Zobrazeno 1 - 10
of 6 130
pro vyhledávání: '"Adenosine receptors"'
Autor:
Kaijing Yang, Xiaoli Shan, Yang Songru, Mengwei Fu, Pei Zhao, Wei Guo, Ming Xu, Huihua Chen, Rong Lu, Chen Zhang
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 456-471 (2024)
AbstractContext The mechanisms of Traditional Chinese Medicine (TCM) Guizhi-Gancao Decoction (GGD) remain unknown.Objective This study explores the mechanisms of GGD against cardiac hypertrophy.Materials and methods Network pharmacology analysis was
Externí odkaz:
https://doaj.org/article/6728d85a12f04b75b38cea3e1f12361f
Autor:
Longsheng Wang, Jie Zhang, Wenxin Zhang, Mingming Zheng, Hongjie Guo, Xiaohui Pan, Wen Li, Bo Yang, Ling Ding
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 1951-1964 (2024)
Adenosine (Ado) is significantly elevated in the tumor microenvironment (TME) compared to normal tissues. It binds to adenosine receptors (AdoRs), suppressing tumor antigen presentation and immune cell activation, thereby inhibiting tumor adaptive im
Externí odkaz:
https://doaj.org/article/47c85988398546b29c2f6ccb59e34f4c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Extracellular ATP and its derivates mediate a signaling pathway that might be pharmacologically targeted to treat inflammatory conditions. Extracellular adenosine, the product of ATP hydrolysis by ectonucleotidase enzymes, plays a key role in halting
Externí odkaz:
https://doaj.org/article/de9144486c3b4cec9e941bb161a56d5f
Autor:
Mi-Hyeon Jang, Juhyun Song
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116996- (2024)
Metabolic syndromes (e.g., obesity) are characterized by insulin resistance, chronic inflammation, impaired glucose metabolism, and dyslipidemia. Recently, patients with metabolic syndromes have experienced not only metabolic problems but also neurop
Externí odkaz:
https://doaj.org/article/f21ff08e53d942848f7fcbf007fe54f3