Výsledky vyhledávání - "Adelyn Bolithon"

CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma

Autor: Eun-Young, Kang, Ashley, Weir, Nicola S, Meagher, Kyo, Farrington, Gregg S, Nelson, Prafull, Ghatage, Cheng-Han, Lee, Marjorie J, Riggan, Adelyn, Bolithon, Gordana, Popovic, Betty, Leung, Katrina, Tang, Neil, Lambie, Joshua, Millstein, Jennifer, Alsop, Michael S, Anglesio, Beyhan, Ataseven, Ellen, Barlow, Matthias W, Beckmann, Jessica, Berger, Christiani, Bisinotto, Hans, Bösmüller, Jessica, Boros, Alison H, Brand, Angela, Brooks-Wilson, Sara Y, Brucker, Michael E, Carney, Yovanni, Casablanca, Alicia, Cazorla-Jiménez, Paul A, Cohen, Thomas P, Conrads, Linda S, Cook, Penny, Coulson, Madeleine, Courtney-Brooks, Daniel W, Cramer, Philip, Crowe, Julie M, Cunningham, Cezary, Cybulski, Kathleen M, Darcy, Mona A, El-Bahrawy, Esther, Elishaev, Ramona, Erber, Rhonda, Farrell, Sian, Fereday, Anna, Fischer, María J, García, Simon A, Gayther, Aleksandra, Gentry-Maharaj, C Blake, Gilks, Marcel, Grube, Paul R, Harnett, Shariska Petersen, Harrington, Philipp, Harter, Arndt, Hartmann, Jonathan L, Hecht, Sebastian, Heikaus, Alexander, Hein, Florian, Heitz, Joy, Hendley, Brenda Y, Hernandez, Susanna Hernando, Polo, Sabine, Heublein, Akira, Hirasawa, Estrid, Høgdall, Claus K, Høgdall, Hugo M, Horlings, David G, Huntsman, Tomasz, Huzarski, Andrea, Jewell, Mercedes, Jimenez-Linan, Michael E, Jones, Scott H, Kaufmann, Catherine J, Kennedy, Dineo, Khabele, Felix K F, Kommoss, Roy F P M, Kruitwagen, Diether, Lambrechts, Nhu D, Le, Marcin, Lener, Jenny, Lester, Yee, Leung, Anna, Linder, Liselore, Loverix, Jan, Lubiński, Rashna, Madan, G Larry, Maxwell, Francesmary, Modugno, Susan L, Neuhausen, Alexander, Olawaiye, Siel, Olbrecht, Sandra, Orsulic, José, Palacios, Celeste Leigh, Pearce, Malcolm C, Pike, Carmel M, Quinn, Ganendra Raj, Mohan, Cristina, Rodríguez-Antona, Matthias, Ruebner, Andy, Ryan, Stuart G, Salfinger, Naoko, Sasamoto, Joellen M, Schildkraut, Minouk J, Schoemaker, Mitul, Shah, Raghwa, Sharma, Yurii B, Shvetsov, Naveena, Singh, Gabe S, Sonke, Linda, Steele, Colin J R, Stewart, Karin, Sundfeldt, Anthony J, Swerdlow, Aline, Talhouk, Adeline, Tan, Sarah E, Taylor, Kathryn L, Terry, Aleksandra, Tołoczko, Nadia, Traficante, Koen K, Van de Vijver, Maaike A, van der Aa, Toon, Van Gorp, Els, Van Nieuwenhuysen, Lilian, van-Wagensveld, Ignace, Vergote, Robert A, Vierkant, Chen, Wang, Lynne R, Wilkens, Stacey J, Winham, Anna H, Wu, Javier, Benitez, Andrew, Berchuck, Francisco J, Candido Dos Reis, Anna, DeFazio, Peter A, Fasching, Ellen L, Goode, Marc T, Goodman, Jacek, Gronwald, Beth Y, Karlan, Stefan, Kommoss, Usha, Menon, Hans-Peter, Sinn, Annette, Staebler, James D, Brenton, David D, Bowtell, Paul D P, Pharoah, Susan J, Ramus, Martin, Köbel

Publikováno v: Cancer, 129(5), 697-713. Wiley
Cancer: interdisciplinary international journal of the American Cancer Society

