Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aderonke Ajayi-Smith"'
Autor:
Stefano Cacciatore, Martha Wium, Cristina Licari, Aderonke Ajayi-Smith, Lorenzo Masieri, Chanelle Anderson, Azola Samkele Salukazana, Lisa Kaestner, Marco Carini, Giuseppina M. Carbone, Carlo V. Catapano, Massimo Loda, Towia A. Libermann, Luiz F. Zerbini
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Background Men with African ancestry are more likely to develop aggressive prostate cancer (PCa) and to die from this disease. The study of PCa in the South African population represents an opportunity for biomedical research due to the high
Externí odkaz:
https://doaj.org/article/455b5f98b8da4e75a5af428d053f1584
Autor:
Sarah Carden, Pauline van der Watt, Alicia Chi, Aderonke Ajayi-Smith, Katie Hadley, Virna D. Leaner
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Karyopherin β1 (Kpnβ1) is the main nuclear import protein involved in the transport of cargoes from the cytoplasm into the cell nucleus. Previous research has found Kpnβ1 to be significantly overexpressed in cervical cancer and
Externí odkaz:
https://doaj.org/article/8330bcca21324bae838e08fb24794131
Autor:
Nonkululeko Mkwanazi, John O. Trent, Aderonke Ajayi-Smith, Virna D. Leaner, Pauline J. van der Watt, Sarah Carden
Publikováno v:
Experimental cell research. 404(2)
Karyopherin beta 1 (Kpnβ1) is a major nuclear import receptor that mediates the import of cellular cargoes into the nucleus. Recently it has been shown that Kpnβ1 is highly expressed in several cancers, and its inhibition by siRNA induces apoptotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96fe12a651bca960eb02a81d98f38bc3
https://pubmed.ncbi.nlm.nih.gov/34019908
https://pubmed.ncbi.nlm.nih.gov/34019908
Publikováno v:
Critical reviews in eukaryotic gene expression. 29(5)
Transcription factors control numerous cellular processes, including proliferation, apoptosis, differentiation, and inflammation. Abnormal transcription factor activity has been implicated in a variety of diseases, especially cancer. The correct subc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3937162316b63c21fef740127085d5d
https://pubmed.ncbi.nlm.nih.gov/32421998
https://pubmed.ncbi.nlm.nih.gov/32421998
Autor:
Carden, Sarah, Watt, Pauline Van Der, Chi, Alicia, Aderonke Ajayi-Smith, Hadley, Katie, Leaner, Virna
Figure S3. p53 and p21 inhibition reduces and enhances CaSki EGFP and Kpnβ1-EGFP cell sensitivity to Cisplatin, respectively. A: CaSki EGFP (a) and Kpnβ1-EGFP (b) cells were co-treated with Cisplatin and the p53 inhibitor Pifithrin α, and cell pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0cd29acd215e97aa6618b073905abf
Autor:
Carden, Sarah, Watt, Pauline Van Der, Chi, Alicia, Aderonke Ajayi-Smith, Hadley, Katie, Leaner, Virna
Figure S2. Overexpression of Kpnβ1 results in increased sensitivity to Cisplatin. Dose-response curves are shown after treatment of HeLa EGFP- and HeLa Kpnβ1-EGF-expressing cells with Cisplatin. (PPTX 42 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f870481d98f184aa96242c1008e8e2
Autor:
Carden, Sarah, Watt, Pauline Van Der, Chi, Alicia, Aderonke Ajayi-Smith, Hadley, Katie, Leaner, Virna
Figure S1. Overexpression of Kpnβ1 results in changes in the morphology and adhesion properties of CaSki cervical cancer cells. A: Phase contrast images showing CaSki EGFP and Kpnβ1-EGFP cells, taken 48 h post plating. Cells were viewed at 20 x mag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a59bcad4c7d798ac7cae68d22a372f1