Maternal obesity in the ewe increases cardiac ventricular expression of glucocorticoid receptors, proinflammatory cytokines and fibrosis in adult male offspring.

Autor: Adel B Ghnenis, John F Odhiambo, Richard J McCormick, Peter W Nathanielsz, Stephen P Ford

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189977 (2017)

Obesity during human pregnancy predisposes offspring to obesity and cardiovascular disease in postnatal life. In a sheep model of maternal overnutrition/obesity we have previously reported myocardial inflammation and fibrosis, as well as cardiac dysf

Externí odkaz: https://doaj.org/article/972744facd204f3d9f4dce68eec20724

A Long-Term Pilot Study on Sex and Spinal Cord Injury Shows Sexual Dimorphism in Functional Recovery and Cardio-Metabolic Responses

Autor: Wupu Osimanjiang, Jared Bushman, Adel B. Ghnenis, Daniel T. Burns, Guanglong He

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

More than a quarter of a million individuals in the US live with spinal cord injury (SCI). SCI disrupts neural circuitry to vital organs in the body. Despite severe incidences of long-term peripheral complications from SCI, the cardio-metabolic conse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44d01684a79956e8c753a4cd0415085
http://link.springer.com/article/10.1038/s41598-020-59628-6

Author response for 'Long term neural regeneration following injury to the peroneal branch of the sciatic nerve in sheep'

Autor: null Kelly C.S. Roballo, null Daniel Burns, null Adel B. Ghnenis, null Wupu Osimanjiang, null Jared S. Bushman

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90498189c13a26ade72245af6847b6e7
https://doi.org/10.1111/ejn.14835/v3/response1

Rapid Communication: Reduced maternal nutrition during early- to mid-gestation elevates newborn lamb plasma cortisol concentrations and eliminates the neonatal leptin surge

Autor: Ashley M. Smith, Christopher L. Pankey, Adel B. Ghnenis, Peter W. Nathanielsz, Stephen P. Ford, John F. Odhiambo

Publikováno v: Journal of Animal Science. 96:2640-2645

Human epidemiological and animal studies show that maternal nutrient reduction (MNR) and maternal overnutrition/obesity (MO) alter fetal growth and development, predisposing offspring (F1) to endocrine and appetite dysregulation. Compared to F1 of co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bee4cddf3a589df3943c79d12368a2d
https://doi.org/10.1093/jas/sky215

A Review of Maternal Nutrition during Pregnancy and Impact on the Offspring through Development: Evidence from Animal Models of Over- and Undernutrition

Autor: Stephen P. Ford, Christopher L. Pankey, Adel B. Ghnenis, John F. Odhiambo

Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 17, Iss 6926, p 6926 (2020)

Similarities in offspring phenotype due to maternal under- or over-nutrition during gestation have been observed in studies conducted at University of Wyoming. In these studies, ewes were either nutrient-restricted (NR) from early to mid-gestation, o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696d0acd513288fc2e6f4a531aca962e
https://doi.org/10.3390/ijerph17186926