Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Adenosine A1 receptors"'
Autor:
Tao Chen, Ling Cheng, Jingwen Ma, Jiyuan Yuan, Chao Pi, Linjin Xiong, Jinglin Chen, Huiyang Liu, Jia Tang, Yueting Zhong, Xiaomei Zhang, Zerong Liu, Ying Zuo, Hongping Shen, Yumeng Wei, Ling Zhao
Publikováno v:
Pharmacological Research, Vol 194, Iss , Pp 106837- (2023)
Major depressive disorder (MDD) is a chronic relapsing psychiatric disorder. Conventional antidepressants usually require several weeks of continuous administration to exert clinically significant therapeutic effects, while about two-thirds of the pa
Externí odkaz:
https://doaj.org/article/24e5b1ac74d34cfd96295e5f646328c5
Publikováno v:
Basic and Clinical Neuroscience, Vol 11, Iss 3, Pp 333-348 (2020)
Introduction: In this study, the role of A1 adenosine receptors in improving the effect of Low-Frequency Electrical Stimulation (LFS) on seizure-induced hyperexcitability of hippocampal CA1 pyramidal neurons was investigated. Methods: A semi-rapid hi
Externí odkaz:
https://doaj.org/article/d8f4a9d860f34379b106c7174d8b7574
Autor:
Zhao-Hui Chen, Yuan-Yuan Han, Ying-Jie Shang, Si-Yi Zhuang, Jun-Ni Huang, Bao-Yan Wu, Chu-Hua Li
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Cordycepin exerted significant neuroprotective effects and protected against cerebral ischemic damage. Learning and memory impairments after cerebral ischemia are common. Cordycepin has been proved to improve memory impairments induced by cerebral is
Externí odkaz:
https://doaj.org/article/23c66a5c433b4094943bc145b8376806
Leucine-Enriched Essential Amino Acids Enhance the Antiseizure Effects of the Ketogenic Diet in Rats
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The classic ketogenic diet (KD) can be used successfully to treat medically refractory epilepsy. However, the KD reduces seizures in 50–70% of patients with medically refractory epilepsy, and its antiseizure effect is limited. In the current study,
Externí odkaz:
https://doaj.org/article/588cba0bb54d486b8224f1a0ab986255
Akademický článek
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Autor:
Yulan Li, Lixuan Li, Jintao Wu, Zhenggang Zhu, Xiang Feng, Liming Qin, Yuwei Zhu, Li Sun, Yijun Liu, Zilong Qiu, Shumin Duan, Yan-Qin Yu
Publikováno v:
eLife, Vol 9 (2020)
Astrocytes respond to and regulate neuronal activity, yet their role in mammalian behavior remains incompletely understood. Especially unclear is whether, and if so how, astrocyte activity regulates contextual fear memory, the dysregulation of which
Externí odkaz:
https://doaj.org/article/5eab8477e623401189ba87a21c52c207
Autor:
Barbara Kosmowska, Jadwiga Wardas
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1813 (2021)
Essential tremor (ET) is one of the most common neurological disorders that often affects people in the prime of their lives, leading to a significant reduction in their quality of life, gradually making them unable to independently perform the simpl
Externí odkaz:
https://doaj.org/article/d9d6c29c57b54de388fde68a36e9e1f5
Autor:
Mariachiara Zuccarini, Catia Lambertucci, Marzia Carluccio, Patricia Giuliani, Maurizio Ronci, Andrea Spinaci, Rosaria Volpini, Renata Ciccarelli, Patrizia Di Iorio
Publikováno v:
Cells, Vol 10, Iss 12, p 3560 (2021)
Adenosine A1 receptor (A1R) activation, stimulating lipogenesis and decreasing insulin resistance, could be useful for metabolic syndrome management in obese subjects. Since full A1R agonists induce harmful side-effects, while partial agonists show a
Externí odkaz:
https://doaj.org/article/eadce9d5aa25496ea2a74c68af0bc765
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 8 (2018)
Adenosine receptors (AR) are a family of G-protein coupled receptors, comprised of four members, named A1, A2A, A2B, and A3 receptors, found widely distributed in almost all human body tissues and organs. To date, they are known to participate in a l
Externí odkaz:
https://doaj.org/article/11c39902a38941e0933f0821b16e1bb0