Výsledky vyhledávání

Oncolytic Viruses: a novel treatment strategy for breast cancer

Autor: Mohammad Javanbakht, Sanaz Tahmasebzadeh, Luca Cegolon, Nasrin Gholami, Mandana Kashaki, Hassan Nikoueinejad, Mohamad Mozafari, Mahsa Mozaffari, Shi Zhao, Mostafa Khafaei, Morteza Izadi, Saeid Fathi, Reza Akhavan-Sigari

Breast cancer, an unceasingly occurring neoplasm, is one of the major determinants of mortality in women. Several ineffective attempts have been pursued using with conventional therapies against breast cancer. Resistance to existing therapies and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd5770daffcfc95ef3b9d7b809dcded
https://www.sciencedirect.com/science/article/pii/S2352304221001616

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Combination of dl922-947 Oncolytic Adenovirus and G-Quadruplex Binders Uncovers Improved Antitumor Activity in Breast Cancer

Autor: Fabiana Napolitano, Sarah Di Somma, Giuliano Castellano, Jussara Amato, Bruno Pagano, Antonio Randazzo, Giuseppe Portella, Anna Maria Malfitano

Publikováno v: Cells; Volume 11; Issue 16; Pages: 2482

G-quadruplexes (G4s) are nucleic secondary structures characterized by G-tetrads. G4 motif stabilization induces DNA damage and cancer cell death; therefore, G4-targeting small molecules are the focus of clinical investigation. DNA destabilization in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d91a358d3798966adfb9ed1aef6bc6
http://hdl.handle.net/11588/896199

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Clinical and Epidemiologic Features of Viral Gastroenteritis in Hospitalized Children: An 11-Year Surveillance in Palermo (Sicily)

Autor: Emanuele Amodio, Simona De Grazia, Dario Genovese, Floriana Bonura, Chiara Filizzolo, Antonella Collura, Francesca Di Bernardo, Giovanni M. Giammanco

Publikováno v: Viruses; Volume 15; Issue 1; Pages: 41

In order to acquire information regarding viral agents and epidemiologic features of severe paediatric Viral Acute Gastroenteritis (VAGE) across multiple seasons in the pre-rotavirus-vaccine era, the epidemiologic characteristics of VAGE were investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e8823c530df8aacb01be0eeb4d723f
https://doi.org/10.3390/v15010041

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Adenoviral gene transfer of a single‐chain IL‐23 induces psoriatic arthritis–like symptoms in NOD mice

Autor: Christopher H. Evans, Jing Zhao, Consuelo M. Lopez De Padilla, Matthew J. Yousefzadeh, Montina Van Meter, Nam Vo, Lei Zhang, Lana Carbo, Andrea Gambotto, Enrico Pola, Luise A. Angelini, Laura J. Niedernhofer, Eun Kim, Debora Colangelo, Paul D. Robbins, Rafael Flores

Publikováno v: FASEB J

Previously, we demonstrated that intratumoral delivery of adenoviral vector encoding single-chain (sc)IL-23 (Ad.scIL-23) was able to induce systemic antitumor immunity. Here, we examined the role of IL-23 in diabetes in nonobese diabetic mice. Intrav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b8b08d1a62f82a15d00aa612bef1c4
https://doi.org/10.1096/fj.201900420r

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Findings from Studies Are Congruent with Obesity Having a Viral Origin, but What about Obesity-Related NAFLD?

Autor: Giovanni Tarantino, Vincenzo Citro, Mauro Cataldi

Publikováno v: Viruses, Vol 13, Iss 1285, p 1285 (2021)
Viruses

Infection has recently started receiving greater attention as an unusual causative/inducing factor of obesity. Indeed, the biological plausibility of infectobesity includes direct roles of some viruses to reprogram host metabolism toward a more lipog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa6ba3a49857745d450a95466f675c6
https://www.mdpi.com/1999-4915/13/7/1285

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Desenvolvimento de adenovírus recombinantes expres-sando as glicoproteínas F e G do metapneumovírus aviário (aMPV) e do vírus respiratório sincicial bo-vino(bRSV)

Autor: Silva, Luciana Helena Antoniassi da, 1977

Publikováno v: Biblioteca Digital de Teses e Dissertações da Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP

Orientadores: Clarice Weis Arns, Fernando Rosado Spilki Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia Resumo: Os membros da família Paramyxoviridae são vírus que causam infecções em humanos e animais de importância

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d739135f3ece57278c82802740207ec4
https://doi.org/10.47749/t/unicamp.2013.908227

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Integrated Use of Molecular Techniques to Detect and Genetically Characterise DNA Viruses in Italian Wolves (Canis lupus italicus)

Autor: Andrea Balboni, Giuseppe Lucifora, Alessia Terrusi, Giuseppe Merialdi, Lorenza Urbani, Carmela Musto, Maria Cristina Fontana, Francesco Dondi, Mara Battilani, Mauro Delogu

Publikováno v: Animals
Volume 11
Issue 8
Animals, Vol 11, Iss 2198, p 2198 (2021)

In this study, internal organs (tongue, intestine, and spleen) of 23 free-ranging Italian wolves (Canis lupus italicus) found dead between 2017 and 2019 were tested for Carnivore protoparvovirus 1, Canine adenovirus (CAdV), and Canine circovirus (Can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a26722a61605a750f0b92e1a3b64b46
http://hdl.handle.net/11585/857109

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Potential diagnostic and prognostic biomarkers for adenovirus respiratory infection in children and young adults

Autor: Sara Scarpini, Sugitha Sureshkumar, Giovanni Battista Biserni, Carlotta Biagi, Luca Pierantoni, Alessandro Rocca, Marcello Lanari, Arianna Dondi, Riccardo Masetti

Publikováno v: Viruses
Viruses, Vol 13, Iss 1885, p 1885 (2021)

Human Adenoviruses (HAdV) are known to be potentially associated with strong inflammatory responses and morbidity in pediatric patients. Although most of the primary infections are self-limiting, the severity of clinical presentation, the elevation o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca27f96a3e70df8d8002bc699b5c4ae
https://hdl.handle.net/11585/851781

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Immune Response against Adenovirus in Acute Upper Respiratory Tract Infections in Immunocompetent Children

Autor: Andrea Pession, Francesca Conti, Arianna Dondi, Ada Dormi, Jessica Bandini, Giovanni Battista Biserni, Marcello Lanari, Riccardo Masetti

Publikováno v: Vaccines, Vol 8, Iss 602, p 602 (2020)
Vaccines
Volume 8
Issue 4

During acute upper respiratory tract infections (AURTIs) caused by Adenoviruses, the mix of severe clinical presentation, together with elevation of white blood cells (WBCs) and C-reactive protein (CRP), often mimicking bacterial infection, leads to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f62c6331239c2a8dc362c9b5d9f5125
https://www.mdpi.com/2076-393X/8/4/602

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