BACKGROUND: Cyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo-ovarian high-grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification and CCNE1 overexpression with sur

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https://cris.maastrichtuniversity.nl/en/publications/c478396c-2f30-41bf-8d8e-e8eb052ddffb

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Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes

Autor: Nicola S, Meagher, Kylie L, Gorringe, Matthew, Wakefield, Adelyn, Bolithon, Chi Nam Ignatius, Pang, Derek S, Chiu, Michael S, Anglesio, Kylie-Ann, Mallitt, Jennifer A, Doherty, Holly R, Harris, Joellen M, Schildkraut, Andrew, Berchuck, Kara L, Cushing-Haugen, Ksenia, Chezar, Angela, Chou, Adeline, Tan, Jennifer, Alsop, Ellen, Barlow, Matthias W, Beckmann, Jessica, Boros, David D L, Bowtell, Alison H, Brand, James D, Brenton, Ian, Campbell, Dane, Cheasley, Joshua, Cohen, Cezary, Cybulski, Esther, Elishaev, Ramona, Erber, Rhonda, Farrell, Anna, Fischer, Zhuxuan, Fu, Blake, Gilks, Anthony J, Gill, Charlie, Gourley, Marcel, Grube, Paul R, Harnett, Arndt, Hartmann, Anusha, Hettiaratchi, Claus K, Høgdall, Tomasz, Huzarski, Anna, Jakubowska, Mercedes, Jimenez-Linan, Catherine J, Kennedy, Byoung-Gie, Kim, Jae-Weon, Kim, Jae-Hoon, Kim, Kayla, Klett, Jennifer M, Koziak, Tiffany, Lai, Angela, Laslavic, Jenny, Lester, Yee, Leung, Na, Li, Winston, Liauw, Belle W X, Lim, Anna, Linder, Jan, Lubiński, Sakshi, Mahale, Constantina, Mateoiu, Simone, McInerny, Janusz, Menkiszak, Parham, Minoo, Suzana, Mittelstadt, David, Morris, Sandra, Orsulic, Sang-Yoon, Park, Celeste Leigh, Pearce, John V, Pearson, Malcolm C, Pike, Carmel M, Quinn, Ganendra Raj, Mohan, Jianyu, Rao, Marjorie J, Riggan, Matthias, Ruebner, Stuart, Salfinger, Clare L, Scott, Mitul, Shah, Helen, Steed, Colin J R, Stewart, Deepak, Subramanian, Soseul, Sung, Katrina, Tang, Paul, Timpson, Robyn L, Ward, Rebekka, Wiedenhoefer, Heather, Thorne, Paul A, Cohen, Philip, Crowe, Peter A, Fasching, Jacek, Gronwald, Nicholas J, Hawkins, Estrid, Høgdall, David G, Huntsman, Paul A, James, Beth Y, Karlan, Linda E, Kelemen, Stefan, Kommoss, Gottfried E, Konecny, Francesmary, Modugno, Sue K, Park, Annette, Staebler, Karin, Sundfeldt, Anna H, Wu, Aline, Talhouk, Paul D P, Pharoah, Lyndal, Anderson, Anna, DeFazio, Martin, Köbel, Michael L, Friedlander, Susan J, Ramus

