Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Adele Finardi"'
Autor:
Paola Nobili, Francesca Colciaghi, Adele Finardi, Sara Zambon, Denise Locatelli, Giorgio Stefano Battaglia
Publikováno v:
Neurobiology of Disease, Vol 83, Iss , Pp 54-66 (2015)
Whether seizures might determine the activation of cell death pathways and what could be the relevance of seizure-induced cell death in epilepsy are still highly debated issues. We recently developed an experimental model of acquired focal cortical d
Externí odkaz:
https://doaj.org/article/fc87f2c5c49e415e92aec6bb21942c31
Autor:
Daniela Pletto, Silvia Capra, Adele Finardi, Francesca Colciaghi, Paola Nobili, Giorgio Stefano Battaglia, Denise Locatelli, Cinzia Cagnoli
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199105 (2018)
Spinal Muscular Atrophy (SMA) is a severe autosomal recessive disease characterized by selective motor neuron degeneration, caused by disruptions of the Survival of Motor Neuron 1 (Smn1) gene. The main product of SMN1 is the full-length SMN protein (
Externí odkaz:
https://doaj.org/article/da9d6add2f674cbe9eeca9ceb75941bc
Autor:
Stefania Bassanini, Kerri Hallene, Giorgio Battaglia, Adele Finardi, Stefano Santaguida, Marilyn Cipolla, Damir Janigro
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 2, Pp 481-495 (2007)
One of the most common causes of neurological disabilities are malformations of cortical development (MCD). A useful animal model of MCD consists of prenatal exposure to methylazoxymethanol (MAM), resulting in a postnatal phenotype characterized by c
Externí odkaz:
https://doaj.org/article/cf8189f2fd494e1da92cb4df7e76d25f
Autor:
Denise Locatelli, Mineko Terao, Mami Kurosaki, Maria Clara Zanellati, Daniela Rita Pletto, Adele Finardi, Francesca Colciaghi, Enrico Garattini, Giorgio Stefano Battaglia
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134163 (2015)
The key pathogenic steps leading to spinal muscular atrophy (SMA), a genetic disease characterized by selective motor neuron degeneration, are not fully clarified. The full-length SMN protein (FL-SMN), the main protein product of the disease gene SMN
Externí odkaz:
https://doaj.org/article/26650bee719c4bea9a74edffa97d6c8d
Autor:
Francesca Colciaghi, Adele Finardi, Paola Nobili, Denise Locatelli, Giada Spigolon, Giorgio Stefano Battaglia
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89898 (2014)
Whether severe epilepsy could be a progressive disorder remains as yet unresolved. We previously demonstrated in a rat model of acquired focal cortical dysplasia, the methylazoxymethanol/pilocarpine - MAM/pilocarpine - rats, that the occurrence of st
Externí odkaz:
https://doaj.org/article/437457bae5ab4775abec7a1252dde6e4
Autor:
Annarita Tagliaferri, Angelo Claudio Molinari, Flora Peyvandi, Antonio Coppola, Francesco Demartis, Chiara Biasoli, Alessandra Borchiellini, Dorina Cultrera, Raimondo De Cristofaro, Filomena Daniele, Paola Giordano, Emanuela Marchesini, Maurizio Margaglione, Renato Marino, Berardino Pollio, Paolo Radossi, Cristina Santoro, Rita Carlotta Santoro, Sergio Siragusa, Gianluca Sottilotta, Alberto Tosetto, Lydia Piscitelli, Maria Rosaria Villa, Ezio Zanon, Adele Finardi, Irene Schiavetti, Daniella Vaccari, Giancarlo Castaman
Publikováno v:
Haemophilia. 29:135-144
Introduction: Factor IX replacement therapy is used for treatment and prophylaxis of bleeding in haemophilia B. rIX-FP is an extended half-life albumin-fusion protein, which, in clinical studies, has demonstrated prolonged dosing intervals up to 21 d
Autor:
Francesca Colciaghi, Paola Nobili, Adele Finardi, Denise Locatelli, Sara Zambon, Giorgio Battaglia
Publikováno v:
Neurobiology of Disease, Vol 83, Iss, Pp 54-66 (2015)
Whether seizures might determine the activation of cell death pathways and what could be the relevance of seizure-induced cell death in epilepsy are still highly debated issues. We recently developed an experimental model of acquired focal cortical d
Autor:
Francesca Colciaghi, Denise Locatelli, Daniela Rita Pletto, Adele Finardi, Giorgio Battaglia, Paola Nobili, Cinzia Cagnoli, Silvia Capra
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199105 (2018)
Spinal Muscular Atrophy (SMA) is a severe autosomal recessive disease characterized by selective motor neuron degeneration, caused by disruptions of the Survival of Motor Neuron 1 (Smn1) gene. The main product of SMN1 is the full-length SMN protein (
The present chapter reviews the methyl-azoxy-methanol acetate (MAM) acquired “lesion” model, that is, experimental animals in which structural and persistent brain abnormalities are induced by prenatal exposition to the neurotoxin MAM. MAM is abl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2269dd328e7193931c4bf3a34ff638
https://doi.org/10.1016/b978-0-12-804066-9.00058-4
https://doi.org/10.1016/b978-0-12-804066-9.00058-4
Publikováno v:
Epilepsia. 54:33-36
Focal cortical dysplasia (FCD) is a brain malformation associated with particularly severe drug-resistant epilepsy that often requires surgery for seizure control. The molecular basis for such enhanced propensity to seizure generation in FCD is not a