In vitro antimalarial activity of methylene blue against field isolates of Plasmodium falciparum from children in Southwest Nigeria

Autor: Ademowo, OG, Nneji, CM, Adedapo, ADA

BACKGROUND & OBJECTIVES: Methylene blue (MB), a thiazine dye is used in the treatment of various methemoglobinaemias. However, sporadic reports have shown some antimalarial therapeutic effect when administered to patients with clinical manifestations

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Clofibrate, a Peroxisome Proliferator-Activated Receptor-Alpha (PPARα) Agonist, and Its Molecular Mechanisms of Action against Sodium Fluoride-Induced Toxicity.

Autor: Oyagbemi AA; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria. ademola.oyagbemi778@gmail.com., Adejumobi OA; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Jarikre TA; Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Ajani OS; Department of Theriogenology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Asenuga ER; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Benin, Benin, Nigeria., Gbadamosi IT; Department of Botany, Faculty of Science, University of Ibadan, Ibadan, Nigeria., Adedapo ADA; Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria., Aro AO; Department of Agriculture and Animal Health, College of Agriculture and Environmental Sciences, University of South Africa, Florida, South Africa., Ogunpolu BS; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Hassan FO; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Falayi OO; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Ogunmiluyi IO; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Omobowale TO; Department of Veterinary Medicine, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Arojojoye OA; Department of Biochemistry, Faculty of Sciences, Lead City University, Ibadan, Nigeria., Ola-Davies OE; Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Saba AB; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Adedapo AA; Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Emikpe BO; Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Oyeyemi MO; Department of Theriogenology, Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria., Nkadimeng SM; Phytomedicine Programme, Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, Old Soutpan Road, Onderstepoort, Pretoria, 0110, South Africa., McGaw LJ; Phytomedicine Programme, Department of Paraclinical Science, Faculty of Veterinary Science, University of Pretoria, Old Soutpan Road, Onderstepoort, Pretoria, 0110, South Africa., Kayoka-Kabongo PN; Department of Agriculture and Animal Health, College of Agriculture and Environmental Sciences, University of South Africa, Florida, South Africa., Oguntibeju OO; Phytomedicine and Phytochemistry Group, Oxidative Stress Research Centre, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, Cape Town, 7535, South Africa., Yakubu MA; Department of Environmental & Interdisciplinary Sciences, College of Science, Engineering & Technology, Vascular Biology Unit, Center for Cardiovascular Diseases, Texas Southern University, Houston, TX, USA.

Publikováno v: Biological trace element research [Biol Trace Elem Res] 2022 Mar; Vol. 200 (3), pp. 1220-1236. Date of Electronic Publication: 2021 Apr 24.

Chrysophyllum albidum fruit ethanol extract ameliorates hyperglycaemia and elevated blood pressure in streptozotocin-induced diabetic rats through modulation of oxidative stress, NF-κB and PPAR-γ.

Autor: Ajayi AM; Department of Pharmacology & Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Electronic address: yomex@yahoo.com., Adedapo ADA; Department of Pharmacology & Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Electronic address: debyee1965@yahoo.co.uk., Badaki VB; Department of Pharmacology & Therapeutics, Faculty of Basic Medical Sciences, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. Electronic address: badakibukola19@gmail.com., Oyagbemi AA; Department of Veterinary Physiology and Biochemistry, University of Ibadan, Ibadan, Oyo State, Nigeria. Electronic address: Ademola.oyagbemi778@gmail.com., Adedapo AA; Department of Veterinary Pharmacology and Toxicology, University of Ibadan, Ibadan, Oyo State, Nigeria. Electronic address: adedapo2a@gmail.com.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Sep; Vol. 141, pp. 111879. Date of Electronic Publication: 2021 Jul 02.

Cohort study on adverse drug reactions in adults admitted to the medical wards of a tertiary hospital in Nigeria: Prevalence, incidence, risk factors and fatality.

Autor: Adedapo ADA; Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Oyo State, Nigeria.; Department of Clinical Pharmacology, University College Hospital, Ibadan, Oyo State, Nigeria., Adedeji WA; Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Oyo State, Nigeria.; Department of Clinical Pharmacology, University College Hospital, Ibadan, Oyo State, Nigeria., Adedapo IA; Department of Family Medicine, University College Hospital, Ibadan, Ibadan, Nigeria., Adedapo KS; Department of Chemical Pathology, College of Medicine, University College Hospital, Ibadan, Ibadan, Nigeria.

Publikováno v: British journal of clinical pharmacology [Br J Clin Pharmacol] 2021 Apr; Vol. 87 (4), pp. 1878-1889. Date of Electronic Publication: 2020 Oct 27.