Publikováno v: Meagher, N S, Gorringe, K L, Wakefield, M J, Bolithon, A, Pang, C N I, Chiu, D S, Anglesio, M S, Mallitt, K, Doherty, J A, Harris, H R, Schildkraut, J M, Berchuck, A, Cushing-haugen, K L, Chezar, K, Chou, A, Tan, A, Alsop, J, Barlow, E, Beckmann, M W, Boros, J, Bowtell, D D, Brand, A H, Brenton, J D, Campbell, I, Cheasley, D, Cohen, J, Cybulski, C, Elishaev, E, Erber, R, Farrell, R, Fischer, A, Fu, Z, Gilks, B, Gill, A J, Gourley, C, Grube, M, Harnett, P, Hartmann, A, Hettiaratchi, A, Høgdall, C K, Huzarski, T, Jakubowska, A, Jimenez-linan, M, Kennedy, C J, Kim, B, Kim, J, Kim, J, Klett, K, Koziak, J, Lai, T, Laslavic, A, Lester, J, Leung, Y, Li, N, Liauw, W, Lim, B W X, Linder, A, Lubinski, J, Mahale, S, Mateoiu, C, Mcinerny, S, Menkiszak, J, Minoo, P, Mittelstadt, S, Morris, D, Orsulic, S, Park, S Y, Pearce, C L, Pearson, J V, Pike, M C, Quinn, C M, Mohan, G R, Rao, J, Riggan, M J, Ruebner, M, Salfinger, S, Scott, C L, Shah, M, Steed, H, Stewart, C J R, Subramanian, D, Sung, S, Tang, K, Timpson, P, Ward, R L, Wiedenhoefer, R, Thorne, H, Cohen, P A, Crowe, P, Fasching, P A, Gronwald, J, Hawkins, N J, Høgdall, E, Huntsman, D G, James, P A, Karlan, B Y, Kelemen, L E, Kommoss, S, Konecny, G E, Modugno, F, Park, S K, Staebler, A, Sundfeldt, K, Wu, A H, Talhouk, A, Pharoah, P D P, Anderson, L, Defazio, A, Köbel, M, Friedlander, M L & Ramus, S J 2022, ' Gene expression profiling of mucinous ovarian tumors and comparison with upper and lower gastrointestinal tumors identifies markers associated with adverse outcomes. ', Clinical Cancer Research . https://doi.org/10.1158/1078-0432.CCR-22-1206, https://doi.org/10.1158/1078-0432.CCR-22-1206
AOCS Grp, Australian Pancreatic Genome Initi & kConFab Investigators 2022, ' Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes ', Clinical Cancer Research, vol. 28, no. 24, pp. 5383-5395 . https://doi.org/10.1158/1078-0432.CCR-22-1206

Purpose: Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis and lacks biomarkers to aid stage I adjuvant treatment. Differentiating primary MOC from gastrointestinal (GI) metastases to the ovary is also chall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e7e60454f3d65c0cafb4f51f254763
https://doi.org/10.1158/1078-0432.ccr-22-1206

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Supplementary Methods 1 from Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes

Autor: Susan J. Ramus, Michael L. Friedlander, Martin Köbel, Anna DeFazio, Lyndal Anderson, Paul D.P. Pharoah, Aline Talhouk, Anna H. Wu, Karin Sundfeldt, Annette Staebler, Sue K. Park, Francesmary Modugno, Gottfried E. Konecny, Stefan Kommoss, Linda E. Kelemen, Beth Y. Karlan, Paul A. James, David G. Huntsman, Estrid Høgdall, Nicholas J. Hawkins, Jacek Gronwald, Peter A. Fasching, Philip Crowe, Paul A. Cohen, Heather Thorne, Rebekka Wiedenhoefer, Robyn L. Ward, Paul Timpson, Katrina Tang, Soseul Sung, Deepak Subramanian, Colin J.R. Stewart, Helen Steed, Mitul Shah, Clare L. Scott, Stuart Salfinger, Matthias Ruebner, Marjorie J. Riggan, Jianyu Rao, Ganendra Raj Mohan, Carmel M. Quinn, Malcolm C. Pike, John V. Pearson, Celeste Leigh Pearce, Sang-Yoon Park, Sandra Orsulic, David Morris, Suzana Mittelstadt, Parham Minoo, Janusz Menkiszak, Simone McInerny, Constantina Mateoiu, Sakshi Mahale, Jan Lubiński, Anna Linder, Belle W.X. Lim, Winston Liauw, Na Li, Yee Leung, Jenny Lester, Angela Laslavic, Tiffany Lai, Jennifer M. Koziak, Kayla Klett, Jae-Hoon Kim, Jae-Weon Kim, Byoung-Gie Kim, Catherine J. Kennedy, Mercedes Jimenez-Linan, Anna Jakubowska, Tomasz Huzarski, Claus K. Høgdall, Anusha Hettiaratchi, Arndt Hartmann, Paul R. Harnett, Marcel Grube, Charlie Gourley, Anthony J. Gill, Blake Gilks, Zhuxuan Fu, Anna Fischer, Rhonda Farrell, Ramona Erber, Esther Elishaev, Cezary Cybulski, Joshua Cohen, Dane Cheasley, Ian Campbell, James D. Brenton, Alison H. Brand, David D.L. Bowtell, Jessica Boros, Matthias W. Beckmann, Ellen Barlow, Jennifer Alsop, Adeline Tan, Angela Chou, Ksenia Chezar, Kara L. Cushing-Haugen, Andrew Berchuck, Joellen M. Schildkraut, Holly R. Harris, Jennifer A. Doherty, Kylie-Ann Mallitt, Michael S. Anglesio, Derek S. Chiu, Chi Nam Ignatius Pang, Adelyn Bolithon, Matthew Wakefield, Kylie L. Gorringe, Nicola S. Meagher

