Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Adem Saglam"'
Autor:
Caterina Carraro, Lorenzo Bonaguro, Rachana Srinivasa, Martina van Uelft, Victoria Isakzai, Jonas Schulte-Schrepping, Prerna Gambhir, Tarek Elmzzahi, Jessica V. Montgomery, Hannah Hayer, Yuanfang Li, Heidi Theis, Michael Kraut, Krishnaa T. Mahbubani, Anna C. Aschenbrenner, Ireen König, Eugenio Fava, Hans-Ulrich Fried, Elena De Domenico, Marc Beyer, Adem Saglam, Joachim L. Schultze
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 10, Pp 100598- (2023)
Summary: Spatially resolved omics technologies reveal context-dependent cellular regulatory networks in tissues of interest. Beyond transcriptome analysis, information on epigenetic traits and chromatin accessibility can provide further insights on g
Externí odkaz:
https://doaj.org/article/ea2a676cee80406e904209f8d76f1bfe
Autor:
Theodore S. Kapellos, Kevin Baßler, Wataru Fujii, Christina Nalkurthi, Anna C. Schaar, Lorenzo Bonaguro, Tal Pecht, Izabela Galvao, Shobhit Agrawal, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena de Domenico, Arik Horne, Chantal Donovan, Richard Y. Kim, David Gallego-Ortega, Tessa E. Gillett, Meshal Ansari, Jonas Schulte-Schrepping, Nina Offermann, Ignazio Antignano, Burcu Sivri, Wenying Lu, Mathew S. Eapen, Martina van Uelft, Collins Osei-Sarpong, Maarten van den Berge, Hylke C. Donker, Harry J.M. Groen, Sukhwinder S. Sohal, Johanna Klein, Tina Schreiber, Andreas Feißt, Ali Önder Yildirim, Herbert B. Schiller, Martijn C. Nawijn, Matthias Becker, Kristian Händler, Marc Beyer, Melania Capasso, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Fabian J. Theis, Philip M. Hansbro, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112525- (2023)
Summary: Systemic inflammation is established as part of late-stage severe lung disease, but molecular, functional, and phenotypic changes in peripheral immune cells in early disease stages remain ill defined. Chronic obstructive pulmonary disease (C
Externí odkaz:
https://doaj.org/article/de07677bc6c241f3a6d5cd66f2c12fd0
Autor:
Jan Langkabel, Arik Horne, Lorenzo Bonaguro, Lisa Holsten, Tatiana Hesse, Alexej Knaus, Yannick Riedel, Matthias Becker, Kristian Händler, Tarek Elmzzahi, Kevin Bassler, Nico Reusch, Leon Harootoonovtch Yeghiazarian, Tal Pecht, Adem Saglam, Thomas Ulas, Anna C. Aschenbrenner, Franziska Kaiser, Caroline Kubaczka, Joachim L. Schultze, Hubert Schorle
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Synthetic embryo models have arisen as an approach to probe early development in vitro, facilitating the study of difficult to access stages. Here the authors present a simple system for generating embryo-like structures that resemble peri-implantati
Externí odkaz:
https://doaj.org/article/4777dcfcfbcb4d98ae83f5dc3f98bef3
Autor:
Lorenzo Bonaguro, Jonas Schulte-Schrepping, Caterina Carraro, Laura L. Sun, Benedikt Reiz, Ioanna Gemünd, Adem Saglam, Souad Rahmouni, Michel Georges, Peer Arts, Alexander Hoischen, Leo A.B. Joosten, Frank L. van de Veerdonk, Mihai G. Netea, Kristian Händler, Sach Mukherjee, Thomas Ulas, Joachim L. Schultze, Anna C. Aschenbrenner
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105328- (2022)
Summary: Population-scale datasets of healthy individuals capture genetic and environmental factors influencing gene expression. The expression variance of a gene of interest (GOI) can be exploited to set up a quasi loss- or gain-of-function “in po
Externí odkaz:
https://doaj.org/article/f63ab94e037a4e8987dff51c2748560c
Autor:
Theodore S. Kapellos, Lorenzo Bonaguro, Ioanna Gemünd, Nico Reusch, Adem Saglam, Emily R. Hinkley, Joachim L. Schultze
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Human monocytes are divided in three major populations; classical (CD14+CD16−), non-classical (CD14dimCD16+), and intermediate (CD14+CD16+). Each of these subsets is distinguished from each other by the expression of distinct surface markers and by
Externí odkaz:
https://doaj.org/article/8a1794b9fa2641bfb7ffaeb1a32c65bc
Autor:
CATERINA CARRARO, Lorenzo Bonaguro, Rachana Srinivasa, Martina van Uelft, Victoria Isakzai, Jonas Schulte-Schrepping, Prerna Gambhir, Heidi Theis, Michael Kraut, Krishnaa T. Mahbubani, Anna C. Aschenbrenner, Ireen König, Eugenio Fava, Hans-Ulrich Fried, Elena De Domenico, Marc D. Beyer, Adem Saglam, Joachim L. Schultze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c75092a529084a86e25249364de28dd
https://doi.org/10.2139/ssrn.4405264
https://doi.org/10.2139/ssrn.4405264
