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U6 snRNA m6A modification is required for accurate and efficient cis- and trans-splicing of C. elegans mRNAs.

Autor: Shen A; School of Biological Sciences, University of East Anglia, NR4 7TJ, Norwich., Hencel K; School of Biological Sciences, University of East Anglia, NR4 7TJ, Norwich.; These authors contributed equally., Parker MT; School of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.; These authors contributed equally., Scott R; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Skukan R; School of Biological Sciences, University of East Anglia, NR4 7TJ, Norwich., Adesina AS; School of Biological Sciences, University of East Anglia, NR4 7TJ, Norwich., Metheringham CL; School of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, UK., Miska EA; Wellcome/CRUK Gurdon Institute, University of Cambridge, Tennis Court Rd, Cambridge, CB2 1QN, UK., Nam Y; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA., Haerty W; School of Biological Sciences, University of East Anglia, NR4 7TJ, Norwich.; Earlham Institute, Norwich Research Park, Norwich, UK., Simpson GG; School of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.; Cell & Molecular Sciences, James Hutton Institute, Invergowrie, DD2 5DA, UK., Akay A; School of Biological Sciences, University of East Anglia, NR4 7TJ, Norwich.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 16. Date of Electronic Publication: 2023 Sep 16.