PPARγ depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation

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Hypoxia stimulates pulmonary hypertension (PH) in part by increasing the proliferation of pulmonary vascular wall cells. Recent evidence suggests that signaling events involved in hypoxia-induced cell proliferation include sustained nuclear factor-ka

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2bb0fc628f21a8dadb3d5fdd67a2a0b9
https://europepmc.org/articles/PMC4355175/

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Chronic Hypoxia Promotes Pulmonary Artery Endothelial Cell Proliferation through H2O2-Induced 5-Lipoxygenase.

Autor: Porter, Kristi M., Kang, Bum-Yong, Adesina, Sherry E., Murphy, Tamara C., Hart, C. Michael, Sutliff, Roy L.

Publikováno v: PLoS ONE; Jun2014, Vol. 9 Issue 6, p1-9, 9p

Zinc Deficiency: A Potential Hidden Driver of the Detrimental Cycle of Chronic Kidney Disease and Hypertension.

Autor: Ume AC; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine, College of Science and Mathematics, Wright State University, Dayton, Ohio., Wenegieme TY; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine, College of Science and Mathematics, Wright State University, Dayton, Ohio., Adams DN; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine, College of Science and Mathematics, Wright State University, Dayton, Ohio., Adesina SE; Division of Pulmonary Medicine, Department of Medicine, Emory University, Atlanta, Georgia., Williams CR; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine, College of Science and Mathematics, Wright State University, Dayton, Ohio.

Publikováno v: Kidney360 [Kidney360] 2023 Mar 01; Vol. 4 (3), pp. 398-404.