Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Adegbenro P. Adegunloye"'
Autor:
Habibu Tijjani, Adegbenro P. Adegunloye, Auwalu Uba, Joseph O. Adebayo, Gideon A. Gyebi, Ibrahim M. Ibrahim
Publikováno v:
Clinical Phytoscience, Vol 8, Iss 1, Pp 1-15 (2022)
Highlights • Flavonoids displayed varying affinities for PLpro and 3CLpro of SARS-CoV-2 • They interacted via hydrogen and non-hydrogen bonds; nine and twenty-seven flavonoids had better binding affinities for PLpro and 3CLpro respectively than l
Externí odkaz:
https://doaj.org/article/0b24ee5c3ccc4b068b6477398ec5bb6f
Autor:
Gideon A. Gyebi, Oludare M. Ogunyemi, Ibrahim M. Ibrahim, Olalekan B. Ogunro, Adegbenro P. Adegunloye, Saheed O. Afolabi
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background Targeting viral cell entry proteins is an emerging therapeutic strategy for inhibiting the first stage of SARS-CoV-2 infection. In this study, 106 bioactive terpenoids from African medicinal plants were screened through molecular
Externí odkaz:
https://doaj.org/article/8a6a82e019ea4bab86f642d535b1d552
Publikováno v:
Scientific African, Vol 8, Iss , Pp e00429- (2020)
Daucus carota seed is medicinally useful in the management of disease such as diabetes mellitus, which is associated with oxidative stress. This study investigated the phytochemical constituents, in vitro and in vivo antioxidant activities of aqueous
Externí odkaz:
https://doaj.org/article/92b319e9374742e3b7b359a2daa31bb8
Autor:
Adegbenro P. Adegunloye, Gideon A. Gyebi, Oludare M. Ogunyemi, Olalekan B. Ogunro, Ibrahim M. Ibrahim, Saheed O. Afolabi
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 19, Iss 1, Pp 1-22 (2021)
Journal of Genetic Engineering & Biotechnology
Journal of Genetic Engineering & Biotechnology
Background Targeting viral cell entry proteins is an emerging therapeutic strategy for inhibiting the first stage of SARS-CoV-2 infection. In this study, 106 bioactive terpenoids from African medicinal plants were screened through molecular docking a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37254bb7211a7c02fbb79561be89d708
https://doaj.org/article/8a6a82e019ea4bab86f642d535b1d552
https://doaj.org/article/8a6a82e019ea4bab86f642d535b1d552
Autor:
Olalekan B. Ogunro, Adegbenro P. Adegunloye, Oludare M. Ogunyemi, Saheed O. Afolabi, Gideon A. Gyebi
Publikováno v:
Journal of Biomolecular Structure and Dynamics
Journal of Biomolecular Structure & Dynamics
Journal of Biomolecular Structure & Dynamics
The novel coronavirus disease 2019 (COVID-19) caused by SARS-COV-2 has raised myriad of global concerns. There is currently no FDA approved antiviral strategy to alleviate the disease burden. The conserved 3-chymotrypsin-like protease (3CLpro), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9507ae2bad92ca42fe140270d4492d7c
https://doi.org/10.1080/07391102.2020.1764868
https://doi.org/10.1080/07391102.2020.1764868
Autor:
Gideon A. Gyebi, Oludare M. Ogunyemi, Adedotun A. Adefolalu, Juan F. López-Pastor, Antonio J. Banegas-Luna, Alejandro Rodríguez-Martínez, Horacio Pérez-Sánchez, Adegbenro P. Adegunloye, Olalekan B. Ogunro, Saheed O. Afolabi, Alaa Baazeem, Saqer S. Alotaibi, Gaber El-Saber Batiha
The inhibition of capping enzymes such as guanine-N7-methyltransferase (GMT) is an attractive target for regulating viral replication, transcription, virulence, and pathogenesis. Thus, compounds that target the Severe Acute Respiratory Syndrome Coron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f41f995ae7c020114c0488ccf4eddb
Autor:
Gideon A, Gyebi, Oludare M, Ogunyemi, Adedotun A, Adefolalu, Alejandro, Rodríguez-Martínez, Juan F, López-Pastor, Antonio J, Banegas-Luna, Horacio, Pérez-Sánchez, Adegbenro P, Adegunloye, Olalekan B, Ogunro, Saheed O, Afolabi
Publikováno v:
Journal of molecular structure. 1262
Despite the ongoing vaccination against the life-threatening COVID-19, there is need for viable therapeutic interventions. The S-adenosyl-l-Methionine (SAM) dependent 2-O'-ribose methyltransferase (2'-O-MTase) of the severe acute respiratory syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6eb18a7d69d3d4df8830a7a8ae587763
https://pubmed.ncbi.nlm.nih.gov/35431328
https://pubmed.ncbi.nlm.nih.gov/35431328
Autor:
Oludare M Ogunyemi, Gyebi, Gideon A, Elfiky, Abdo A, Saheed O Afolabi, Olalekan B Ogunro, Adegbenro P Adegunloye, Ibrahim, Ibrahim M
Supplemental material, sj-pdf-1-avc-10.1177_2040206620984076 for Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective by Oludare M Ogunyemi, Gideon A Gyebi,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6404ef51905a626054690c8160f6bec6
Autor:
Gideon A. Gyebi, Oludare M. Ogunyemi, Adedotun A. Adefolalu, Alejandro Rodríguez-Martínez, Juan F. López-Pastor, Antonio J. Banegas-Luna, Horacio Pérez-Sánchez, Adegbenro P. Adegunloye, Olalekan B. Ogunro, Saheed O. Afolabi
Publikováno v:
Journal of Molecular Structure. 1262:133019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e31ba444fa23ff0b81d0c4a905ce7424
https://doi.org/10.1016/j.molstruc.2022.133019
https://doi.org/10.1016/j.molstruc.2022.133019
Autor:
Modupe M. Fabusiwa, Oludare M. Ogunyemi, Adegbenro P. Adegunloye, Charles O. Olaiya, Gideon A. Gyebi, Abdo A. Elfiky, Joseph O. Adebayo, Ibrahim M. Ibrahim, Joshua O. Ocheje
Publikováno v:
Computers in Biology and Medicine
Antiviral culinary plants are potential bioresources for preventive nutraceuticals and/or antiviral drugs in COVID-19. Structure-based virtual screening was undertaken to screen 173 compounds previously reported from Vernonia amygdalina and Occinum g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ef74e29db3bcf003529efb8657ca28
https://doi.org/10.21203/rs.3.rs-301445/v1
https://doi.org/10.21203/rs.3.rs-301445/v1