Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Adem Y, Dawed"'
Autor:
Robert J. Massey, Yu Chen, Marina Panova-Noeva, Michaela Mattheus, Moneeza K. Siddiqui, Nanette C. Schloot, Antonio Ceriello, Ewan R. Pearson, Adem Y. Dawed
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background BMI variability has been associated with increased cardiovascular disease risk in individuals with type 2 diabetes, however comparison between clinical studies and real-world observational evidence has been lacking. Furthermore, i
Externí odkaz:
https://doaj.org/article/71303896acb74adc8c8ff264c1825260
Autor:
Katherine G. Young, Eram Haider McInnes, Robert J. Massey, Anna R. Kahkoska, Scott J. Pilla, Sridharan Raghavan, Maggie A. Stanislawski, Deirdre K. Tobias, Andrew P. McGovern, Adem Y. Dawed, Angus G. Jones, Ewan R. Pearson, John M. Dennis, ADA/EASD PDMI
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-20 (2023)
Abstract Background A precision medicine approach in type 2 diabetes requires the identification of clinical and biological features that are reproducibly associated with differences in clinical outcomes with specific anti-hyperglycaemic therapies. R
Externí odkaz:
https://doaj.org/article/992adc09888640ada251a7a6fb48b3d5
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract The association between body weight variability and the risk of cardiovascular disease (CVD) has been investigated previously with mixed findings. However, there has been no extensive study which systematically evaluates the current evidence
Externí odkaz:
https://doaj.org/article/e6431181773e436fb8014585b2546072
Autor:
Alaa’ Lutfi Melhem, Mehul Kumar Chourasia, Margherita Bigossi, Cyrielle Maroteau, Alasdair Taylor, Roberto Pola, Adem Y. Dawed, Aleksi Tornio, Colin N. A. Palmer, Moneeza K. Siddiqui
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: Statin intolerance impacts approximately 10% of statin users, with side effects ranging from mild myalgia to extreme intolerance resulting in myopathy and rhabdomyolysis. Statin intolerance results in poor adherence to therapy and can imp
Externí odkaz:
https://doaj.org/article/f0c988eea8714b68a7873ee741d7d42f
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: Adverse drug reactions (ADR) are a major clinical problem accounting for significant hospital admission rates, morbidity, mortality, and health care costs. One-third of people with diabetes experience at least one ADR. However, there is n
Externí odkaz:
https://doaj.org/article/f7e3cf1aa4374869abe55ffeb6f64194
Autor:
Enrique Soto-Pedre, Moneeza K. Siddiqui, Cyrielle Maroteau, Adem Y. Dawed, Alex S. Doney, Colin N. A. Palmer, Ewan R. Pearson, Graham P. Leese
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
AimsAtrial fibrillation (AF) is a risk for patients receiving thyroid hormone replacement therapy. No published work has focused on pharmacogenetics relevant to thyroid dysfunction and AF risk. We aimed to assess the effect of L-thyroxine on AF risk
Externí odkaz:
https://doaj.org/article/5c6ce436a3ce49038c91e9faed6d699c
Autor:
Naeimeh Atabaki-Pasdar, Mattias Ohlsson, Ana Viñuela, Francesca Frau, Hugo Pomares-Millan, Mark Haid, Angus G Jones, E Louise Thomas, Robert W Koivula, Azra Kurbasic, Pascal M Mutie, Hugo Fitipaldi, Juan Fernandez, Adem Y Dawed, Giuseppe N Giordano, Ian M Forgie, Timothy J McDonald, Femke Rutters, Henna Cederberg, Elizaveta Chabanova, Matilda Dale, Federico De Masi, Cecilia Engel Thomas, Kristine H Allin, Tue H Hansen, Alison Heggie, Mun-Gwan Hong, Petra J M Elders, Gwen Kennedy, Tarja Kokkola, Helle Krogh Pedersen, Anubha Mahajan, Donna McEvoy, Francois Pattou, Violeta Raverdy, Ragna S Häussler, Sapna Sharma, Henrik S Thomsen, Jagadish Vangipurapu, Henrik Vestergaard, Leen M 't Hart, Jerzy Adamski, Petra B Musholt, Soren Brage, Søren Brunak, Emmanouil Dermitzakis, Gary Frost, Torben Hansen, Markku Laakso, Oluf Pedersen, Martin Ridderstråle, Hartmut Ruetten, Andrew T Hattersley, Mark Walker, Joline W J Beulens, Andrea Mari, Jochen M Schwenk, Ramneek Gupta, Mark I McCarthy, Ewan R Pearson, Jimmy D Bell, Imre Pavo, Paul W Franks
Publikováno v:
PLoS Medicine, Vol 17, Iss 6, p e1003149 (2020)
BackgroundNon-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes serious health complications in individuals with and without type 2 diabetes (T2D). Early diagnosis of NAFLD is important, as this can help prevent irreversible damage
Externí odkaz:
https://doaj.org/article/a99f2812d7bb4af9aa894b7e0bf320bd
Autor:
Anand Thakarakkattil Narayanan Nair, Louise A. Donnelly, Adem Y. Dawed, Sushrima Gan, Ranjit M. Anjana, Mohan Viswanathan, Colin N. A. Palmer, Ewan R. Pearson
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 3, Iss 2, Pp n/a-n/a (2020)
Abstract Aim To conduct a comprehensive review of studies of glycaemic deterioration in type 2 diabetes and identify the major factors influencing progression. Methods We conducted a systematic literature search with terms linked to type 2 diabetes p
Externí odkaz:
https://doaj.org/article/1d76df3a52da4effb5ed0ebe4533cb0b
Autor:
Margherita Bigossi, Cyrielle Maroteau, Adem Y Dawed, Alasdair Taylor, Sundararajan Srinivasan, Alaa’ Lufti Melhem, Ewan R Pearson, Roberto Pola, Colin N A Palmer, Moneeza K Siddiqui
Publikováno v:
European Heart Journal - Cardiovascular Pharmacotherapy.
Background and Aims The efficacy of statin therapy is hindered by intolerance to the therapy, leading to discontinuation. Variants in SLCO1B1, which encodes the hepatic transporter OATB1B1, influence statin pharmacokinetics, resulting in altered plas
Autor:
Anand Thakarakkattil Narayanan Nair, Agata Wesolowska-Andersen, Caroline Brorsson, Aravind Lathika Rajendrakumar, Simona Hapca, Sushrima Gan, Adem Y. Dawed, Louise A. Donnelly, Rory McCrimmon, Alex S. F. Doney, Colin N. A. Palmer, Viswanathan Mohan, Ranjit M. Anjana, Andrew T. Hattersley, John M. Dennis, Ewan R. Pearson
Publikováno v:
Nature Medicine. 28:982-988