Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Adela Herraiz-Martínez"'
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Akademický článek
Novel PITX2 Homeodomain-Contained Mutations from ATRIAL Fibrillation Patients Deteriorate Calcium Homeostasis
Autor: Adela Herraiz-Martínez, Carmen Tarifa, Estefanía Lozano-Velasco, Verónica Jiménez-Sábado, Sergi Casabella, Francisco Hernández-Torres, Houria Daimi, Eduardo Vázquez Ruiz de Castroviejo, Eva Delpón, Ricardo Caballero, Amelia Aránega, Diego Franco, Leif Hove-Madsen
Publikováno v: Hearts, Vol 2, Iss 2, Pp 251-269 (2021)
Atrial fibrillation (AF) is the most common cardiac arrhythmia in the human population, with an estimated incidence of 1–2% in young adults but increasing to more than 10% in 80+ years patients. Pituitary Homeobox 2, Paired Like Homeodomain 2 (PITX
Externí odkaz: https://doaj.org/article/9224574e5f08470d8fa59729b239bd71
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3
Pitx2c deficiency confers cellular electrophysiological hallmarks of atrial fibrillation to isolated atrial myocytes
Autor: Carmen Tarifa, Selma A. Serra, Adela Herraiz-Martínez, Estefanía Lozano-Velasco, Raul Benítez, Amelia Aranega, Diego Franco, Leif Hove-Madsen
Aims Atrial fibrillation (AF) has been associated with altered expression of the transcription factor Pitx2c and a high incidence of calcium release-induced afterdepolarizations. However, the relationship between Pitx2c expression and defective calci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5b6abe5dabf99ae17ad77a242e3bd4
https://hdl.handle.net/2117/389927
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4
Influence of sex on intracellular calcium homoeostasis in patients with atrial fibrillation
Autor: Carmen Tarifa, Paloma Izquierdo-Castro, Raul Benitez, Carme Nolla-Colomer, Xavier Viñolas, Elena Roselló-Díez, Sergi Casabella, Iván Benítez, V Jimenez-Sabado, Juan Cinca, Leif Hove-Madsen, Francisco Ciruela, Enrique Rodríguez-Font, Hector Godoy-Marín, Anna Llach, Adela Herraiz-Martínez, H Colino
Publikováno v: CARDIOVASCULAR RESEARCH
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Digital.CSIC. Repositorio Institucional del CSIC
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Aims Atrial fibrillation (AF) has been associated with intracellular calcium disturbances in human atrial myocytes, but little is known about the potential influence of sex and we here aimed to address this issue. Methods and results Alterations in c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eccfa78aac1beeccf75a32635236468
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7770
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5
β2‐adrenergic stimulation potentiates spontaneous calcium release by increasing signal mass and co‐activation of ryanodine receptor clusters
Autor: Raul Benitez, Sergi Casabella‐Ramon, Leif Hove-Madsen, Juan Cinca, Anna Llach, Manel Tauron, Adela Herraiz-Martínez, Carme Nolla-Colomer, Alexander Vallmitjana, S.R. Wayne Chen, José Maria Montiel, Carmen Tarifa, V Jimenez-Sabado
Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Aims: It is unknown how ß-adrenergic stimulation affects calcium dynamics in individual RyR2 clusters and leads to the induction of spontaneous calcium waves. To address this, we analysed spontaneous calcium release events in green fluorescent prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1da49d194c159cf11dd02ab46778c9
https://doi.org/10.1111/apha.13736
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6
Novel PITX2 Homeodomain-Contained Mutations from ATRIAL Fibrillation Patients Deteriorate Calcium Homeostasis
Autor: Carmen Tarifa, Eduardo Vázquez Ruiz de Castroviejo, V Jimenez-Sabado, Adela Herraiz-Martínez, Francisco Hernández-Torres, Ricardo Caballero, Houria Daimi, Leif Hove-Madsen, Eva Delpón, Diego Franco, Sergi Casabella, Estefanía Lozano-Velasco, Amelia Aránega
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Hearts
Volume 2
Issue 2
Pages 20-271
Hearts, Vol 2, Iss 20, Pp 251-269 (2021)
Atrial fibrillation (AF) is the most common cardiac arrhythmia in the human population, with an estimated incidence of 1–2% in young adults but increasing to more than 10% in 80+ years patients. Pituitary Homeobox 2, Paired Like Homeodomain 2 (PITX
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49479e13199138f9df51e0c9ca79534d
http://hdl.handle.net/10261/264567
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7
Detection of calcium release from individual RyR2 clusters in cardiomyocites
Autor: Adela Herraiz Martínez, Leif Hove-Madsen, Carme Nolla Colomer, Hildegard Colino Lage, Alexander Vallmitjana, Raul Benitez, S.R. Wayne Chen
Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Cardiac ryanodine receptors (RyR2s) are Ca2þ release channels clustering in the sarcoplasmic reticulum membrane. These clusters are believed to be the elementary units of Ca2þ release. The distribution of these Ca2þ release units plays a critical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d202e7af86827bdb1e01ae5693db9f
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8
Neuron-derived orphan receptor-1 modulates cardiac gene expression and exacerbates angiotensin II-induced cardiac hypertrophy
Autor: J. A. Alonso, Leif Hove-Madsen, Jesús Osada, Carme Ballester-Servera, Laia Cañes, María Galán, Ingrid Martí-Pàmies, Adela Herraiz-Martínez, José Martínez-González, J. Francisco Nistal, Cristina Rodríguez, Pedro Muniesa
Publikováno v: CLINICAL SCIENCE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Digital.CSIC. Repositorio Institucional del CSIC
Hypertensive cardiac hypertrophy (HCH) is a common cause of heart failure (HF), a major public health problem worldwide. However, the molecular bases of HCH have not been completely elucidated. Neuron-derived orphan receptor-1 (NOR-1) is a nuclear re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef49a5ea50d8a7fe7fc0996a02890ae
https://pubmed.ncbi.nlm.nih.gov/31985010
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9
P1233Differential effects of five risk variants for atrial fibrillation at the 4q25 region on L-type calcium current and transient inward currents in human atrial myocytes
Autor: Juan Cinca, V Jimenez-Sabado, E Rodriguez-Font, Leif Hove-Madsen, Adela Herraiz-Martínez, Diego Franco, Carmen Tarifa, E Lozano-Velazquez, Anna Llach, H Colino, E Rosello
Publikováno v: European Heart Journal. 40
Background An increasing number of single nucleotide polymorphisms (SNPs) at the chromosomal region 4q25 have been associated with risk of atrial fibrillation (AF) and we have recently reported that carriers of the rs13143308 risk variant have an inc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ba8fe52338eff78575b257a0220ad86
https://doi.org/10.1093/eurheartj/ehz748.0191
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10
P3830Carvedilol treatment diminishes spontaneous calcium release and electrical activity in human atrial myocytes
Autor: Sergi Casabella, A Ginel, V Jimenez-Sabado, Juan Cinca, H Colino, Leif Hove-Madsen, T Lu, Adela Herraiz-Martínez, Carmen Tarifa, Anna Llach
Publikováno v: European Heart Journal. 40
Background Atrial fibrillation (AF) has been associated with an increase in spontaneous calcium release induced electrical activity, which could potentially be reversed by carvedilol, a nonselective beta-blocker that also inhibits the cardiac ryanodi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91f2317b92d22d4a524ce6e2835b0035
https://doi.org/10.1093/eurheartj/ehz745.0672
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