Zobrazeno 1 - 10 of 85 pro vyhledávání: '"Adewola A"'
1
Akademický článek
Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA
Autor: Tuan Nguyen, Sai Li, Jeremy T-H Chang, John W. Watters, Htet Ng, Adewola Osunsade, Yael David, Shixin Liu
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here the authors used single-molecule imaging and manipulation to study the mechanical effects of transcription factor Sox2 co-condensation with DNA and chromatin. They found that Sox2 condensates exert a high level of mechanical stress on DNA, but t
Externí odkaz: https://doaj.org/article/a5fc41cecb574669a410977790cd6293
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2
Akademický článek
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
Autor: Qingfei Zheng, Adewola Osunsade, Yael David
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Protein arginine deiminase 4 (PAD4) facilitates the posttranslational citrullination of histones H3 and H4. Here, the authors provide evidence that PAD4 antagonizes histone methylglyoxal-glycation by rewriting the glycated arginine into citrulline an
Externí odkaz: https://doaj.org/article/fced30f35c3c4c4fa7ad21938c03dc03
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3
Akademický článek
Reversible histone glycation is associated with disease-related changes in chromatin architecture
Autor: Qingfei Zheng, Nathaniel D. Omans, Rachel Leicher, Adewola Osunsade, Albert S. Agustinus, Efrat Finkin-Groner, Hannah D’Ambrosio, Bo Liu, Sarat Chandarlapaty, Shixin Liu, Yael David
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Proteins continuously undergo non-enzymatic modifications such as glycation, which accumulate under physiological conditions but can be enhanced in disease. Here the authors characterise histone glycation, provide evidence that it affects chromatin,
Externí odkaz: https://doaj.org/article/d549df8147a043739d0eb71b8d597555
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4
Single-stranded nucleic acid binding and coacervation by linker histone H1
Autor: Rachel Leicher, Adewola Osunsade, Gabriella N. L. Chua, Sarah C. Faulkner, Andrew P. Latham, John W. Watters, Tuan Nguyen, Emily C. Beckwitt, Sophia Christodoulou-Rubalcava, Paul G. Young, Bin Zhang, Yael David, Shixin Liu
Publikováno v: Nat Struct Mol Biol
The H1 linker histone family is the most abundant group of eukaryotic chromatin-binding proteins. However, their contribution to chromosome structure and function remains incompletely understood. Here we use single-molecule fluorescence and force mic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13d9511e093efc8eba43aa873cd6fbc
https://europepmc.org/articles/PMC9117509/
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5
Akademický článek
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7
Wound Healing Activities of Latex of Grassleaf Spurge (Euphobia graminea Jacq.)
Autor: J M Adelowo, A E Morakinyo, Orimolade O.O, O O Adewola, S O Babarinde, A O Bolaji, O D Oladimeji, B A Akinpelu, Oyedapo O. O
Publikováno v: American Journal of Biomedical Research. 8:63-71
The present study evaluated the wound healing potentials of E. graminea (EG) latex. The latex of EG was screened for the presence of phytochemical constituents; in vitro antioxidant property and erythrocyte membrane stabilizing activity was used to i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a0aafdcdd5b918a5766db1686527802
https://doi.org/10.12691/ajbr-8-3-2
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