Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

Autor: Bliss, CM, Drammeh, A, Bowyer, G, Sanou, GS, Jagne, YJ, Ouedraogo, O, Edwards, NJ, Tarama, C, Ouedraogo, N, Ouedraogo, M, Njie-Jobe, J, Diarra, A, Afolabi, MO, Tiono, AB, Yaro, JB, Adetifa, UJ, Hodgson, SH, Anagnostou, NA, Roberts, R, Duncan, CJA, Cortese, R, Viebig, NK, Leroy, O, Lawrie, AM, Flanagan, KL, Kampmann, B, Imoukhuede, EB, Sirima, SB, Bojang, K, Hill, AVS, Nebie, I, Ewer, KJ

Publikováno v: Molecular Therapy

Heterologous prime-boosting with viral vectors encoding the pre-erythrocytic antigen thrombospondin-related adhesion protein fused to a multiple epitope string (ME-TRAP) induces CD8+ T cell-mediated immunity to malaria sporozoite challenge in Europea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::71a1ea9acc0321e0c0b0f33915d31e0e

Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants.

Autor: Afolabi MO; Medical Research Council Unit, Fajara, The Gambia., Tiono AB; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Adetifa UJ; Medical Research Council Unit, Fajara, The Gambia., Yaro JB; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Drammeh A; Medical Research Council Unit, Fajara, The Gambia., Nébié I; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Bliss C; The Jenner Institute Laboratories, University of Oxford, Oxford, UK., Hodgson SH; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, UK., Anagnostou NA; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, UK., Sanou GS; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Jagne YJ; Medical Research Council Unit, Fajara, The Gambia., Ouedraogo O; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Tamara C; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Ouedraogo N; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Ouedraogo M; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Njie-Jobe J; Medical Research Council Unit, Fajara, The Gambia., Diarra A; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso., Duncan CJ; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, UK., Cortese R; Keires AG, Bäumleingasse, Basel, Switzerland., Nicosia A; ReiThera, Rome, Italy.; CEINGE, Naples, Italy.; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy., Roberts R; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, UK., Viebig NK; European Vaccine Initiative, UniversitätsKlinikum Heidelberg, Heidelberg, Germany., Leroy O; European Vaccine Initiative, UniversitätsKlinikum Heidelberg, Heidelberg, Germany., Lawrie AM; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, UK., Flanagan KL; Medical Research Council Unit, Fajara, The Gambia.; Current address: Department of Immunology, Monash University, Prahran, Melbourne, Australia., Kampman B; Medical Research Council Unit, Fajara, The Gambia., Bejon P; Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya., Imoukhuede EB; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, UK., Ewer KJ; The Jenner Institute Laboratories, University of Oxford, Oxford, UK., Hill AV; The Jenner Institute Laboratories, University of Oxford, Oxford, UK.; Centre for Clinical Vaccinology and Tropical Medicine, The Jenner Institute, Churchill Hospital, Oxford, UK., Bojang K; Medical Research Council Unit, Fajara, The Gambia., Sirima SB; Centre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2016 Aug; Vol. 24 (8), pp. 1470-7. Date of Electronic Publication: 2016 Apr 25.

The tuberculin skin test (TST) is affected by recent BCG vaccination but not by exposure to non-tuberculosis mycobacteria (NTM) during early life.

Autor: Burl S; Infant Immunology, Medical Research Council UK The Gambia, Fajara, The Gambia. sburl0712@gmail.com, Adetifa UJ, Cox M, Touray E, Whittle H, McShane H, Rowland-Jones SL, Flanagan KL

Publikováno v: PloS one [PLoS One] 2010 Aug 19; Vol. 5 (8), pp. e12287. Date of Electronic Publication: 2010 Aug 19.