Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adelaide I J Young"'
Autor:
Samantha R Oakes, David Gallego-Ortega, Prudence M Stanford, Simon Junankar, Wendy Wing Yee Au, Zoya Kikhtyak, Anita von Korff, Claudio M Sergio, Andrew M K Law, Lesley E Castillo, Stephanie L Allerdice, Adelaide I J Young, Catherine Piggin, Belinda Whittle, Edward Bertram, Matthew J Naylor, Daniel L Roden, Jesse Donovan, Alexei Korennykh, Christopher C Goodnow, Moira K O'Bryan, Christopher J Ormandy
Publikováno v:
PLoS Genetics, Vol 13, Iss 11, p e1007072 (2017)
We identified a non-synonymous mutation in Oas2 (I405N), a sensor of viral double-stranded RNA, from an ENU-mutagenesis screen designed to discover new genes involved in mammary development. The mutation caused post-partum failure of lactation in hea
Externí odkaz:
https://doaj.org/article/76d21e2f20924475a4c47cb697a95a92
Autor:
David Gallego-Ortega, Anita Ledger, Daniel L Roden, Andrew M K Law, Astrid Magenau, Zoya Kikhtyak, Christina Cho, Stephanie L Allerdice, Heather J Lee, Fatima Valdes-Mora, David Herrmann, Robert Salomon, Adelaide I J Young, Brian Y Lee, C Marcelo Sergio, Warren Kaplan, Catherine Piggin, James R W Conway, Brian Rabinovich, Ewan K A Millar, Samantha R Oakes, Tatyana Chtanova, Alexander Swarbrick, Matthew J Naylor, Sandra O'Toole, Andrew R Green, Paul Timpson, Julia M W Gee, Ian O Ellis, Susan J Clark, Christopher J Ormandy
Publikováno v:
PLoS Biology, Vol 13, Iss 12, p e1002330 (2015)
During pregnancy, the ETS transcription factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of the mammary luminal progenitor cell. In breast cancer, ELF5 is a key transcriptional determinant of tumor subt
Externí odkaz:
https://doaj.org/article/eb537bc34b10404fbde06ea888ba833f
Autor:
Jana Travnickova, Sarah Muise, Sonia Wojciechowska, Alessandro Brombin, Zhiqiang Zeng, Adelaide I. J. Young, Cameron Wyatt, E. Elizabeth Patton
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/0a137db18d544d568bdd288bdfc82e02
Autor:
Adelaide I. J. Young, Paul Timpson, Amanda Mawson, Ashleigh Parkin, Danielle Nessem, David Gallego-Ortega, Pia Schafranek, Samantha R. Oakes, Catherine E Caldon, Angela Steinmann, Andrew M. K. Law, Angela Chou, Niantao Deng, Christopher J. Ormandy, Morghan C. Lucas, Lesley Castillo, Marina Pajic, Kendelle J. Murphy, Amber L. Johns
Publikováno v:
Oncogene
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies. It is phenotypically heterogeneous with a highly unstable genome and provides few common therapeutic targets. We found that MCL1, Cofilin1 (CFL1) and SRC mRNA were hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bbd8992ce18e36adc02f31e5d4a292
http://europepmc.org/articles/PMC7033042
http://europepmc.org/articles/PMC7033042
Autor:
Catherine E Caldon, Andrew M. K. Law, Sandra A O'Toole, Andrew Burgess, Lesley Castillo, Julia X. M. Yin, Samuel Rogers, David Gallego-Ortega, Ewan K.A. Millar, Christopher J. Ormandy, Catherine L. Piggin, Samantha R. Oakes, Adelaide I. J. Young
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Quantification of cellular antigens and their interactions via antibody-based detection methods are widely used in scientific research. Accurate high-throughput quantitation of these assays using general image analysis software can be time consuming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a353ebe7fef2cc1cfd60a8aec380fd9a
https://doi.org/10.1038/s41598-017-15885-6
https://doi.org/10.1038/s41598-017-15885-6
Autor:
Wendy Wing Yee Au, Samantha R. Oakes, Belinda Whittle, Jesse Donovan, Matthew J. Naylor, Christopher J. Ormandy, Zoya Kikhtyak, David Gallego-Ortega, Andrew M. K. Law, Stephanie L. Allerdice, Adelaide I. J. Young, Christopher C. Goodnow, Simon Junankar, Anita von Korff, Claudio M Sergio, Edward M. Bertram, Moira K O'Bryan, Lesley Castillo, Catherine L. Piggin, Daniel L. Roden, Prudence M Stanford, Alexei Korennykh
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 11, p e1007072 (2017)
PLoS Genetics, Vol 13, Iss 11, p e1007072 (2017)
We identified a non-synonymous mutation in Oas2 (I405N), a sensor of viral double-stranded RNA, from an ENU-mutagenesis screen designed to discover new genes involved in mammary development. The mutation caused post-partum failure of lactation in hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536ed1c723b111319265e7046d2dee2b
http://europepmc.org/articles/PMC5695588
http://europepmc.org/articles/PMC5695588
Autor:
Sabrina Chong, Paul Timpson, Lesley Castillo, David Herrmann, Erinna F. Lee, Ewan K.A. Millar, Amr H. Allam, Adelaide I. J. Young, Morghan C. Lucas, Hayley Daniella Cullen, Andrew M. K. Law, Tilman Brummer, Sebastian Herzog, Martin Koehler, W.D. Fairlie, David Gallego-Ortega, Christopher J. Ormandy, D. Neil Watkins, Sandra A O'Toole, Samantha R. Oakes
Publikováno v:
Breast Cancer Research : BCR
Background Metastatic disease is largely resistant to therapy and accounts for almost all cancer deaths. Myeloid cell leukemia-1 (MCL-1) is an important regulator of cell survival and chemo-resistance in a wide range of malignancies, and thus its inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c629349743432082026c46d23aa19dd3
https://pubmed.ncbi.nlm.nih.gov/27931239
https://pubmed.ncbi.nlm.nih.gov/27931239
Autor:
Brian Y. Lee, Paul Timpson, Anita Ledger, Andrew M. K. Law, Andrew R. Green, Robert Salomon, Samantha R. Oakes, Matthew J. Naylor, Fatima Valdes-Mora, Ewan K.A. Millar, Alexander Swarbrick, C. Marcelo Sergio, Zoya Kikhtyak, Brian Rabinovich, Catherine L. Piggin, Christina Cho, Adelaide I. J. Young, Sandra A O'Toole, Susan J. Clark, Warren Kaplan, Christopher J. Ormandy, Julia Margaret Wendy Gee, James R.W. Conway, Tatyana Chtanova, Astrid Magenau, Heather J. Lee, David Herrmann, David Gallego-Ortega, Ian O. Ellis, Daniel L. Roden, Stephanie L. Allerdice
Publikováno v:
PLoS Biology, Vol 13, Iss 12, p e1002330 (2015)
PLoS Biology
PLoS Biology
During pregnancy, the ETS transcription factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of the mammary luminal progenitor cell. In breast cancer, ELF5 is a key transcriptional determinant of tumor subt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4619fbcae1e0a1c74834015d6b3371
https://doi.org/10.1371/journal.pbio.1002330
https://doi.org/10.1371/journal.pbio.1002330