Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Adeline Govekung"'
Autor:
Douglas E. Brough, Roshanak Tolouei Semnani, Steven Zilko, Bolinger Cheryl G, Maha Abdeladhim, Rahim Johnson, Adeline Govekung, Shamim Ahmad, Lindsey Shepard, Mengyan Du, Kannan Kunchithapautham, Jacques Plummer, Bernward Klocke, Shah Rutul R, Shourik Dutta, Carol Poortman, Byron Koenitzer, Tim Chan, Taranjit Athwal, Simon Metenou, Sean P. Scott, Carlos Sailor, Christian Zinser, Helen Sabzevari
Publikováno v:
Blood. 138:1694-1694
Traditional methods for chimeric antigen receptor (CAR) T manufacturing utilize viral vectors, ex vivo activation and expansion of T cells to achieve clinically relevant cell numbers, which leads to an exhausted T cell phenotype, high manufacturing c
Autor:
Padma Kamineny, Simon Metenou, Adeline Govekung, Marion Chakiath, Jose Velez, Shah Rutul R, Tim Chan, Jacques Plummer, Fernando Carvajal-Borda, Helen Sabzevari, Carol Poortman, Xiaohong Ma, Mary L. Disis, Lindsey Shepard
Publikováno v:
Cancer Research. 80:6593-6593
Ovarian cancer is the most lethal of gynecologic cancers. Chimeric antigen receptor (CAR)-T cells have improved clinical outcomes in hematological malignancies; however similar responses have not yet been achieved for solid tumors. Furthermore, tradi