Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Adekunle M, Adesina"'
Autor:
Zi-Lu Huang, Zhi-Gang Liu, Qi Lin, Ya-Lan Tao, Xinzhuoyun Li, Patricia Baxter, Jack MF Su, Adekunle M. Adesina, Chris Man, Murali Chintagumpala, Wan Yee Teo, Yu-Chen Du, Yun-Fei Xia, Xiao-Nan Li
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101988- (2024)
Radiation is one of the standard therapies for pediatric high-grade glioma (pHGG), of which the prognosis remains poor. To gain an in-depth understanding of biological consequences beyond the classic DNA damage, we treated 9 patient-derived orthotopi
Externí odkaz:
https://doaj.org/article/42c4611929cf4552aa6cf7dffa17679b
Autor:
Daniel G. Calame, Jawid M. Fatih, Isabella Herman, Zeynep Coban‐Akdemir, Haowei Du, Tadahiro Mitani, Shalini N. Jhangiani, Dana Marafi, Richard A. Gibbs, Jennifer E. Posey, Vidya P. Mehta, Carrie A. Mohila, Farida Abid, Timothy E. Lotze, Davut Pehlivan, Adekunle M. Adesina, James R. Lupski
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 10, Pp 2052-2058 (2021)
Abstract Exome sequencing (ES) has revolutionized rare disease management, yet only ~25%–30% of patients receive a molecular diagnosis. A limiting factor is the quality of available phenotypic data. Here, we describe how deep clinicopathological ph
Externí odkaz:
https://doaj.org/article/cb34fe521e7d4c82ae7f6de309954374
Autor:
Cagla Y. Benkli, Andrea N. Marcogliese, Jennifer E. Agrusa, Adekunle M. Adesina, Howard L. Weiner, Kevin E. Fisher, Choladda V. Curry
Publikováno v:
Haematologica, Vol 106, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/0892fdd8062e4201a0623c4a9a7f10cd
Autor:
Bettina L Serrallach, Brandon H Tran, David F Bauer, Carrie A Mohila, Adekunle M Adesina, Susan L McGovern, Holly B Lindsay, Thierry AGM Huisman
Publikováno v:
The Neuroradiology Journal. 35:634-639
Primary spinal cord high-grade gliomas, including those histologically identified as glioblastoma (GBM), are a rare entity in the pediatric population but should be considered in the differential diagnosis of intramedullary lesions. Pediatric spinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d25c5156d13717f945b84b8fdef02d
https://doi.org/10.1177/19714009211067402
https://doi.org/10.1177/19714009211067402
Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Purpose: Pediatric glioblastoma multiforme (pGBM) is a highly aggressive tumor in need of novel therapies. Our objective was to demonstrate the therapeutic efficacy of MLN8237 (alisertib), an orally available selective inhibitor of Aurora A kinase (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add973a53fa03709cc14fba8c29ebe20
https://doi.org/10.1158/1078-0432.c.6526046
https://doi.org/10.1158/1078-0432.c.6526046
Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Supplementary Figure S1-S3 Figure S1. Anti-proliferative effects of MLN8237 on pGBM cell lines. Paired monolayer (Mono) and neurosphere (NS) of IC-4687GBM, IC-3752GBM and ICR0315GBM were seeded at 2,000 cells/well and exposed to MLN8237 (1 - 4,000 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf825c071ffe844120a4e784048d90e
https://doi.org/10.1158/1078-0432.22465520.v1
https://doi.org/10.1158/1078-0432.22465520.v1
Autor:
Sharon E. Plon, Raghu Chandramohan, Frank Y. Lin, Angshumoy Roy, Donna M. Muzny, Fatema Malbari, Kevin E. Fisher, Arnold C. Paulino, Stephen C. Mack, Jianhong Hu, Richard A. Gibbs, Jacquelyn Reuther, Marcia Kukreja, Daniel J. Curry, Ross Mangum, Adekunle M. Adesina, D. Williams Parsons, Murali Chintagumpala, Kelsey C. Bertrand
Publikováno v:
JCO Precis Oncol
Ependymomas comprise approximately 10 percent of childhood CNS malignancies and are associated with dismal outcomes if metastatic, incompletely resected, or recurrent.1 Standard therapy consists of maximal safe surgical resection followed by focal ir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a4db3bb5b2716c1b21062dad8eafb6
https://doi.org/10.1200/po.20.00375
https://doi.org/10.1200/po.20.00375
Autor:
Richard A. Gibbs, Vidya Mehta, Tadahiro Mitani, Shalini N. Jhangiani, James R. Lupski, Isabella Herman, Timothy Lotze, Haowei Du, Zeynep Coban-Akdemir, Davut Pehlivan, Daniel G. Calame, Dana Marafi, Farida Abid, Jawid M Fatih, Jennifer E. Posey, Adekunle M. Adesina, Carrie A. Mohila
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Vol 8, Iss 10, Pp 2052-2058 (2021)
Annals of Clinical and Translational Neurology, Vol 8, Iss 10, Pp 2052-2058 (2021)
Exome sequencing (ES) has revolutionized rare disease management, yet only ~25%–30% of patients receive a molecular diagnosis. A limiting factor is the quality of available phenotypic data. Here, we describe how deep clinicopathological phenotyping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961ca042c9e9ed7146146386d20f58d4
http://europepmc.org/articles/PMC8528454
http://europepmc.org/articles/PMC8528454
Autor:
Andrea N. Marcogliese, Choladda V. Curry, Howard L. Weiner, Cagla Y Benkli, Kevin E. Fisher, Adekunle M. Adesina, Jennifer E. Agrusa
Publikováno v:
Haematologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc1db8066ac654b672fdab5bdd14e5f
http://europepmc.org/articles/PMC8409016
http://europepmc.org/articles/PMC8409016
Autor:
Fady Hannah-Shmouni, Giampaolo Trivellin, Pablo Beckers, Lefkothea P. Karaviti, Maya Lodish, Christina Tatsi, Adekunle M. Adesina, Fotini Adamidou, Gesthimani Mintziori, Jami L. Josefson, Martha Quezado, Constantine A. Stratakis
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 8; Pages: 2168
Overgrowth due to growth hormone (GH) excess affects approximately 10% of patients with neurofibromatosis type 1 (NF1) and optic pathway glioma (OPG). Our aim is to describe the clinical, biochemical, pathological, and genetic features of GH excess i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e11852c6c4f683dc62d964d55b72954