Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Adeline Divoux"'
Autor:
Edina Erdos, Katalin Sandor, Crystal L. Young-Erdos, Laszlo Halasz, Steven R. Smith, Timothy F. Osborne, Adeline Divoux
Publikováno v:
Cells, Vol 13, Iss 1, p 86 (2023)
Determining the mechanism driving body fat distribution will provide insights into obesity-related health risks. We used functional genomics tools to profile the epigenomic landscape to help infer the differential transcriptional potential of apple-
Externí odkaz:
https://doaj.org/article/986d819370ce4fa08fd33ece892becdc
Autor:
Katie L. Whytock, Adeline Divoux, Yifei Sun, Meghan Hopf, Reichelle X. Yeo, Maria F. Pino, GongXin Yu, Steven R. Smith, Martin J. Walsh, Lauren M. Sparks
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102054- (2023)
Summary: Automated single-cell dispensing is incompatible with white adipose tissue (WAT) due to lipid-laden adipocytes. Single-nuclei RNA-Seq permits transcriptional profiling of all cells from WAT. Human WAT faces unique technical challenges in iso
Externí odkaz:
https://doaj.org/article/6f05c012201949db8ce2f85ec5f3f189
Autor:
Katie L. Whytock, Yifei Sun, Adeline Divoux, GongXin Yu, Steven R. Smith, Martin J. Walsh, Lauren M. Sparks
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104772- (2022)
Summary: White adipose tissue (WAT) is a complex mixture of adipocytes and non-adipogenic cells. Characterizing the cellular composition of WAT is critical for identifying where potential alterations occur that impact metabolism. Most single-cell (sc
Externí odkaz:
https://doaj.org/article/4ec7ebab50b342d4b9bb0123c835bb39
Autor:
Adeline Divoux, Alexey Eroshkin, Edina Erdos, Katalin Sandor, Timothy F. Osborne, Steven R. Smith
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Preferential accumulation of fat in the gluteo-femoral (GF) depot (pear shape) rather than in the abdominal (A) depot (apple shape), protects against the development of metabolic diseases but the underlying molecular mechanism is still unknown. Recen
Externí odkaz:
https://doaj.org/article/8c7ca6544fba4c3da40d4c9c2e8b2890
Publikováno v:
Cells, Vol 11, Iss 5, p 848 (2022)
Polycystic ovary syndrome (PCOS) is often associated with metabolic syndrome features, including central obesity, suggesting that adipose tissue (AT) is a key organ in PCOS pathobiology. In this study, we compared both abdominal (ABD) and gluteofemor
Externí odkaz:
https://doaj.org/article/d7d3804384e947458df283dc1d778274
Autor:
Adeline Divoux, Katalin Sandor, Dora Bojcsuk, Amlan Talukder, Xiaoman Li, Balint L. Balint, Timothy F. Osborne, Steven R. Smith
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-15 (2018)
Abstract Background Increased lower body fat is associated with reduced cardiometabolic risk. The molecular basis for depot-specific differences in gluteofemoral (GF) compared with abdominal (A) subcutaneous adipocyte function is poorly understood. I
Externí odkaz:
https://doaj.org/article/c0e5755a644146e6b3853adea4fa4ba7
Autor:
Edina Erdos, Adeline Divoux, Katalin Sandor, Laszlo Halasz, Steven R. Smith, Timothy F. Osborne
Publikováno v:
Genes & Development. 36:566-581
Accumulation of fat above the waist is an important risk factor in developing obesity-related comorbidities independently of BMI or total fat mass. Deciphering the gene regulatory programs of the adipose tissue precursor cells within upper body or ab
Publikováno v:
Formation emploi. :23-43
Les ecoles menageres agricoles proposent des enseignements techniques destines aux jeunes filles vivant a la campagne. Il s’agit de les convaincre de travailler au sein de la ferme familiale dans leur village, dans un contexte ou, sur la periode191
Autor:
Timothy F. Osborne, Joshua S Smith, Adeline Divoux, Dóra Bojcsuk, Fanchao Yi, Balint L. Balint, Katalin Sandor, Meghan E. Hopf, Steven R. Smith
Publikováno v:
Journal of the Endocrine Society
Background Preferential accumulation of fat in the upper body (apple shape) is associated with higher risk of developing metabolic syndrome relative to lower body fat (pear shape). We previously discovered that chromatin openness partially defined th
Autor:
Timothy F. Osborne, Adeline Divoux, Balint L. Balint, Dóra Bojcsuk, Amlan Talukder, Katalin Sandor, Xiaoman Li, Steven R. Smith
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-15 (2018)
Clinical Epigenetics
Clinical Epigenetics
Background Increased lower body fat is associated with reduced cardiometabolic risk. The molecular basis for depot-specific differences in gluteofemoral (GF) compared with abdominal (A) subcutaneous adipocyte function is poorly understood. In the cur