Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Adela Escudero"'
Autor:
Marta Ibáñez-Navarro, Adrián Fernández, Adela Escudero, Gloria Esteso, Carmen Campos-Silva, Miguel Ángel Navarro-Aguadero, Alejandra Leivas, Beatriz Ruz Caracuel, Carlos Rodríguez-Antolín, Alejandra Ortiz, Alfonso Navarro-Zapata, Carmen Mestre-Durán, Manuel Izquierdo, María Balaguer-Pérez, Cristina Ferreras, Joaquín Martínez-López, Mar Valés-Gómez, Antonio Pérez-Martínez, Lucía Fernández
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionRefractory/relapsed pediatric acute leukemia are still clinically challenging and new therapeutic strategies are needed. Interactions between Natural Killer Group 2D (NKG2D) receptor, expressed in cytotoxic immune cells, and its ligands (
Externí odkaz:
https://doaj.org/article/a050597990ec4b1fb78353f27eb60db9
Autor:
Pablo Velasco, Francisco Bautista, Alba Rubio, Yurena Aguilar, Susana Rives, Jose L. Dapena, Antonio Pérez, Manuel Ramirez, Cristina Saiz-Ladera, Elisa Izquierdo, Adela Escudero, Mireia Camós, Nerea Vega-García, Margarita Ortega, Gloria Hidalgo-Gómez, Carlos Palacio, Pablo Menéndez, Clara Bueno, Joan Montero, Paola A. Romecín, Santiago Zazo, Federico Alvarez, Juan Parras, Carmen Ortega-Sabater, Salvador Chulián, María Rosa, Davide Cirillo, Elena García, Jorge García, Albert Manzano-Muñoz, Alfredo Minguela, Jose L. Fuster
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with survival rates exceeding 85%. However, 15% of patients will relapse; consequently, their survival rates decrease to below 50%. Therefore, several research and innovation stu
Externí odkaz:
https://doaj.org/article/5124b9f3d98a4c79a13549557a869a45
Autor:
Carmen Mestre-Durán, Carla Martín-Cortázar, Blanca García-Solís, Alicia Pernas, Lidia Pertíñez, Víctor Galán, Luisa Sisinni, Laura Clares-Villa, Alfonso Navarro-Zapata, Karima Al-Akioui, Adela Escudero, Cristina Ferreras, Antonio Pérez-Martínez
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionNatural killer (NK) cells are lymphocytes from the innate immune system part of the first defense barrier against infected and transformed cells, representing 5%-15% of peripheral blood lymphocytes. The cytotoxic capacity of NK cells is c
Externí odkaz:
https://doaj.org/article/6e841a31af134385b8b7bf77ebe5d148
Autor:
Miriam Gutiérrez-Jimeno, Elena Panizo-Morgado, Marta Calvo-Imirizaldu, Víctor Galán-Gómez, Adela Escudero-López, Ana Patiño-García
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
We report the case of a 7-month-old female patient who developed acute megakaryoblastic leukemia 6 months after the appearance of skull bone lesions. Initial evaluation and diagnosis of this patient were challenging and only achieved thanks to genomi
Externí odkaz:
https://doaj.org/article/ef6e9d2cbf174227b2930aa10574ebc8
Autor:
Leila Cardoso, Víctor Galán‐Gómez, María Dolores Corral‐Sánchez, Antonio Pérez‐Martínez, Susana Riesco, María Isidoro‐García, Adela Escudero
Publikováno v:
Clinical Case Reports, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract The clinical and laboratory criteria for hemophagocytic lymphohistiocytosis should be taken into account during the juvenile myelomonocytic leukemia diagnosis, specifically in CBL syndrome, to reveal the presence of primary rather than secon
Externí odkaz:
https://doaj.org/article/94997c2fc864407facdd73e69d1f416a
Autor:
