Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adelie Y S, Tan"'
Autor:
Florian Ermini, Victoria F. Low, Jennifer J. Song, Adelie Y. S. Tan, Richard L. M. Faull, Michael Dragunow, Maurice A. Curtis, Stephen S. Dominy
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Gingipains are protease virulence factors produced by Porphyromonas gingivalis, a Gram-negative bacterium best known for its role in chronic periodontitis. Gingipains were recently identified in the middle temporal gyrus of postmortem Alzhei
Externí odkaz:
https://doaj.org/article/e8b7aafa120347438648a23f9c4049de
Autor:
Florence E. Layburn, Adelie Y. S. Tan, Nasim F. Mehrabi, Maurice A. Curtis, Lynette J. Tippett, Nathan Riguet, Lorène Aeschbach, Hilal A. Lashuel, Mike Dragunow, Richard L. M. Faull, Malvindar K. Singh-Bains
Huntington’s disease (HD) is caused by a CAG repeat expansion mutation in the gene encoding the huntingtin (Htt) protein, with mutant Htt protein subsequently forming aggregates within the brain. Mutant Htt is a current target for novel therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::754ea9bcb712809b61a79184bb834350
https://doi.org/10.1101/2022.05.03.490349
https://doi.org/10.1101/2022.05.03.490349
Autor:
Richard L.M. Faull, Malvindar K. Singh-Bains, Nasim F. Mehrabi, Adelie Y. S. Tan, Mike Dragunow
Publikováno v:
Nature Protocols. 16:2308-2343
A major challenge in the treatment of neurodegenerative disorders is the translation of effective therapies from the lab to the clinic. One approach to improve this process is the use of human brain tissue microarray (HBTMA) technology to aid in the
Autor:
Tvesa Sehji, Lynette J. Tippett, Mike Dragunow, Richard L.M. Faull, Nasim F. Mehrabi, Henry J. Waldvogel, Adelie Y. S. Tan, Micah D. R. Austria, Malvindar K. Singh-Bains
Publikováno v:
Annals of Neurology
Objective Huntington disease (HD) is an autosomal dominant neurodegenerative disorder characterized by variable motor and behavioral symptoms attributed to major neuropathology of mainly the basal ganglia and cerebral cortex. The role of the cerebell
Autor:
Malvindar K, Singh-Bains, Nasim F, Mehrabi, Adelie Y S, Tan, Richard L M, Faull, Mike, Dragunow
Publikováno v:
Nature protocols. 16(4)
A major challenge in the treatment of neurodegenerative disorders is the translation of effective therapies from the lab to the clinic. One approach to improve this process is the use of human brain tissue microarray (HBTMA) technology to aid in the
Autor:
Vanessa Linke, Richard L.M. Faull, Emma L. Scotter, Nasim F. Mehrabi, Malvindar K. Singh-Bains, Micah D. R. Austria, Mike Dragunow, Adelie Y. S. Tan
Publikováno v:
Neurobiology of Disease, Vol 132, Iss, Pp-(2019)
Traditionally regarded to coordinate movement, the cerebellum also exerts non-motor functions including the regulation of cognitive and behavioral processing, suggesting a potential role in neurodegenerative conditions affecting cognition, such as Al
Autor:
Florence E, Layburn, Adelie Y S, Tan, Nasim F, Mehrabi, Maurice A, Curtis, Lynette J, Tippett, Clinton P, Turner, Nathan, Riguet, Lorène, Aeschbach, Hilal A, Lashuel, Mike, Dragunow, Richard L M, Faull, Malvindar K, Singh-Bains
Huntington's disease (HD) is caused by a CAG repeat expansion mutation in the gene encoding the huntingtin (Htt) protein, with mutant Htt protein subsequently forming aggregates within the brain. Mutant Htt is a current target for novel therapeutic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ee3c1478760134f05dcd9b78296648
https://infoscience.epfl.ch/record/298677
https://infoscience.epfl.ch/record/298677