Výsledky vyhledávání - "Adel M. Al-Fatease"

Dual-drug loaded micelle for combinatorial therapy targeting HIF and mTOR signaling pathways for ovarian cancer treatment

Autor: Bhuvana Shyam Doddapaneni, Adel M. Al-Fatease, Adam W.G. Alani, Deepa A. Rao

Publikováno v: Journal of Controlled Release. 307:272-281

Mutations in the tumor protein (TP53) and the mammalian target of rapamycin (mTOR) pathway have been elucidated as driver mutations in ovarian carcinomas that transform into an invasive phenotype under hypoxic conditions. Chetomin (CHE) targets the h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccb562e7b8d88c5f24635f94ce8d816
https://doi.org/10.1016/j.jconrel.2019.06.036

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A targeted combinatorial therapy for Ewing's sarcoma

Autor: Mark Leid, Walter K. Vogel, Abraham S. Moses, Hassan A. Albarqi, Oleh Taratula, Youngrong Park, Ananiya A. Demessie, Adam W.G. Alani, Ellie Esfandiari Nazzaro, Olena Taratula, Adel M. Al-Fatease, Monika A. Davare, Fahad Y. Sabei

Publikováno v: Nanomedicine

Ewing's sarcoma (EwS) is the second most common bone cancer in children and adolescents. Current chemotherapy regimens are mainly ineffective in patients with relapsed disease and cause long-term effects in survivors. Therefore, we have developed a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3947f5ba81628cf909643d2ffea804b0
https://pubmed.ncbi.nlm.nih.gov/34303840

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