Víctor Galán-Gómez, Nerea Matamala, Beatriz Ruz-Caracuel, Paula Valle-Simón, Bárbara Ochoa-Fernández, Pilar Guerra-García, Alicia Pernas-Sánchez, Jordi Minguillón, Berta González, Isabel Martínez-Romera, Sonsoles San Román-Pacheco, Pablo Estival-Monteliú, Adrián Ibáñez-Navarro, Antonio Pérez-Martínez, Adela Escudero-López
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 6, p 881 (2022)
Relapsed and refractory (R/r) disease in paediatric acute leukaemia remains the first reason for treatment failure. Advances in molecular characterisation can ameliorate the identification of genetic biomarkers treatment strategies for this disease,
Externí odkaz:
https://doaj.org/article/d0436fe042e1442bb89c8541c325efd5
Autor:
Nerea Vega-García, Sara Perez-Jaume, Elena Esperanza-Cebollada, Clara Vicente-Garcés, Montserrat Torrebadell, Antonio Jiménez-Velasco, Margarita Ortega, Marta Llop, Lorea Abad, José Manuel Vagace, Alfredo Minguela, Marta Pratcorona, Joaquín Sánchez-Garcia, Clara B. García-Calderón, María Teresa Gómez-Casares, Estela Martín-Clavero, Adela Escudero, Marta Riñón Martinez-Gallo, Luz Muñoz, María Rosario Velasco, Marina García-Morin, Albert Català, Antonia Pascual, Pablo Velasco, José Mª. Fernández, Alvaro Lassaletta, José Luis Fuster, Isabel Badell, Águeda Molinos-Quintana, Antonio Molinés, Pilar Guerra-García, Antonio Pérez-Martínez, Miriam García-Abós, Reyes Robles Ortiz, Sandra Pisa, Rosa Adán, Cristina Díaz de Heredia, José Luis Dapena, Susana Rives, Manuel Ramírez-Orellana, Mireia Camós
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2021)
Robust and applicable risk-stratifying genetic factors at diagnosis in pediatric T-cell acute lymphoblastic leukemia (T-ALL) are still lacking, and most protocols rely on measurable residual disease (MRD) assessment. In our study, we aimed to analyze
Externí odkaz:
https://doaj.org/article/76d44086f8a049c3816cf6758487be24
Autor:
Talía Sainz, Valeria Pignataro, Donato Bonifazi, Simona Ravera, María José Mellado, Antonio Pérez-Martínez, Adela Escudero, Adriana Ceci, Cristina Calvo
Publikováno v:
Children, Vol 8, Iss 12, p 1191 (2021)
The evolving field of microbiome research offers an excellent opportunity for biomarker identification, understanding drug metabolization disparities, and improving personalized medicine. However, the complexities of host–microbe ecological interac
Externí odkaz:
https://doaj.org/article/5bebf60b495540bbaa82df3abe2b6316
Autor:
Lucía Fernández, Adrián Fernández, Isabel Mirones, Adela Escudero, Leila Cardoso, María Vela, Diego Lanzarot, Raquel de Paz, Alejandra Leivas, Miguel Gallardo, Antonio Marcos, Ana Belén Romero, Joaquín Martínez-López, Antonio Pérez-Martínez
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Natural killer group 2D (NKG2D) is a natural killer (NK) cell-activating receptor that recognizes different stress-induced ligands that are overexpressed in a variety of childhood and adult tumors. NKG2D chimeric antigen receptor (CAR) T cells have s
Externí odkaz:
https://doaj.org/article/ba4d2ea6112c49d98f6f8eef30f4f95d
Autor:
Maria Vela, David Bueno, Pablo González-Navarro, Ariadna Brito, Lucía Fernández, Adela Escudero, Jaime Valentín, Carmen Mestre-Durán, Marina Arranz-Álvarez, Rebeca Pérez de Diego, Marta Mendiola, José Juan Pozo-Kreilinger, Antonio Pérez-Martínez
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Sarcoma is one of the most severe forms of pediatric cancer and current therapies -chemotherapy and surgery- fail to eradicate the disease in half of patients. Preclinical studies combining new therapeutic approaches can be useful to design better th
Externí odkaz:
https://doaj.org/article/a6a5c167d5b64a9e8698729c083fc625