-rheumatic agents naproxen and methotrexate affect skeletal development in skeletally immature mice

Autor: B. van Rietbergen, Adhiambo M. A. Witlox, Tessy M. R. Castermans, L.W. van Rhijn, M.M. Caron, Mirella J. J. Haartmans, T.J. Welting

Publikováno v: Osteoarthritis and Cartilage. 26:S80

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09adf9a76f0f6faa91bbb017c8aba3a5
https://doi.org/10.1016/j.joca.2018.02.171

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Current Knowledge on Exostoses Formation in Hereditary Multiple Exostoses: Where do Exostoses Originate and in What Way is their Growth Regulated

Autor: Tim J. M. Welting, Pieter J. Emans, Heleen M. Staal, Adhiambo M. A. Witlox, L.W. van Rhijn, D.T. Mooij, J.S.J. Ham

Publikováno v: Hereditary Genetics, 3(3):134. Longdom Group SA

Multiple hereditary exostoses is an autosomal dominant inherited disease causing exostoses: growth on the bones of children. The disease is mainly caused by mutated exostosin (EXT)-1 or EXT-2 genes. These mutations yield non-functional EXT-gene produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bff0d26eef5016b3090ca329ec11fc
https://doi.org/10.4172/2161-1041.1000134

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