Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Ademola Famurewa"'
1
Akademický článek
Morin hydrate downregulates inflammation‐mediated nitric oxide overproduction and potentiates antioxidant mechanism against anticancer drug doxorubicin oxidative hepatorenal toxicity in rats
Autor: Ademola Famurewa, Chima Ekeleme-Egedigwe, Patience Ogbu, Ayodeji Ajibare, Moshood Folawiyo, Doris Obasi, Arunaksharan Narayanankutty
Publikováno v: Avicenna Journal of Phytomedicine, Vol 13, Iss 5, Pp 475-487 (2023)
Objective: Doxorubicin (DOX) is a frontline antineoplastic drug that kills cancer cells through genotoxic mechanism; however, it induces organ toxicities. This study assayed whether morin hydrate (MOH) could abrogate DOX hepatorenal toxicity in rats.
Externí odkaz: https://doaj.org/article/2bf26b4a167e408fbb94784aa5558116
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2
Akademický článek
Nephroprotective effects of Datura stramonium leaves against methotrexate nephrotoxicity via attenuation of oxidative stress-mediated inflammation and apoptosis in rats
Autor: Esther Alum, Ademola Famurewa, Obasi Orji, Patrick M Aja, Felix Nwite, Simon Ohuche, Stanley Ukasoanya, Lucy Nnaji, Deborah Joshua, Kingsley Igwe, Stephen Chima
Publikováno v: Avicenna Journal of Phytomedicine, Vol 13, Iss 4, Pp 377-387 (2023)
Objective: Methotrexate (MTX) is a frontline antimetabolite anticancer drug which is used in different cancer treatments but its nephrotoxicity is a notable drawback that limits its clinical use. The present study was undertaken to examine whether Da
Externí odkaz: https://doaj.org/article/c315d9e3ef4b4de48290bd9aace955e0
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3
Akademický článek
Buchholzia coriacea seed extract attenuates mercury-induced cerebral and cerebellar oxidative neurotoxicity via NO signaling and suppression of oxidative stress, adenosine deaminase and acetylcholinesterase activities in rats
Autor: Simeon Egba, Ademola Famurewa, Lilian Omoruyi
Publikováno v: Avicenna Journal of Phytomedicine, Vol 12, Iss 1, Pp 42-53 (2022)
Objective: Mercury (Hg) is a classic cumulative neurotoxicant implicated in neuronal deficit via oxidative damage and inflammatory responses. We sought to investigate whether Buccholzia coriacea seed methanol extract (BCSE) would modulate oxidative n
Externí odkaz: https://doaj.org/article/b46d53ebe28846f690968ec6be3dbd7a
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4
Akademický článek
Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats
Autor: Ademola Famurewa, Gabriel Akunna, Joseph Nwafor, Onyebuchi Chukwu, Chima Ekeleme-Egedigwe, Janet Oluniran
Publikováno v: Avicenna Journal of Phytomedicine, Vol 10, Iss 3, Pp 316-324 (2020)
Objective: Diclofenac is a non-steroidal anti-inflammatory drug linked with considerable organ toxicity caused via increased generation of reactive oxygen species. We evaluated whether the antioxidant effect of virgin coconut oil (VCO) could prevent
Externí odkaz: https://doaj.org/article/c74162dfab064a06b8f327986143ac57
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5
Akademický článek
Tiliacora triandra attenuates cisplatin triggered hepatorenal and testicular toxicity in rats by modulating oxidative inflammation, apoptosis and endocrine deficit
Autor: Xiaomin Zhang, Xiaozhuang Peng, Chen Wang, Opeyemi Joshua Olatunji, Ademola Famurewa
Publikováno v: Frontiers in Bioscience-Landmark, Vol 27, Iss 2, p 044 (2022)
Purpose: Cisplatin (CIS) is a platinum based anticancer drug that has demonstrated significant efficacy against various types of cancers. Unfortunately, this drug is also famous for its severe side effects on delicate organs. Herein this study examin
Externí odkaz: https://doaj.org/article/39ad56b291e945758f1f3ad47ce209c9
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8
Assessment of Nephrotoxicity and Histopathological Lesions of Albino Rats Exposure to DD-Force and Baygon Insecticides
Autor: Oluchi Uraku, Victor U. Nwankwo, Ademola Famurewa, Anayo. Uraku
Publikováno v: International Journal of Medical and Surgical Sciences, Vol 4, Iss 4, Pp 1251-1258 (2017)
Although studies suggest adverse effects of pesticides, human exposure to insecticides in homes is increasing and reports on their health effects are limited. The study investigated nephrotoxic effects of organo phosphate and carbamate insecticides,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16533d834e23e0a2c4e2dc842cce2598
https://doi.org/10.32457/ijmss.2017.031
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9
Non Selective Inhibition of COX Activity Reversed Inflammation and Reactive Oxygen Radicals Mediated Prostate Cancer Risk and Decreased Disease Progression in Preclinical Model
Autor: Alberta Egwu Okorocha, Grace Maxwell Omabe, Maxwell Omabe, Kenneth Nwobini Omabe, Clement Ademola Famurewa
Publikováno v: Journal of Cancer Therapy. :41-49
Prostate cancer (PCa) represents the most frequent urologic diagnosis in elderly males. We have previously shown that exposure of prostate to lipopolysaccharide (LPS) promotes cancer risk. We investigated the effect of non-selective cyclooxygenase (C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::26da766ccebd28b0deca19bf6fbe9f7a
https://doi.org/10.4236/jct.2016.71005
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