Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Adelheid Korb"'
Autor:
Martin Aringer, Nicolai Leuchten, Adelheid Korb-Pap, Babett Heschel, Annika Krause, Martyna Hempel, Erik Klapproth, Ali El-Amouche
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/392d8230f84b4b15b88e3ceb41b54386
Autor:
Michelle Fennen, Toni Weinhage, Vanessa Kracke, Johanna Intemann, Georg Varga, Corinna Wehmeyer, Dirk Foell, Adelheid Korb-Pap, Thomas Pap, Berno Dankbar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The interactions of fibroblast-like synoviocyte (FLS)-derived pro-inflammatory cytokines/chemokines and immune cells support the recruitment and activation of inflammatory cells in RA. Here, we show for the first time that the classical myok
Externí odkaz:
https://doaj.org/article/0e68a05c59a446c9abd58a77cfaf8633
Autor:
Denise Beckmann, Anja Römer-Hillmann, Annika Krause, Uwe Hansen, Corinna Wehmeyer, Johanna Intemann, David J. J. de Gorter, Berno Dankbar, Jan Hillen, Marianne Heitzmann, Isabell Begemann, Milos Galic, Toni Weinhage, Dirk Foell, Rizi Ai, Joachim Kremerskothen, Hans P. Kiener, Sylvia Müller, Thomas Kamradt, Christopher Schröder, Elsa Leitão, Bernhard Horsthemke, Philip Rosenstiel, Karl Nordström, Gilles Gasparoni, Nina Gasparoni, Jörn Walter, Na Li, Xinyi Yang, Ho-Ryun Chung, Hermann Pavenstädt, Nico Lindemann, Hans J. Schnittler, Wei Wang, Gary S. Firestein, Thomas Pap, Adelheid Korb-Pap
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Fibroblast-like synoviocytes are important mediators of joint pathology in rheumatoid arthritis (RA). Here the authors show that Lasp1 is epigenetically regulated and highly expressed by these cells in RA and its deletion can limit joint pathology in
Externí odkaz:
https://doaj.org/article/6eeabbe32b3249c9843c922ebc496340
Autor:
Kerstin Göbel, Susann Pankratz, Chloi-Magdalini Asaridou, Alexander M. Herrmann, Stefan Bittner, Monika Merker, Tobias Ruck, Sarah Glumm, Friederike Langhauser, Peter Kraft, Thorsten F. Krug, Johanna Breuer, Martin Herold, Catharina C. Gross, Denise Beckmann, Adelheid Korb-Pap, Michael K. Schuhmann, Stefanie Kuerten, Ioannis Mitroulis, Clemens Ruppert, Marc W. Nolte, Con Panousis, Luisa Klotz, Beate Kehrel, Thomas Korn, Harald F. Langer, Thomas Pap, Bernhard Nieswandt, Heinz Wiendl, Triantafyllos Chavakis, Christoph Kleinschnitz, Sven G. Meuth
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Factor XII initiates the intrinsic blood coagulation cascade and the kinin system. Here the authors show that Factor XII is elevated in the blood of multiple sclerosis patients, activates dendritic cells via CD87 and cAMP, and its blockade inhibits i
Externí odkaz:
https://doaj.org/article/df39268cbc9348e48bfb9cdea92d808d
Publikováno v:
Integrins in Health and Disease ISBN: 9783031237805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7be2ea6498ad27ea69ae8169512d253f
https://doi.org/10.1007/978-3-031-23781-2_8
https://doi.org/10.1007/978-3-031-23781-2_8
Publikováno v:
Osteologie. 30:304-310
Rheumatoid arthritis (RA) is an immune mediated inflammatory disease (IMID), characterized by chronic inflammation and irreversible bone loss. Studies have shown that fibroblast-like synoviocytes (FLS), a key cell population in the pathogenesis of RA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18e7064ee749986acb37f3ad3be2ff78
https://doi.org/10.1055/a-1662-3449
https://doi.org/10.1055/a-1662-3449
Autor:
Adrian Deichsel, Anna De Giuseppe, Isabel Zeinert, Kerstin Rauwolf, Ning Lu, Denise Beckmann, Annika Krause, Beate Eckes, Uwe Hansen, Daniel Kronenberg, Donald Gullberg, Thomas Pap, Adelheid Korb-Pap
