Ferulic acid interventions ameliorate NDEA-CCl 4 -induced hepatocellular carcinoma via Nrf2 and p53 upregulation and Akt/PKB-NF-κB-TNF-α pathway downregulation in male Wistar rats.

Autor: Somade OT; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Ajayi BO; Department of Chemical Sciences, Faculty of Natural Sciences, Ajayi Crowther University, Oyo, Nigeria., Adeyi OE; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Dada TA; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Ayofe MA; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Inalu DC; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Ajiboye OI; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Shonoiki OM; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Adelabu AO; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Onikola RT; Key Laboratory of Green Process and Engineering, State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China., Isiaka ID; Center for Bacteria and Viruses Resources and Bioinformation, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China., Omotoso O; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., James AS; School of Biomedical Sciences, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Olaniyan TO; Instituto Politécnico Nacional, Centro de Biotecnologĭa Genómica, Reynosa 88710, Mexico., Adegoke AM; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan 200005, Nigeria., Akamo AJ; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Oyinloye BE; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, PMB, 5454, Ado-Ekiti 360001, Nigeria., Adewole E; Industrial Chemistry Unit, Department of Chemical Sciences, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.

Publikováno v: Toxicology reports [Toxicol Rep] 2024 Jan 14; Vol. 12, pp. 119-127. Date of Electronic Publication: 2024 Jan 14 (Print Publication: 2024).

Effect of syringic acid on steroid and gonadotropic hormones, hematological indices, sperm characteristics and morphologies, and markers of tissue damage in methyl cellosolve-administered rats.

Autor: Somade OT; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria.; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, PMB 5454, Ado-Ekiti, 360001, Nigeria., Oyinloye BE; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, PMB 5454, Ado-Ekiti, 360001, Nigeria.; Institute of Drug Research and Development, S.E Bogoro Center, Afe Babalola University, PMB 5454, Ado-Ekiti, 360001, Nigeria.; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, 3886, South Africa., Ajiboye BO; Institute of Drug Research and Development, S.E Bogoro Center, Afe Babalola University, PMB 5454, Ado-Ekiti, 360001, Nigeria.; Phytomedicine and Molecular Toxicology Research Laboratory, Department of Biochemistry, Federal University Oye Ekiti, Oye, Ekiti State, Nigeria., Osukoya OA; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, PMB 5454, Ado-Ekiti, 360001, Nigeria., Adeyi OE; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria.

Publikováno v: Biochemistry and biophysics reports [Biochem Biophys Rep] 2022 Oct 07; Vol. 32, pp. 101360. Date of Electronic Publication: 2022 Oct 07 (Print Publication: 2022).

Moringa oleifera Extract Extenuates Echis ocellatus Venom-Induced Toxicities, Histopathological Impairments and Inflammation via Enhancement of Nrf2 Expression in Rats.

Autor: Adeyi AO; Animal Physiology Unit, Department of Zoology, University of Ibadan, Ibadan P.M.B. 200284, Oyo State, Nigeria., Adeyemi SO; Animal Physiology Unit, Department of Zoology, University of Ibadan, Ibadan P.M.B. 200284, Oyo State, Nigeria., Effiong EP; Animal Physiology Unit, Department of Zoology, University of Ibadan, Ibadan P.M.B. 200284, Oyo State, Nigeria., Ajisebiola BS; Department of Zoology, Osun State University, Oshogbo P.M.B. 230212, Osun State, Nigeria., Adeyi OE; Department of Biochemistry, Federal University of Agriculture, Abeokuta P.M.B. 2240, Ogun State, Nigeria., James AS; Department of Biochemistry, Federal University of Agriculture, Abeokuta P.M.B. 2240, Ogun State, Nigeria.

Publikováno v: Pathophysiology : the official journal of the International Society for Pathophysiology [Pathophysiology] 2021 Mar 05; Vol. 28 (1), pp. 98-115. Date of Electronic Publication: 2021 Mar 05.

Oxidative stress-mediated induction of pulmonary oncogenes, inflammatory, and apoptotic markers following time-course exposure to ethylene glycol monomethyl ether in rats.

Autor: Somade OT; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Ajayi BO; Department of Chemical Sciences, Faculty of Natural Sciences, Ajayi Crowther University, Oyo, Nigeria., Adeyi OE; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Adeshina AA; School of Medicine, All Saints University, Roseau, Dominica., Adekoya MO; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria., Abdulhameed RO; Department of Biochemistry, College of Biosciences, Federal University of Agriculture, Abeokuta, Nigeria.

Publikováno v: Metabolism open [Metabol Open] 2020 Dec 15; Vol. 9, pp. 100075. Date of Electronic Publication: 2020 Dec 15 (Print Publication: 2021).

Thyroid and reproductive hormones disruption as well as kallikrein-3 level in dimethyl nitrosamine-induced toxicity: Effects of ascorbate treatment in male wistar rats.

Autor: Somade OT; Department of Biochemistry, College of Biosciences, Federal University of Agriculture Abeokuta, Abeokuta, Nigeria., Ugbaja RN; Department of Biochemistry, College of Biosciences, Federal University of Agriculture Abeokuta, Abeokuta, Nigeria., Adeyi OE; Department of Biochemistry, College of Biosciences, Federal University of Agriculture Abeokuta, Abeokuta, Nigeria., Ogunberu DM; Department of Biochemistry, College of Biosciences, Federal University of Agriculture Abeokuta, Abeokuta, Nigeria.

Publikováno v: Biochimie open [Biochim Open] 2016 Sep 28; Vol. 3, pp. 40-46. Date of Electronic Publication: 2016 Sep 28 (Print Publication: 2016).