Supplementary Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d64fdeb076edf5e13130f883c3b232f
https://doi.org/10.1158/1078-0432.22488651

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Supplementary Figures S1-S13 from Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes

Supplementary Figures S1-S13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b82af9a17b85552015e3924057576f0
https://doi.org/10.1158/1078-0432.22488654

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Data from Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes

Purpose:Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis and lacks biomarkers to aid stage I adjuvant treatment. Differentiating primary MOC from gastrointestinal (GI) metastases to the ovary is also challe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcad0fe969c428ac7e34a902af89649
https://doi.org/10.1158/1078-0432.c.6532782

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Supplementary Tables S1-S11 from Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes

Supplementary Tables S1-S11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7716591465bc87d4a9d862bf4b44e943
https://doi.org/10.1158/1078-0432.22488645.v1

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MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma

Autor: Thomas P. Conrads, Gordana C. Popovic, Lilian van-Wagensveld, Ignace Vergote, Ellen L. Barlow, Annalyn Da-Anoy, Stacey J. Winham, Nicola S. Meagher, Catherine J. Kennedy, Michael Jones, Sabine Heublein, Linda E. Kelemen, Neil Lambie, Paul D.P. Pharoah, Peter Sinn, Claus Høgdall, Sanela Bilic, Alexander Hein, Yovanni Casablanca, Aline Talhouk, Christiani Bisinotto, Chiu-Chen Tseng, Matthias Ruebner, Nhu D Le, Estrid Høgdall, Arndt Hartmann, Malcolm C. Pike, Philipp Harter, Nina Neudeck, Sarah Taylor, Juergen Andress, Anna Fischer, Kunle Odunsi, Naoko Sasamoto, Janine M. Joseph, Marina Pavanello, Derek S. Chiu, Eun Young Kang, Ellen L. Goode, Susan L. Neuhausen, Rhonda Farrell, Stefan Kommoss, Esther Elishaev, Jenny Lester, Yu Yu, Carmel Quinn, Betty Leung, Susan J. Ramus, Jesus Garcia-Donas, Colin J.R. Stewart, Penny Coulson, Joshua Millstein, Adelyn Bolithon, Maria Lycke, Chen Wang, Andreas du Bois, Francesmary Modugno, Alexander B. Olawaiye, Celeste Leigh Pearce, Jessica Boros, G. Larry Maxwell, Constantina Mateoiu, Francisco José Candido dos Reis, Diether Lambrechts, Liselore Loverix, Katrina Tang, Siel Olbrecht, John Lewis Etter, Yee Leung, Kirsten B. Moysich, Katherine LaVigne-Mager, Matthias W. Beckmann, Kathryn L. Terry, Felix K. F. Kommoss, Arantzazu Barquin-Garcia, Monica Yagüe-Fernandez, Sergio Ruiz-Llorente, Helen Steed, M Grube, Michael S Anglesio, Nikilyn Nevins, Sebastian M. Armasu, Mona El-Bahrawy, Beyhan Ataseven, Minouk J. Schoemaker, Annette Staebler, Peter A. Fasching, Gottfried E. Konecny, Terry K. Morgan, Simon A. Gayther, Anna deFazio, Robert A. Vierkant, Martin Köbel, Ramona Erber, Cheng-Han Lee, Paul R. Harnett, Greg Robertson, Linda S Cook, Philip J. Crowe, Daniel W. Cramer, Alison Brand, Yajue Huang, Anusha Hettiaratchi, Florian Heitz, Beth Y. Karlan, Anthony J. Swerdlow, Adeline Tan, Anna H. Wu, Akira Hirasawa, Kate Lawrenson, Karin Sundfeldt, Paul A. Cohen, Robert P. Edwards, Hugo M. Horlings

