Distribution, Diversity and Roles of CRISPR-Cas Systems in Human and Animal Pathogenic Streptococci

Autor: Coralie Lemaire, Brice Le Gallou, Philippe Lanotte, Laurent Mereghetti, Adeline Pastuszka

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

Streptococci form a wide group of bacteria and are involved in both human and animal pathologies. Among pathogenic isolates, differences have been highlighted especially concerning their adaptation and virulence profiles. CRISPR-Cas systems have been

Externí odkaz: https://doaj.org/article/926de7e91d38406dbf762fe7e44eb04c

Feature of Adhesins Produced by Human Clinical Isolates of Mycobacterium intracellulare, Mycobacterium intracellulare subsp. chimaera and Closely Related Species

Autor: Louise H. Lefrancois, Thierry Cochard, Maxime Branger, Olivia Peuchant, Cyril Conde, Adeline Pastuszka, Camille Locht, Philippe Lanotte, Franck Biet

Publikováno v: Microorganisms, Vol 8, Iss 8, p 1154 (2020)

The Mycobacterium avium complex includes two closely related species, Mycobacterium avium and Mycobacterium intracellulare. They are opportunistic pathogens in humans and responsible for severe disease in a wide variety of animals. Yet, little is kno

Externí odkaz: https://doaj.org/article/44130f42ab3c44a9bc7e5568208f2c14

Multiplex PCR assay targeting Trichomonas vaginalis: need for biological evaluation and interpretation

Autor: Adélaïde, Chesnay, Adeline, Pastuszka, Lucie, Richard, Agnès, Beby-Defaux, Estelle, Cateau, Cécile, Le Brun, Guillaume, Desoubeaux, Philippe, Lanotte

Publikováno v: Diagnostic Microbiology and Infectious Disease. 104:115808

In a retrospective study, we used sequencing to investigate Trichomonas vaginalis-positive specimens (genital, rectal and pharyngeal) with the Allplex™ STI Essential or the Anyplex™-II-STI-7 assays. Our results confirm that majority of T. vaginal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8843884c04bbd1ab19f5ae70243666
https://doi.org/10.1016/j.diagmicrobio.2022.115808

Functional Study of the Type II-A CRISPR-Cas System of Streptococcus agalactiae Hypervirulent Strains

Autor: Emilie Camiade, Geneviève M. Rousseau, Adeline Pastuszka, Philippe Lanotte, Laurent Mereghetti, Clémence Beauruelle, Philippe Horvath, Sylvain Moineau

Publikováno v: The CRISPR Journal
The CRISPR Journal, 2021, 4 (2), pp.233-242. ⟨10.1089/crispr.2020.0145⟩

International audience; Nearly all strains of Streptococcus agalactiae, the leading cause of invasive infections in neonates, encode a type II-A clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system. Interestingly, S. agalacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec204731551ad47a5f81151913f7b07
https://hal.inrae.fr/hal-03205479

Seven Years Leptospirosis Follow-Up in a Critical Care Unit of a French Metropolitan Hospital; Role of Real Time PCR for a Quick and Acute Diagnosis

Autor: Stephan Ehrmann, Olivier Bahuaud, Adeline Pastuszka, Cécile Le Brun, Philippe Lanotte

Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 3011, p 3011 (2020)
Journal of Clinical Medicine
Journal of Clinical Medicine, MDPI, 2020, 9 (9), 10 p. ⟨10.3390/jcm9093011⟩
Journal of Clinical Medicine, 2020, 9 (9), 10 p. ⟨10.3390/jcm9093011⟩

International audience; (1) Background: Leptospirosis infection can lead to multiple organ failure, requiring hospitalization in an intensive care unit for supportive care, along with initiation of an adapted antibiotic therapy. Achieving a quick dia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e2db48d11e3b5f46fd7f9083cf1f35
https://www.mdpi.com/2077-0383/9/9/3011