Preliminary study on the occurrence of PTEN and PIK3CA gene mutations in endometrial cancer among Malaysian women

Autor: Zahurin Mohamed, Mat Adenan Na, Ivy Chung, Wong Ms, Yin Ling Woo, K S Subramaniam

Publikováno v: Scopus-Elsevier

Genetic mutations in endometrial cancer (EC) have been extensively studied in the Western population but not much in Asian cohorts. This study has demonstrated that PTEN and PIK3CA mutations are commonly found in EC among Malaysian women. Following R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7049de8e8e6366e2460232ba6c995f3
http://www.scopus.com/inward/record.url?eid=2-s2.0-84893191429&partnerID=MN8TOARS

Corrigendum to "Aberrant upregulation of CDK1 contributes to medroxyprogesterone acetate (MPA) resistance in cancer-associated fibroblasts of the endometrium" [Biochem. Biophys. Res. Commun. 628 (2022) 133-140].

Autor: Omar IS; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia; Universiti Malaya Cancer Research Institute, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Mat Adenan NA; Department of Obstetrics and Gynaecology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia; Department of Obstetrics and Gynaecology, Ara Damansara and Subang Jaya Medical Center, Ramsay Sime Darby Health Care, 47500, Subang Jaya, Selangor, Malaysia., Godoy A; Centro de Biología Celular y Biomedicina, Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile; Department of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, United States., Teo IH; Department of Obstetrics and Gynaecology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Gunasagran Y; Department of Obstetrics and Gynaecology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Chung I; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia; Universiti Malaya Cancer Research Institute, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address: ivychung@ummc.edu.my.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Jan 15; Vol. 640, pp. 202. Date of Electronic Publication: 2022 Dec 31.

MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling.

Autor: Omar IS; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.; Universiti Malaya Cancer Research Institute, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia., Abd Jamil AH; Department of Pharmaceutical Life Sciences, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur, Malaysia., Mat Adenan NA; Department of Obstetrics and Gynaecology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.; Department of Obstetrics and Gynaecology, Ara Damansara and Subang Jaya Medical Center, Ramsay Sime Darby Health Care, Subang Jaya, Selangor, Malaysia., Chung I; Department of Pharmacology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.; Department of Pharmaceutical Life Sciences, Faculty of Pharmacy, Universiti Malaya, Kuala Lumpur, Malaysia.

Publikováno v: PloS one [PLoS One] 2022 Jul 11; Vol. 17 (7), pp. e0270830. Date of Electronic Publication: 2022 Jul 11 (Print Publication: 2022).

Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women.

Autor: Lawrenson K; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Suite 290W, Los Angeles, CA, USA; Center for Bioinformatics and Functional Genomics, Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Electronic address: kate.lawrenson@cshs.org., Song F; National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; Department of Epidemiology and Biostatistics, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China., Hazelett DJ; Center for Bioinformatics and Functional Genomics, Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Kar SP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Tyrer J; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Phelan CM; Department of Gynecologic Oncology, Moffitt Cancer Center, Tampa, FL, USA; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA., Corona RI; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Suite 290W, Los Angeles, CA, USA; Center for Bioinformatics and Functional Genomics, Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Rodríguez-Malavé NI; Center for Bioinformatics and Functional Genomics, Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Seo JH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Adler E; Department of Preventive Medicine, University of Southern California, Keck School of Medicine, 1450 Biggy Street, Los Angeles, CA, USA., Coetzee SG; Center for Bioinformatics and Functional Genomics, Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Segato F; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, 14049-900, Brazil., Fonseca MAS; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, 14049-900, Brazil., Amos CI; Institute for Clinical and Translational Research, Department of Medicine, Baylor School of Medicine, Houston,TX, USA., Carney ME; Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA., Chenevix-Trench G; Genetics and Computational Biology Department, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD 4006, Australia., Choi J; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea; Department of Biomedical Science, Graduate School, Seoul National University, Seoul, Republic of Korea., Doherty JA; Jon M. and Karen Huntsman Endowed Associate Professor in Cancer Research Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, USA., Jia W; State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong 510060, China., Jin GJ; ShanghaiBio Corporation, Shanghai, China; CloudHealth Genomics Ltd, Shanghai, China., Kim BG; Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Republic of Korea., Le ND; Cancer Control Research, BC Cancer Agency, Vancouver, BC, Canada., Lee J; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Department of Biomedical Science, Graduate School, Seoul National University, 103 Daehak-ro, Jongno-gu, Seoul 110-799, Republic of Korea., Li L; National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; Department of Epidemiology and Biostatistics, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China., Lim BK; The Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Adenan NA; The Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Mizuno M; Department of Gynecological Oncology, Aichi Cancer Center Hospital, Japan., Park B; Department of Preventive Medicine, College of Medicine, Hanyang, Seoul, Republic of Korea., Pearce CL; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA., Shan K; Department of Obstetrics and Gynaecology,Hebei Medical University, Fourth Hospital, Shijiazhuang, China., Shi Y; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Sieh W; Department of Population Health Science and Policy, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Thompson PJ; Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Wilkens LR; Cancer Epidemiology Program, University of Hawaii Cancer Center, HI, USA., Wei Q; Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai 200032, China; Duke Cancer Institute, Duke University Medical Center, Durham, NC 27710, USA., Woo YL; The Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Yan L; Department of Molecular Biology, Hebei Medical University, Fourth Hospital, Shijiazhuang, China., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Suite 290W, Los Angeles, CA, USA., Freedman ML; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Noushmehr H; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, 14049-900, Brazil; Department of Neurosurgery, Henry Ford Health System, Detroit, MI, USA., Goode EL; Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA., Berchuck A; Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA., Sellers TA; Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA., Teo SH; Cancer Research Initiatives Foundation, Subang Jaya, Selangor, Malaysia., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Matsuo K; Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Japan., Park S; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea; Department of Biomedical Science, Graduate School, Seoul National University, Seoul, Republic of Korea., Chen K; National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; Department of Epidemiology and Biostatistics, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China., Pharoah PDP; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, UK., Gayther SA; Center for Bioinformatics and Functional Genomics, Cedars Sinai Genomics Core, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Goodman MT; Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Community and Population Health Research Institute, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Publikováno v: Gynecologic oncology [Gynecol Oncol] 2019 May; Vol. 153 (2), pp. 343-355. Date of Electronic Publication: 2019 Mar 19.

Embryo culture conditions are significantly improved during uninterrupted incubation: A randomized controlled trial.

Autor: Alhelou Y; Fakih IVF, Sh Haza Bin Zayed st, Abu Dhabi, United Arab Emirates; IVF Lab, Deparment of Obstetrics and Gynaecology, KKWK, UMMC, Faculty of Medicine, University of Malaya, K. Lumpur, Malaysia., Mat Adenan NA; IVF Lab, Deparment of Obstetrics and Gynaecology, KKWK, UMMC, Faculty of Medicine, University of Malaya, K. Lumpur, Malaysia., Ali J; IVF Lab, Deparment of Obstetrics and Gynaecology, KKWK, UMMC, Faculty of Medicine, University of Malaya, K. Lumpur, Malaysia. Electronic address: jaffarali.abdullah@gmail.com.

Publikováno v: Reproductive biology [Reprod Biol] 2018 Mar; Vol. 18 (1), pp. 40-45. Date of Electronic Publication: 2017 Dec 24.