Publikováno v: Virchows Arch
Kang, E Y, Millstein, J, Popovic, G, Meagher, N S, Bolithon, A, Talhouk, A, Chiu, D S, Anglesio, M S, Leung, B, Tang, K, Lambie, N, Pavanello, M, Da-anoy, A, Lambrechts, D, Loverix, L, Olbrecht, S, Bisinotto, C, Garcia-Donas, J, Ruiz-Llorente, S, Yagüe-Fernandez, M, Edwards, R P, Elishaev, E, Olawaiye, A, Taylor, S, Ataseven, B, du Bois, A, Harter, P, Lester, J, Høgdall, C K, Armasu, S M, Huang, Y, Vierkant, R A, Wang, C, Winham, S J, Heublein, S, Kommoss, F K F, Cramer, D W, Sasamoto, N, van-Wagensveld, L, Lycke, M, Mateoiu, C, Joseph, J, Pike, M C, Odunsi, K, Tseng, C C, Pearce, C L, Bilic, S, Conrads, T P, Hartmann, A, Hein, A, Jones, M E, Leung, Y, Beckmann, M W, Ruebner, M, Schoemaker, M J, Terry, K L, El-Bahrawy, M A, Coulson, P, Etter, J L, LaVigne-Mager, K, Andress, J, Grube, M, Fischer, A, Neudeck, N, Robertson, G, Farrell, R, Barlow, E, Quinn, C, Hettiaratchi, A, Casablanca, Y, Erber, R, Stewart, C J R, Tan, A, Yu, Y, Boros, J, Brand, A H, Harnett, P R, Kennedy, C J, Nevins, N, Morgan, T, Fasching, P A, Vergote, I, Swerdlow, A J, Candido dos Reis, F J, Maxwell, G L, Neuhausen, S L, Barquin-Garcia, A, Modugno, F, Moysich, K B, Crowe, P J, Hirasawa, A, Heitz, F, Karlan, B Y, Goode, E L, Sinn, P, Horlings, H M, Høgdall, E, Sundfeldt, K, Kommoss, S, Staebler, A, Wu, A H, Cohen, P A, DeFazio, A, Lee, C H, Steed, H, Le, N D, Gayther, S A, Lawrenson, K, Pharoah, P D P, Konecny, G, Cook, L S, Ramus, S J, Kelemen, L E & Köbel, M 2022, ' MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma ', Virchows Archiv, vol. 480, pp. 855–871 . https://doi.org/10.1007/s00428-021-03232-0

Tubo-ovarian high-grade serous carcinomas (HGSC) are highly proliferative neoplasms that generally respond well to platinum/taxane chemotherapy. We recently identified minichromosome maintenance complex component 3 (MCM3), which is involved in the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e268638b52d1199839f66760e65433
https://pubmed.ncbi.nlm.nih.gov/34782936

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Abstract B37: Germline mutations in new susceptibility genes for non-high-grade serous ovarian cancer

Publikováno v: Clinical Cancer Research. 26:B37-B37

Improving risk prediction and prevention strategies through identifying new susceptibility genes for non-high-grade serous ovarian cancer (non-HGS) would represent an important advance in reducing incidence and mortality. Epithelial ovarian cancer (E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c13890df6bbbb2cfb5b18e2564c0fbf
https://doi.org/10.1158/1557-3265.ovca19-b37

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Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells

Autor: Adelyn Bolithon, Craig Slattery, Philip Poronnik, Wade A. Kruger, Deanne H. Hryciw, Aven Lee, Jessica F. Briffa

Publikováno v: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 30(5)

Receptor-mediated endocytosis of albumin by the renal proximal tubule requires a number of proteins including megalin/cubilin, sodium/hydrogen exchanger isoform 3 (NHE3) and ClC-5, as well as the PSD-95/Dlg/Zo-1 (PDZ) scaffold sodium/hydrogen exchang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265ecda1ec9aa42e088f8b0ca4abfbf9
https://pubmed.ncbi.nlm.nih.gov/23075606

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