Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Adele Guglielmi"'
Autor:
Eltahir Ali, Rosalba Monica Ferraro, Adele Guglielmi, Gaetana Lanzi, Stefania Masneri, Giovanna Piovani, Elena Laura Mazzoldi, Lidia Pollara, Enza Maria Valente, Patrizia Accorsi, Lucio Giordano, Silvia Clara Giliani
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102430- (2021)
We have developed Joubert syndrome (JS)-derived induced pluripotent stem cell (iPSC) lines from dermal fibroblasts biopsied from a female patient harbouring novel compound heterozygous mutations in CC2D2A gene. The newly established iPSC lines provid
Externí odkaz:
https://doaj.org/article/148541f6e03e45fb8c8053574f7d14b5
Autor:
Federica Bono, Veronica Mutti, Giovanna Piovani, Alessandra Minelli, Jessica Mingardi, Adele Guglielmi, Cristina Missale, Massimo Gennarelli, Chiara Fiorentini, Alessandro Barbon
Publikováno v:
Stem Cell Research, Vol 51, Iss , Pp 102216- (2021)
Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs
Externí odkaz:
https://doaj.org/article/0086af8d88b1439ebf4d340d8d35ec00
Autor:
Federica Bono, Veronica Mutti, Giovanna Piovani, Alessandra Minelli, Jessica Mingardi, Adele Guglielmi, Chiara Fiorentini, Alessandro Barbon, Cristina Missale, Massimo Gennarelli
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102104- (2020)
Novel and complementary experimental models are required for investigating the molecular mechanisms underlying the resistance to the available therapies of patients with major depression (Treatment-Resistant Depression, TRD) that occurs in at least o
Externí odkaz:
https://doaj.org/article/96aafb4aed6e4e63b748010819b98fad
Autor:
Daniela Zizioli, Natascia Tiso, Adele Guglielmi, Claudia Saraceno, Giorgia Busolin, Roberta Giuliani, Deepak Khatri, Eugenio Monti, Giuseppe Borsani, Francesco Argenton, Dario Finazzi
Publikováno v:
Neurobiology of Disease, Vol 85, Iss , Pp 35-48 (2016)
ABSTRACT: Pantothenate Kinase Associated Neurodegeneration (PKAN) is an autosomal recessive disorder with mutations in the pantothenate kinase 2 gene (PANK2), encoding an essential enzyme for Coenzyme A (CoA) biosynthesis. The molecular connection be
Externí odkaz:
https://doaj.org/article/fbb3bc3650774261af792211cf7b098c
Autor:
Veronica Mutti, Federica Bono, Zaira Tomasoni, Leonardo Bontempi, Adele Guglielmi, Silvia Bolognin, Jens C. Schwamborn, Cristina Missale, Chiara Fiorentini
Publikováno v:
Molecular Neurobiology. 59:2129-2149
We have previously shown that the heteromer composed by the dopamine D3 receptor (D3R) and the nicotinic acetylcholine receptor (nAChR) (D3R-nAChR heteromer) is expressed in dopaminergic neurons, activated by nicotine and represents the molecular uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a0377aa950447769ecb06b9e41b132
https://doi.org/10.1007/s12035-022-02748-z
https://doi.org/10.1007/s12035-022-02748-z
Autor:
Joan Tymon-Rosario, Gloria S. Huang, Burak Zeybek, Adele Guglielmi, Stefania Bellone, Peter E. Schwartz, Paola Manara, Elena Bonazzoli, Barbara Gnutti, Nupur Nagarkatti, Vaagn Andikyan, Elena Ratner, Alessandro D. Santin, Gary Altwerger, Silvia Pelligra, Dan-Arin Silasi, Luca Zammataro, Chanhee Han, Masoud Azodi, Gulden Menderes
Publikováno v:
Gynecol Oncol
Objective Whole-exome-sequencing (WES) studies reported c-MYC gene-amplification and HUWE1 gene deletion/mutations in a significant number of cervical-cancer-patients (CC) suggesting HUWE1/c-MYC pathway as potential therapeutic target. We investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c059e7f84744067afdc1b4c93ed309
https://doi.org/10.1016/j.ygyno.2020.06.484
https://doi.org/10.1016/j.ygyno.2020.06.484
Autor:
Pei Hui, Elena Ratner, Peter E. Schwartz, Masoud Azodi, Natalia Buza, Stefania Bellone, Paola Manara, Burak Zeybek, Mitchell Clark, Aranzazu Manzano, Gary Altwerger, Silvia Pelligra, Elena Bonazzoli, Gulden Menderes, Luca Zammataro, Dennis Mauricio, Gloria S. Huang, Barbara Gnutti, Justin Harold, Vaagn Andikyan, Nupur Nagarkatti, Alessandro D. Santin, Adele Guglielmi, Dan-Arin Silasi, Joan Tymon-Rosario
Publikováno v:
Gynecol Oncol
OBJECTIVE: Uterine serous carcinoma (USC) is an aggressive histologic variant of endometrial cancer which portends a poor prognosis. DHES0815A is a novel antibody-drug-conjugate (ADC) which binds specifically to HER2 overexpressing tumors at a distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cc223ce756b3383cec909a8f83f8c1
https://europepmc.org/articles/PMC8722447/
https://europepmc.org/articles/PMC8722447/
Autor:
Stefania Bellone, Dana M. Roque, Eric R. Siegel, Natalia Buza, Pei Hui, Elena Bonazzoli, Adele Guglielmi, Luca Zammataro, Nupur Nagarkatti, Samir Zaidi, Jungsoo Lee, Dan‐Arin Silasi, Gloria S. Huang, Vaagn Andikyan, Shari Damast, Mitchell Clark, Masoud Azodi, Peter E. Schwartz, Joan R. Tymon‐Rosario, Justin A. Harold, Dennis Mauricio, Burak Zeybek, Gulden Menderes, Gary Altwerger, Elena Ratner, Ludmil B. Alexandrov, Akiko Iwasaki, Yong Kong, Eric Song, Weilai Dong, Julia A. Elvin, Jungmin Choi, Alessandro D. Santin
Publikováno v:
Cancer. 128(6)
Microsatellite instability-high (MSI-H)/mismatch repair deficiency (dMMR) is a biomarker for responses to immune checkpoint inhibitors (ICIs). Whether mechanisms underlying microsatellite instability alter responses to ICIs is unclear. This article r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975deb9e7d004ce47026eeda6efd6908
https://pubmed.ncbi.nlm.nih.gov/34875102
https://pubmed.ncbi.nlm.nih.gov/34875102
Autor:
Veronica Mutti, Jessica Mingardi, Massimo Gennarelli, Adele Guglielmi, Cristina Missale, Federica Bono, Alessandro Barbon, Chiara Fiorentini, Alessandra Minelli, Giovanna Piovani
Publikováno v:
Stem Cell Research, Vol 51, Iss, Pp 102216-(2021)
Peripheral blood mononuclear cells (PBMCs) derived from a healthy 40-year-old female were successfully transformed into induced pluripotent stem cells (iPSCs) by using the integration-free CytoTune-iPS Sendai Reprogramming method. The resulting iPSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7baa01078ee71803f0d35140f799cca5
http://www.sciencedirect.com/science/article/pii/S1873506121000623
http://www.sciencedirect.com/science/article/pii/S1873506121000623
Autor:
Franco Odicino, Samir Zaidi, Nupur Nagarkatti, Gary Altwerger, Laura Zanotti, Alessandro D. Santin, Elena Bonazzoli, Kyungjo Jeong, Gloria S. Huang, Dan-Arin Silasi, Adele Guglielmi, Burak Zeybek, Richard P. Lifton, Luca Zammataro, Dennis Mauricio, Aranzazu Manzano, Gulden Menderes, Barbara Gnutti, Justin Harold, Siming Zhao, Laura Ardighieri, Jungmin Choi, Vaagn Andikyan, Elena Ratner, Chiara Romani, Pei Hui, Xiaotong Yao, Eliana Bignotti, Antonella Ravaggi, Masoud Azodi, Stefania Bellone, Joseph Schlessinger, Joan Tymon-Rosario, Natalia Buza, Ludmil B. Alexandrov, Weilai Dong, Paola Todeschini, Marcin Imielinski, Kaya Bilguvar, Mitchell Clark, Peter E. Schwartz, Charles M. Quick, Sergio Pecorelli, Aditya Deshpande
Publikováno v:
Proc Natl Acad Sci U S A
Uterine leiomyosarcomas (uLMS) are aggressive tumors arising from the smooth muscle layer of the uterus. We analyzed 83 uLMS sample genetics, including 56 from Yale and 27 from The Cancer Genome Atlas (TCGA). Among them, a total of 55 Yale samples in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29b1daa57773373079eeec2397f029d
https://hdl.handle.net/11379/568771
https://hdl.handle.net/11379/568771