Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Adele Gabriele Marthaler"'
Publikováno v:
Stem Cell Reports, Vol 6, Iss 1, Pp 35-43 (2016)
Somatic cells can be reprogrammed to pluripotency using different methods. In comparison with pluripotent cells obtained through somatic nuclear transfer, induced pluripotent stem cells (iPSCs) exhibit a higher number of epigenetic errors. Furthermor
Externí odkaz:
https://doaj.org/article/e9e2b7df486e477ebf8670ab92251d29
Autor:
Ulf Tiemann, Adele Gabriele Marthaler, Kenjiro Adachi, Guangming Wu, Gerrit Ulf Lennart Fischedick, Marcos Jesús Araúzo-Bravo, Hans Robert Schöler, Natalia Tapia
Publikováno v:
Stem Cell Reports, Vol 2, Iss 3, Pp 351-365 (2014)
Differentiated cells can be reprogrammed into induced pluripotent stem cells (iPSCs) after overexpressing four transcription factors, of which Oct4 is essential. To elucidate the role of Oct4 during reprogramming, we investigated the immediate transc
Externí odkaz:
https://doaj.org/article/7f804055fa2b47a08e6d88b98eadab35
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 6, Iss 1, Pp 35-43 (2016)
Stem Cell Reports, Vol 6, Iss 1, Pp 35-43 (2016)
Summary Somatic cells can be reprogrammed to pluripotency using different methods. In comparison with pluripotent cells obtained through somatic nuclear transfer, induced pluripotent stem cells (iPSCs) exhibit a higher number of epigenetic errors. Fu
Autor:
Hans R. Schöler, Kenjiro Adachi, Natalia Tapia, Guangming Wu, Marcos J. Araúzo-Bravo, Adele Gabriele Marthaler, Gerrit Fischedick, Ulf Tiemann
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 2, Iss 3, Pp 351-365 (2014)
Stem Cell Reports, Vol 2, Iss 3, Pp 351-365 (2014)
Summary Differentiated cells can be reprogrammed into induced pluripotent stem cells (iPSCs) after overexpressing four transcription factors, of which Oct4 is essential. To elucidate the role of Oct4 during reprogramming, we investigated the immediat
Autor:
Davood Sabour, Sergiy Velychko, Adele Gabriele Marthaler, Kenjiro Adachi, Guangming Wu, Natalia Tapia, Ulf Tiemann, Ingo Kleiter, Hans R. Schöler
Publikováno v:
Scientific Reports
Adenoviral early region 1A (E1A) is a viral gene that can promote cellular proliferation and de-differentiation in mammalian cells, features required for the reprogramming of somatic cells to a pluripotent state. E1A has been shown to interact with O
Autor:
Hans R. Schöler, Vlad Cojocaru, Ralf Jauch, Daniel Esch, Natalia Tapia, Adele Gabriele Marthaler, Caitlin M. MacCarthy, Ulf Tiemann, Marcos J. Araúzo-Bravo
Publikováno v:
Scientific Reports
The transcription factors OCT4 and SOX2 are required for generating induced pluripotent stem cells (iPSCs) and for maintaining embryonic stem cells (ESCs). OCT4 and SOX2 associate and bind to DNA in different configurations depending on the arrangeme