Autor:
Theodore Kapellos, Kevin Bassler, Wataru Fujii, Tal Pecht, Lorenzo Bonaguro, Izabela Galvao, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena De Domenico, Arik Horne, Chantal Donovan, Richard Y. Kim, David Gallego-Ortega, Matthias Becker, Kristian Händler, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Phil M. Hansbro, Dirk Skowasch, Joachim L. Schultze
Publikováno v:
03.02 - Airway cell biology and immunopathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748bd6c2e268e4b3f3e9dd6bf2f0d7ec
https://doi.org/10.1183/13993003.congress-2022.lsc-0210
https://doi.org/10.1183/13993003.congress-2022.lsc-0210
Autor:
Malte D. Luecken, Laure-Emmanuelle Zaragosi, Elo Madissoon, Lisa Sikkema, Alexandra B. Firsova, Elena De Domenico, Louis Kümmerle, Adem Saglam, Marijn Berg, Aurore C.A. Gay, Janine Schniering, Christoph H. Mayr, Xesús M. Abalo, Ludvig Larsson, Alexandros Sountoulidis, Sarah A. Teichmann, Karen van Eunen, Gerard H. Koppelman, Kourosh Saeb-Parsy, Sylvie Leroy, Pippa Powell, Ugis Sarkans, Wim Timens, Joakim Lundeberg, Maarten van den Berge, Mats Nilsson, Peter Horváth, Jessica Denning, Irene Papatheodorou, Joachim L. Schultze, Herbert B. Schiller, Pascal Barbry, Ilya Petoukhov, Alexander V. Misharin, Ian M. Adcock, Michael von Papen, Fabian J. Theis, Christos Samakovlis, Kerstin B. Meyer, Martijn C. Nawijn
Publikováno v:
European Respiratory Journal
The European respiratory journal 60(2), 2102057 (2022). doi:10.1183/13993003.02057-2021
Eur. Respir. J. 59:2102057 (2022)
The European respiratory journal 60(2), 2102057 (2022). doi:10.1183/13993003.02057-2021
Eur. Respir. J. 59:2102057 (2022)
The Human Cell Atlas (HCA) consortium aims to establish an atlas of all organs in the healthy human body at single-cell resolution to increase our understanding of basic biological processes that govern development, physiology and anatomy, and to acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f581433ea51435d26d857eb0a83d27a3
https://hdl.handle.net/11370/eeca5057-97a6-45f7-9dac-92e84b6d1f46
https://hdl.handle.net/11370/eeca5057-97a6-45f7-9dac-92e84b6d1f46
Autor:
Daniel Wendisch, Christof von Kalle, Theodore S. Kapellos, Henrik E. Mei, Kristian Händler, Katrin-Moira Heim, Kevin Baßler, Alexander Uhrig, Charlotte Thibeault, Miriam Stegemann, Christoph R. Glösenkamp, Antoine-Emmanuel Saliba, Lorenzo Bonaguro, Stephan Schlickeiser, Hans-Dieter Volk, Matthias Becker, Yang Li, Andreas C. Hocke, Elena De Domenico, Moritz Pfeiffer, Michael To Vinh, Michael Beckstette, Miriam Herbert, Sophia Brumhard, Martin Grasshoff, Kim Melanie Kaiser, Tobias Krammer, Arik Horne, Anna Drews, Norbert Suttorp, Birgit Sawitzki, Deutsche Covid Omics Initiative, Martin Witzenrath, Robert Geffers, Tal Pecht, Florian Kurth, Jacob Nattermann, Adem Saglam, Joachim L. Schultze, Jan Raabe, Bowen Zhang, Daniela Paclik, Linda Jürgens, Désirée Kunkel, Benjamin Krämer, Leif E. Sander, Jonas Schulte-Schrepping, Felix Machleidt, Cheng-Jian Xu, Christian Meisel, Claudia Conrad, Anna C. Aschenbrenner, Thomas Ulas, Stefan Hippenstiel, Oliver Dietrich, Gereon Rieke, Holger Müller-Redetzky, Axel Schulz, Christian Drosten, Nico Reusch, Christine Goffinet, Laure Bousquillon de Jarcy, Ehsan Vafadarnejad
‘Severe Acute Respiratory Syndrome - Coronavirus-2’ (SARS-CoV-2) infection causes Coronavirus Disease 2019 (COVID-19), a mild to moderate respiratory tract infection in the majority of patients. A subset of patients, however, progresses to severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ed6fbdaf8222e424f85575517bb89a
Autor:
Esteban Ballestar, Jaydeep Bhat, Sajad Ahmad Bhat, Ziyi Chen, Shubhada Chiplunkar, Anjali deSouza, Avery DeVries, Humberto J. Ferreira, Sanjeev Galande, Ashok Giri, Anita Q. Gomes, Mariam Hakobyan, Mark Hartmann, Emily Hinkley, Dieter Kabelitz, Hemlata Kotkar, Jens Langstein, Jasmine Li, Tianlu Li, Wenhui Li, Daniel B. Lipka, Magdalena A. Machnicka, Ayush Madhok, Chinna Susan Philip, Rosario Michael Piro, Katarzyna Placek, F. Xiao-Feng Qin, Javier Rodríguez-Ubreva, Brendan E. Russ, Adem Saglam, Nina Schmolka, Maximilian Schönung, Jonas Schulte-Schrepping, Joachim L. Schultze, Bruno Silva-Santos, Sina Stäble, Shalini Kashipathi Sureshbabu, Aurore Touzart, Stephen J. Turner, Donata Vercelli, Justyna A. Wierzbinska, Bartek Wilczynski, Aiping Wu, Lianjun Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d63a38966a9dedc2263bdefad36c5a
https://doi.org/10.1016/b978-0-12-817964-2.09991-3
https://doi.org/10.1016/b978-0-12-817964-2.09991-3