Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Adewale Adegbuyiro"'
Autor:
Adewale Adegbuyiro, Alyssa R. Stonebraker, Faezeh Sedighi, Caleb K. Fan, Breanna Hodges, Peng Li, Stephen J. Valentine, Justin Legleiter
Publikováno v:
Biochemistry. 61:1517-1530
Expansion of a polyglutamine (polyQ) domain within the first exon of the huntingtin (htt) protein is the underlying cause of Huntington's disease, a genetic neurodegenerative disorder. PolyQ expansion triggers htt aggregation into oligomers, fibrils,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9e6976fb98f280548a80ee088e779a
https://doi.org/10.1021/acs.biochem.2c00212
https://doi.org/10.1021/acs.biochem.2c00212
Autor:
Faezeh Sedighi, Adam Skeens, Adewale Adegbuyiro, John Bard, Chathuranga Siriwardhana, Emily Donley, Werner J. Geldenhuys, Justin Legleiter
Huntingtin disease (HD) is a neurodegenerative disease caused by expansion of a polyglutamine (polyQ) tract within the huntingtin (htt) protein, leading to aggregation into a variety of species ranging from small oligomers to large fibrils. A consens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2910e1b78fc078f300616fa912c251d1
https://doi.org/10.1101/2023.03.01.530665
https://doi.org/10.1101/2023.03.01.530665
Publikováno v:
ACS Chemical Neuroscience. 11:328-343
Huntington's disease (HD), a genetic neurodegenerative disease, is caused by an expanded polyglutamine (polyQ) domain in the first exon of the huntingtin protein (htt). PolyQ expansion destabilizes protein structure, resulting in aggregation into a v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8635080013b449d0d69f2dcbf4b931e3
https://doi.org/10.1021/acschemneuro.9b00509
https://doi.org/10.1021/acschemneuro.9b00509
Autor:
Caleb K. Fan, Justin Legleiter, Sharon E. Groover, Maryssa Beasley, Katelyn Taylor, Adewale Adegbuyiro, Breanna L. Hodges, Chathuranga Siriwardhana, Alyssa R. Stonebraker
Publikováno v:
Colloids Surf B Biointerfaces
Huntington’s disease (HD) is a fatal neurodegenerative disease caused by an extended polyglutamine (polyQ) domain within the first exon of the huntingtin protein (htt). PolyQ expansion directly invokes the formation of a heterogenous mixture of tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7502d71cd85bf5c0322a2b25b82721d
https://europepmc.org/articles/PMC8429182/
https://europepmc.org/articles/PMC8429182/
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a9e670d825db6f2a3ea0d61df1c7b90
https://doi.org/10.1096/fasebj.2021.35.s1.03970
https://doi.org/10.1096/fasebj.2021.35.s1.03970
Autor:
Justin Legleiter, Pranav Jain, Faezeh Sedighi, Mark V. Pinti, Chathuranga Siriwardhana, John M. Hollander, Adewale Adegbuyiro
Publikováno v:
Biochim Biophys Acta Biomembr
Huntington’s disease (HD) is a neurodegenerative disease caused by the expansion of a polyglutamine (polyQ) tract near the N-terminus of the huntingtin (htt) protein. Expanded polyQ tracts are prone to aggregate into oligomers and insoluble fibrils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573453a06113319ed13006ea9eeffc21
https://doi.org/10.1016/j.bbamem.2021.183663
https://doi.org/10.1016/j.bbamem.2021.183663
Autor:
Adewale Adegbuyiro, Louis M. Nwokocha
Publikováno v:
African Journal of Pure and Applied Chemistry. 11:19-29
The industrial application of a vegetable oil is determined by the oil properties. This work was undertaken to alter the properties of Jatropha curcas Kernel oil and possibly find new applications for it. The seed kernels were roasted to different te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50d07b8c8af95a24d75437436fa11100
https://doi.org/10.5897/ajpac2017.0721
https://doi.org/10.5897/ajpac2017.0721
Publikováno v:
Biophysical Journal. 118:216a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac26c8eff7d690a48e1df464b67669e9
https://doi.org/10.1016/j.bpj.2019.11.1286
https://doi.org/10.1016/j.bpj.2019.11.1286
Publikováno v:
Biophysical Journal. 118:540a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6b06fe53e2983ddbfd5e612a420463
https://doi.org/10.1016/j.bpj.2019.11.2958
https://doi.org/10.1016/j.bpj.2019.11.2958
Autor:
Sharon E. Groover, Adewale Adegbuyiro, Justin Legleiter, Faezeh Sedighi, Albert W. Pilkington
Several hereditary neurological and neuromuscular diseases are caused by an abnormal expansion of trinucleotide repeats. To date, there have been ten of these trinucleotide repeat disorders associated with an expansion of the codon CAG encoding gluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588414cce1c8284bfbbf1e5a3d3d624d
https://europepmc.org/articles/PMC5727916/
https://europepmc.org/articles/PMC5727916/