Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Adeline, Vulin"'
Autor:
Nicolas Wein, Tatyana A. Vetter, Adeline Vulin, Tabatha R. Simmons, Emma C. Frair, Adrienne J. Bradley, Liubov V. Gushchina, Camila F. Almeida, Nianyuan Huang, Daniel Lesman, Dhanarajan Rajakumar, Robert B. Weiss, Kevin M. Flanigan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 279-293 (2022)
Duchenne muscular dystrophy (DMD) is typically caused by mutations that disrupt the DMD reading frame, but nonsense mutations in the 5′ part of the gene induce utilization of an internal ribosomal entry site (IRES) in exon 5, driving expression of
Externí odkaz:
https://doaj.org/article/937ffb28cf15459caaa9793b8cebec7b
Autor:
Tabatha R. Simmons, Tatyana A. Vetter, Nianyuan Huang, Adeline Vulin-Chaffiol, Nicolas Wein, Kevin M. Flanigan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 325-340 (2021)
Duchenne muscular dystrophy (DMD) is an X-linked progressive disease characterized by loss of dystrophin protein that typically results from truncating mutations in the DMD gene. Current exon-skipping therapies have sought to treat deletion mutations
Externí odkaz:
https://doaj.org/article/6912488c4ecd404facb01ca8c3e269ec
Autor:
Inès Barthélémy, Nadège Calmels, Robert B. Weiss, Laurent Tiret, Adeline Vulin, Nicolas Wein, Cécile Peccate, Carole Drougard, Christophe Beroud, Nathalie Deburgrave, Jean-Laurent Thibaud, Catherine Escriou, Isabel Punzón, Luis Garcia, Jean-Claude Kaplan, Kevin M. Flanigan, France Leturcq, Stéphane Blot
Publikováno v:
Skeletal Muscle, Vol 10, Iss 1, Pp 1-22 (2020)
Abstract Background Canine models of Duchenne muscular dystrophy (DMD) are a valuable tool to evaluate potential therapies because they faithfully reproduce the human disease. Several cases of dystrophinopathies have been described in canines, but th
Externí odkaz:
https://doaj.org/article/4db5e8aca9c9431692a8b17b3323ddbf
Autor:
Tatyana A. Vetter, Nicolas Wein, Kevin M. Flanigan, Nianyuan Huang, Tabatha R. Simmons, Adeline Vulin-Chaffiol
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 325-340 (2021)
Duchenne muscular dystrophy (DMD) is an X-linked progressive disease characterized by loss of dystrophin protein that typically results from truncating mutations in the DMD gene. Current exon-skipping therapies have sought to treat deletion mutations
Autor:
Tabatha R, Simmons, Tatyana A, Vetter, Nianyuan, Huang, Adeline, Vulin-Chaffiol, Nicolas, Wein, Kevin M, Flanigan
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Duchenne muscular dystrophy (DMD) is an X-linked progressive disease characterized by loss of dystrophin protein that typically results from truncating mutations in the DMD gene. Current exon-skipping therapies have sought to treat deletion mutations
Autor:
Barthélémy Inès, Inès Barthelemy, Nadège Calmels, Robert B. Weiss, Laurent Tiret, Adeline Vulin, Nicolas Wein, Cécile Peccate, Carole Drougard, Christophe Beroud, Nathalie Deburgrave, Jean-Laurent Thibaud, Catherine Escriou, Isabel Punzon, Luis Garcia, Jean-Claude Kaplan, Kevin M. Flanigan, France Leturcq, Stéphane Blot
Background Canine models of Duchenne muscular dystrophy (DMD) are valuable to evaluate therapies because they faithfully reproduce the human disease. Several cases of dystrophinopathies have been described in canines, but the GRMD (Golden Retriever M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bb5be8758480e86dea57c8eb8cd7f57
https://doi.org/10.21203/rs.3.rs-16251/v1
https://doi.org/10.21203/rs.3.rs-16251/v1
Publikováno v:
Drugs
Drugs, Springer Verlag, In press, ⟨10.1007/s40265-020-01363-3⟩
Drugs, Springer Verlag, In press, ⟨10.1007/s40265-020-01363-3⟩
International audience; Neuromuscular disorders include a wide range of diseases affecting the peripheral nervous system, which are primarily characterized by progressive muscle weakness and wasting. While there were no effective therapies until rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3738ef86b43c2ff385943e4e75ea5635
https://hal.archives-ouvertes.fr/hal-02912701
https://hal.archives-ouvertes.fr/hal-02912701
Autor:
Jean-Laurent Thibaud, Christophe Béroud, Adeline Vulin, Kevin M. Flanigan, Nicolas Wein, Nathalie Deburgrave, Stéphane Blot, Jean-Claude Kaplan, Isabel Punzón, Laurent Tiret, Cécile Peccate, Robert B. Weiss, Catherine Escriou, Inès Barthélémy, Nadège Calmels, Luis Garcia, Carole Drougard
Publikováno v:
Skeletal Muscle
Skeletal Muscle, 2020, 10 (1), pp.23. ⟨10.1186/s13395-020-00239-0⟩
Skeletal Muscle, BioMed Central, 2020, 10 (1), pp.23. ⟨10.1186/s13395-020-00239-0⟩
Skeletal Muscle, Vol 10, Iss 1, Pp 1-22 (2020)
Skeletal Muscle, 2020, 10 (1), pp.23. ⟨10.1186/s13395-020-00239-0⟩
Skeletal Muscle, BioMed Central, 2020, 10 (1), pp.23. ⟨10.1186/s13395-020-00239-0⟩
Skeletal Muscle, Vol 10, Iss 1, Pp 1-22 (2020)
Background Canine models of Duchenne muscular dystrophy (DMD) are a valuable tool to evaluate potential therapies because they faithfully reproduce the human disease. Several cases of dystrophinopathies have been described in canines, but the Golden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3688323d713b671b97e2b41447f24486
https://hal.sorbonne-universite.fr/hal-02934725/document
https://hal.sorbonne-universite.fr/hal-02934725/document
Autor:
Adeline Vulin, Nicolas Wein, Steve D. Wilton, Felecia Gumienny, Nianyuan Huang, Andrew R. Findlay, Kevin M. Flanigan
Publikováno v:
Journal of Neuromuscular Diseases. 4:199-207
Background:Exon skipping strategies in Duchenne muscular dystrophy (DMD) have largely been directed toward altering splicing of exons flanking out-of-frame deletions, with the goal of restoring an open mRNA reading frame that leads to production of a
Publikováno v:
Martin, M T, Vulin, A & Hendry, J H 2016, ' Human epidermal stem cells : Role in adverse skin reactions and carcinogenesis from radiation ', Mutation Research-Reviews, vol. 770, pp. 349-368 . https://doi.org/10.1016/j.mrrev.2016.08.004
In human skin, keratinopoiesis is based on a functional hierarchy among keratinocytes, with rare slow-cycling stem cells responsible for the long-term maintenance of the tissue through their self-renewal potential, and more differentiated daughter pr