BackgroundIn rheumatoid arthritis (RA), fibroblast like synoviocytes (FLS) undergo a “tumor-like” transformation, wherein they develop an aggressive phenotype that is characterized by increased adhesion to components of cartilage extracellular ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6b16d9ed602d681ca8702ba0bee0f9d
https://doi.org/10.1101/2022.01.14.476301
https://doi.org/10.1101/2022.01.14.476301
Autor:
Vanessa Waltereit-Kracke, Corinna Wehmeyer, Denise Beckmann, Eugenie Werbenko, Julia Reinhardt, Fabienne Geers, Mike Dienstbier, Michelle Fennen, Johanna Intemann, Peter Paruzel, Adelheid Korb-Pap, Thomas Pap, Berno Dankbar
Publikováno v:
Annals of the rheumatic diseases. 81(8)
ObjectiveThe aim of this study was to assess the extent and the mechanism by which activin A contributes to progressive joint destruction in experimental arthritis and which activin A-expressing cell type is important for disease progression.MethodsL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0213edcba31a7576446349fc61897449
https://pubmed.ncbi.nlm.nih.gov/35418478
https://pubmed.ncbi.nlm.nih.gov/35418478
Autor:
Rizi Ai, Uwe Hansen, Johanna Intemann, Elsa Leitão, Toni Weinhage, Isabell Begemann, Joachim Kremerskothen, Anja Römer-Hillmann, Ho-Ryun Chung, Marianne Heitzmann, Thomas Pap, Hermann Pavenstädt, Hans P. Kiener, Na Li, Annika Krause, Wei Wang, Gilles Gasparoni, Berno Dankbar, Sylvia Müller, Corinna Wehmeyer, Denise Beckmann, Dirk Foell, Philip Rosenstiel, Bernhard Horsthemke, Thomas Kamradt, Adelheid Korb-Pap, Karl Nordström, Hans Schnittler, David J. J. de Gorter, Nico Lindemann, Jörn Walter, Gary S. Firestein, Xinyi Yang, Nina Gasparoni, Christopher Schröder, Jan Hillen, Milos Galic
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The LIM and SH3 domain protein 1 (Lasp1) was originally cloned from metastatic breast cancer and characterised as an adaptor molecule associated with tumourigenesis and cancer cell invasion. However, the regulation of Lasp1 and its function in the ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186d00758ac40be110c81701778639ee
http://europepmc.org/articles/PMC8206096
http://europepmc.org/articles/PMC8206096
Autor:
Arif B. Ekici, Tobias Bäuerle, Fabian T. Andes, Georg Schett, Adam P. Croft, Andreas Hess, Jasna Friščić, Oliver Aust, Hans P. Kiener, Christopher D. Buckley, Dimitrios Mougiakakos, Jochen A. Ackermann, Martin Böttcher, Jason D. Turner, Arnd Kleyer, Johnathan Winter, Jörg H W Distler, René Krüger, Viktor Wixler, Lisa Seyler, Ulrike Steffen, Karim Raza, Maximilien Euler, Benjamin Wirth, Triin Major, Heiko Bruns, Isabel Wank, Silke Frey, Kellie Irene Walker, Daniela Weidner, Timothy R. Hughes, Christiane Reinwald, Anita Fischer, Zeljka Stanojevic, Günter Steiner, Martin Herrmann, Samantha-Josefine Popp, Gerhard Krönke, Lasse Kling, Andrew Filer, Xi Chen, Jörg Köhl, Anika Grüneboom, Honglin Zhu, Vladimir Trajkovic, Adelheid Korb-Pap, Katja Klein, Benjamin Frey, Philipp Kirchner, Markus H. Hoffmann
Publikováno v:
Immunity
Arthritis typically involves recurrence and progressive worsening at specific predilection sites, but the checkpoints between remission and persistence remain unknown. Here, we defined the molecular and cellular mechanisms of this inflammation-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2342f4745cc2e6da2c890dd8134a377
https://pubmed.ncbi.nlm.nih.gov/33979581
https://pubmed.ncbi.nlm.nih.gov/33979581