Gene expression in chronic granulomatous disease and interferon‐γ receptor‐deficient cells treated in vitro with interferon‐γ

Autor: Peter E. Newburger, Irene Keller, Michal J. Okoniewski, Zhiqing Zhu, Adem Bilican, Cedric Simillion, Daniel Wüthrich, Martino Colombo, Antonio Condino-Neto, Rémy Bruggmann, Josias Brito Frazão

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Interferon-γ (IFN-γ) plays an important role in innate and adaptive immunity against intracellular infections and is used clinically for the prevention and control of infections in chronic granulomatous disease (CGD) and inborn defects in the IFN-�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b2ece5394d41566fa0b40d3131d883

Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in

Autor: Yves F, Widmer, Adem, Bilican, Rémy, Bruggmann, Simon G, Sprecher

Publikováno v: Genetics

Memory formation is achieved by genetically tightly controlled molecular pathways that result in a change of synaptic strength and synapse organization. While for short-term memory traces, rapidly acting biochemical pathways are in place, the formati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fb338ee264e434c98c5a2e2079fd3b2
https://pubmed.ncbi.nlm.nih.gov/29925565

Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility

Autor: Yannick Romero, Henrik Kaessmann, Maria Warnefors, Christelle Borel, Adem Bilican, Lee B. Smith, Céline Zimmermann, Serge Nef, Noora Kotaja

Publikováno v: PLoS ONE
PLOS ONE, Vol. 9, No 9 (2014) P. e107023
Zimmermann, C, Romero, Y, Warnefors, M, Bilican, A, Borel, C, Smith, L B, Kotaja, N, Kaessmann, H & Nef, S 2014, ' Germ Cell-Specific Targeting of DICER or DGCR8 Reveals a Novel Role for Endo-siRNAs in the Progression of Mammalian Spermatogenesis and Male Fertility ', PLoS ONE, vol. 9, no. 9, e107023, pp. e107023 . https://doi.org/10.1371/journal.pone.0107023
PLoS ONE, Vol 9, Iss 9, p e107023 (2014)
PLoS One, vol. 9, no. 9, pp. e107023

Small non-coding RNAs act as critical regulators of gene expression and are essential for male germ cell development and spermatogenesis. Previously, we showed that germ cell-specific inactivation of Dicer1, an endonuclease essential for the biogenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf63595320f5e9870ec27857ad48e96
https://pubmed.ncbi.nlm.nih.gov/25244517